Oxysterols and apolipoproteins in multiple sclerosis: a 5 year follow-up study[S]

• Published in: Journal of lipid research Vol. 60; no. 7; pp. 1190 - 1198
• Main Authors: Fellows Maxwell, Kelly, Bhattacharya, Sonia, Bodziak, Mary Lou, Jakimovski, Dejan, Hagemeier, Jesper, Browne, Richard W., Weinstock-Guttman, Bianca, Zivadinov, Robert, Ramanathan, Murali
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2019; The American Society for Biochemistry and Molecular Biology; Elsevier
• Subjects: Adolescent; Adult; Aged; Apolipoproteins - blood; cholesterol; disease progression; Female; Follow-Up Studies; Humans; Hydroxycholesterols - blood; Ketocholesterols - blood; Longitudinal Studies; Male; Mass Spectrometry; metabolism; Middle Aged; Multiple Sclerosis - blood; Multiple Sclerosis - pathology; Oxysterols - blood; Prospective Studies; Young Adult; cholesterol; metabolism; disease progression

The purpose of this work was to investigate whether changes in oxysterol and apolipoprotein levels over 5 years are associated with disease course and disability progression in multiple sclerosis (MS). This study included 139 subjects [39 healthy controls (HCs), 61 relapsing-remitting MS (RR-MS) pat...