Citrus Extract High in Flavonoids Beneficially Alters Intestinal Metabolic Responses in Subjects with Features of Metabolic Syndrome

• Published in: Foods Vol. 12; no. 18; p. 3413
• Main Authors: Maurer Sost, Mônica, Stevens, Yala, Salden, Bouke, Troost, Freddy, Masclee, Ad, Venema, Koen
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.09.2023; MDPI
• Subjects: Acetates; Acetic acid; butyrates; Citrus; citrus extract; Citrus fruits; Colon; Dialysate; Dietary supplements; Esters; Fatty acids; Feces; Females; Fermentation; Flavonoids; Food science; Fruits; Glucose; Health care; Human subjects; humans; in vitro model; inflammation; Intestine; Isoflavones; Lifestyles; Males; Medical research; Medicine, Experimental; Metabolic disorders; Metabolic response; Metabolic syndrome; Metabolites; Microbiota; Peptides; Physiology; Placebos; short chain fatty acids; short-chain fatty acids (SCFAs); TIM-2; Type 2 diabetes; Netherlands

The objective of this study was to investigate the effects of a citrus extract rich in citrus flavonoids on intestinal metabolic responses in subjects with features of metabolic syndrome, in an in vitro colon fermentation system (TIM-2) and fecal samples obtained from human subjects in an in vivo tr...