Pericardial closure with extracellular matrix scaffold following cardiac surgery associated with a reduction of postoperative complications and 30-day hospital readmissions

• Published in: Journal of cardiothoracic surgery Vol. 14; no. 1; pp. 61 - 10
• Main Authors: Rego, Alfredo, Cheung, Patricia C, Harris, William J, Brady, Kevin M, Newman, Jeffrey, Still, Robert
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 15.03.2019; BioMed Central; BMC
• Subjects: Aged; Ambulatory care facilities; Animals; Atrial fibrillation; Atrial Fibrillation - etiology; Bleeding; Cardiac arrhythmia; Cardiac Surgical Procedures - adverse effects; Cardiac Surgical Procedures - methods; Cardiac Valve Annuloplasty - adverse effects; Care and treatment; Catheters; Clinical outcomes; Comorbidity; Comparative analysis; Complications; Complications and side effects; Coronary artery; Coronary artery bypass; Coronary Artery Bypass - adverse effects; Coronary artery bypass grafting; Coronary vessels; Demographics; Demography; Extracellular matrix; Extracellular Matrix - transplantation; Female; Fibrillation; Heart; Heart surgery; Heart Valve Prosthesis Implantation - adverse effects; Hospital patients; Hospitals; Humans; Internet; Intestine; Male; Medical research; Middle Aged; Mortality; Patient Readmission; Patients; Pericardial closure; Pericardial effusion; Pericardial Effusion - etiology; Pericardium - surgery; Pleural effusion; Pleural Effusion - etiology; Postoperative complications; Postoperative Complications - etiology; Postoperative Hemorrhage - etiology; Postoperative period; Prospective Studies; Reduction; Risk analysis; Risk factors; Studies; Surgery; Swine; Systematic review; Tissue Scaffolds; Transplantation, Heterologous; Valve repair; Veins & arteries; Wound Closure Techniques; United States > US; Pericardial closure; Post-op atrial fibrillation; Coronary artery bypass grafting; Pleural effusion; Extracellular matrix; Valve repair; Pericardial effusion

A prospective, multi-center study (RECON) was conducted to evaluate the clinical outcomes of pericardial closure using a decellularized extracellular matrix (ECM) graft derived from porcine small intestinal submucosa. Patients indicated for open cardiac surgery with pericardial closure using ECM wer...