Infrared inhibition impacts on locally initiated and propagating action potentials and the downstream synaptic transmission

• Published in: Neurophotonics (Print) Vol. 7; no. 4; p. 045003
• Main Authors: Zhu, Xuedong, Lin, Jen-Wei, Sander, Michelle Y
• Format: Journal Article
• Language: English
• Published: United States Society of Photo-Optical Instrumentation Engineers 01.10.2020; S P I E - International Society for
• Subjects: Electrodes; Light; Localization; Motor neurons; Muscle contraction; Nerves; Nervous system; Neural networks; Neuromuscular junctions; Physiology; Research Papers; Synaptic transmission; Temperature; Therapeutic applications; United States > US; California; infrared nerve inhibition; action potential initiation; synaptic transmission; photothermal effect; action potential propagation; neural modulation

Significance: Systematic studies of the physiological outputs induced by infrared (IR)-mediated inhibition of motor nerves can provide guidance for therapeutic applications and offer critical insights into IR light modulation of complex neural networks. Aim: We explore the IR-mediated inhibition of...