Adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) Hull Extract and Active Compounds Inhibit Proliferation of Primary Human Leiomyoma Cells and Protect against Sexual Hormone-Induced Mice Smooth Muscle Hyperproliferation

• Published in: Molecules (Basel, Switzerland) Vol. 24; no. 8; p. 1556
• Main Authors: Lin, Po-Han, Shih, Chun-Kuang, Yen, Yu-Ting, Chiang, Wenchang, Hsia, Shih-Min
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 19.04.2019; MDPI
• Subjects: adlay hull; Cell growth; Colorectal cancer; Drug dosages; Efficiency; Fibroids; Menstruation; Seeds; Smooth muscle; stigmasterol; Traditional Chinese medicine; Uterine cancer; uterine leiomyomas; Uterus; Womens health; uterine leiomyomas; adlay hull; stigmasterol; fibroids

Uterine leiomyomas, also known as fibroids, are benign neoplasms of the uterus and have a high incidence rate in women of reproductive age. Hysterectomy or myomectomy is the initial treatment, but fibroids will recur if the patient is still exposed to similar risk factors. Therefore, developing new...