Deblur Rapidly Resolves Single-Nucleotide Community Sequence Patterns

• Published in: mSystems Vol. 2; no. 2
• Main Authors: Amir, Amnon, McDonald, Daniel, Navas-Molina, Jose A., Kopylova, Evguenia, Morton, James T., Zech Xu, Zhenjiang, Kightley, Eric P., Thompson, Luke R., Hyde, Embriette R., Gonzalez, Antonio, Knight, Rob
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.03.2017
• Subjects: DNA sequencing; Editor's Pick; microbiome; Next-generation sequencing; Observation; microbiome; DNA sequencing

Deblur provides a rapid and sensitive means to assess ecological patterns driven by differentiation of closely related taxa. This algorithm provides a solution to the problem of identifying real ecological differences between taxa whose amplicons differ by a single base pair, is applicable in an aut...