A Review of Liposomes as a Drug Delivery System: Current Status of Approved Products, Regulatory Environments, and Future Perspectives

• Published in: Molecules (Basel, Switzerland) Vol. 27; no. 4; p. 1372
• Main Authors: Liu, Peng, Chen, Guiliang, Zhang, Jingchen
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 17.02.2022; MDPI
• Subjects: Cancer therapies; Consumer Product Safety; Drug and Narcotic Control; Drug Approval; Drug Carriers - chemistry; drug delivery; Drug Delivery Systems; drug loading; Europe; Fatty acids; FDA approval; Growth factors; Humans; Ligands; lipid excipient; Lipids; liposomes; Liposomes - chemistry; marketed products; Molecular Structure; Molecular weight; Particle size; Phase transitions; Physiology; Review; United States; United States Food and Drug Administration; United States; Europe; drug loading; drug delivery; liposomes; lipid excipient; marketed products

Liposomes have been considered promising and versatile drug vesicles. Compared with traditional drug delivery systems, liposomes exhibit better properties, including site-targeting, sustained or controlled release, protection of drugs from degradation and clearance, superior therapeutic effects, and...