Antimicrobial activity of the green tea polyphenol (−)-epigallocatechin-3-gallate (EGCG) against clinical isolates of Stenotrophomonas maltophilia

• Published in: International journal of antimicrobial agents Vol. 36; no. 2; pp. 129 - 131
• Main Authors: Gordon, Nicola C, Wareham, David W
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.08.2010; Elsevier
• Subjects: Agar; Anti-Bacterial Agents - pharmacology; Antibiotics. Antiinfectious agents. Antiparasitic agents; Biological and medical sciences; Camellia sinensis; Catechin - analogs & derivatives; Catechin - pharmacology; EGCG; Gram-Negative Bacterial Infections - microbiology; Humans; Infectious Disease; Medical sciences; Microbial Sensitivity Tests; Pharmacology. Drug treatments; Stenotrophomonas maltophilia; Stenotrophomonas maltophilia - drug effects; Stenotrophomonas maltophilia - isolation & purification; Stenotrophomonas maltophilia; EGCG; Pseudomonadales; Human; Biological activity; Antimicrobial agent; Polyphenol; Epigallocatechin gallate; Phenols; Bacteria; Pseudomonadaceae; Clinical isolate; Green tea

Abstract Stenotrophomonas maltophilia is increasingly recognised as an important nosocomial pathogen. Treatment options are limited due to intrinsic resistance to many antibiotics as well as concerns over toxicity of the mainstay of treatment, co-trimoxazole. Epigallocatechin-3-gallate (EGCG), the m...