Metabolomics of Cerebrospinal Fluid from Healthy Subjects Reveal Metabolites Associated with Ageing

• Published in: Metabolites Vol. 11; no. 2; p. 126
• Main Authors: Carlsson, Henrik, Rollborn, Niclas, Herman, Stephanie, Freyhult, Eva, Svenningsson, Anders, Burman, Joachim, Kultima, Kim
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 23.02.2021; MDPI
• Subjects: Age; ageing; Aging; Amino acids; Biomarkers; Brain; Central nervous system; Cerebrospinal fluid; Disease; Gender; high-resolution mass spectrometry; Isoleucine; Liquid chromatography; Mass spectroscopy; Metabolism; Metabolites; Metabolomics; Methionine; Plasma; Urine; high-resolution mass spectrometry; ageing; metabolomics; cerebrospinal fluid

To increase our understanding of age-related diseases affecting the central nervous system (CNS) it is important to understand the molecular processes of biological ageing. Metabolomics of cerebrospinal fluid (CSF) is a promising methodology to increase our understanding of naturally occurring proce...