Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects

• Published in: Molecules (Basel, Switzerland) Vol. 27; no. 1; p. 233
• Main Authors: Rahman, Md. Mominur, Rahaman, Md. Saidur, Islam, Md. Rezaul, Rahman, Firoza, Mithi, Faria Mannan, Alqahtani, Taha, Almikhlafi, Mohannad A., Alghamdi, Samia Qasem, Alruwaili, Abdullah S, Hossain, Md. Sohel, Ahmed, Muniruddin, Das, Rajib, Emran, Talha Bin, Uddin, Md. Sahab
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 30.12.2021; MDPI
• Subjects: Acids; Alzheimer's disease; Animals; Anti-Infective Agents - chemistry; Anti-Infective Agents - pharmacology; Anti-Infective Agents - therapeutic use; Anti-Inflammatory Agents - chemistry; Anti-Inflammatory Agents - pharmacology; Anti-Inflammatory Agents - therapeutic use; Antihypertensive Agents - chemistry; Antihypertensive Agents - pharmacology; Antihypertensive Agents - therapeutic use; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; antioxidant; Antioxidants; Antioxidants - chemistry; Antioxidants - pharmacology; Antioxidants - therapeutic use; Antiviral drugs; Apoptosis; Bioavailability; Biological Availability; Biological Products - chemistry; Biological Products - pharmacology; Biological Products - therapeutic use; Cardiovascular disease; Cereals; Chronic illnesses; Coffee; Dementia; Diabetes; diabetic mellitus; Disease Management; Drug Evaluation, Preclinical; Fruits; Health Impact Assessment; Homeostasis; Humans; Hypertension; Hypoglycemic Agents - chemistry; Hypoglycemic Agents - pharmacology; Hypoglycemic Agents - therapeutic use; inflammation; Insulin; Metabolism; Metabolites; Microorganisms; Mitochondria; Nitrogen; Oxidative stress; phenolic compounds; Phenols - chemistry; Phenols - pharmacology; Phenols - therapeutic use; Physiology; Plant Extracts - chemistry; Plant Extracts - pharmacology; Plant Extracts - therapeutic use; Polyphenols; Review; Structure-Activity Relationship; Tea; Vegetables; phenolic compounds; cardiovascular disease; antioxidant; inflammation; diabetic mellitus; hypertension

Inflammation is a natural protective mechanism that occurs when the body’s tissue homeostatic mechanisms are disrupted by biotic, physical, or chemical agents. The immune response generates pro-inflammatory mediators, but excessive output, such as chronic inflammation, contributes to many persistent...