Tetramethylpyrazine reverses high-glucose induced hypoxic effects by negatively regulating HIF-1α induced BNIP3 expression to ameliorate H9c2 cardiomyoblast apoptosis - Liu, Shih-Ping; Shibu, Marthandam Asokan; Tsai, Fuu-Jen; Hsu, Yuan-Man; Tsai, Chang-Hai; Chung, Jing-Gung; Yang, Jai-Sing; Tang, Chih-Hsin; Wang, Shulin; Li, Qiaowen; Huang, Chih-Yang (Nutrition & metabolism, 2020)
Keywords: Apoptosis; BNIP3 protein; Cardiomyocytes; Cardiovascular disease; Caspase; Cell viability; Cytotoxicity; Diabetes; Diabetes mellitus; Flavors; Food flavoring; Gene expression; Glucose; HIF-1; Hyperglycemia; Hypoxia; hypoxia-inducible factor 1; Membranes; Metabolism; nutrition; patients; protein synthesis; Proteins; pyrazines; United States--US; Caspase; HIF-1; Hypoxia; Diabetes mellitus; Food flavoring