The amyloid hypothesis of Alzheimer's disease at 25 years - Selkoe, Dennis J; Hardy, John (EMBO molecular medicine, 2016)
Keywords: Alzheimer; Alzheimer Disease - pathology; Alzheimer Disease - physiopathology; Alzheimer's disease; Amyloid beta-Peptides - metabolism; Amyloid beta-Protein Precursor - metabolism; Amyloid precursor protein; Animals; Apolipoprotein E4; Brain - pathology; Brain damage; cell biology; Cerebrospinal fluid; Clinical trials; Cognitive ability; Dementia; Down's syndrome; Dystrophy; EMBO27; Epitopes; Gene expression; genetics; Gliosis; Humans; Hypotheses; Immunoglobulins; Laboratories; Metabolism; Mice, Transgenic; Mutation; Neurodegenerative diseases; Neurofibrillary tangles; Neurotoxicity; Phosphorylation; Positron emission tomography; Potentiation; Presenilin; Presenilins - metabolism; Proteins; Rats; Review; Secretase; Synapses; Synaptic depression; Tau protein; Therapeutic applications; Transgenic mice; treatment; Aβ; treatment; genetics; cell biology; Alzheimer