Mitochondrial DNA–Deletion Mutations Accumulate Intracellularly to Detrimental Levels in Aged Human Skeletal Muscle Fibers - Bua, Entela; Johnson, Jody; Herbst, Allen; Delong, Bridget; McKenzie, Debbie; Salamat, Shahriar; Aiken, Judd M. (American journal of human genetics, 2006)
Keywords: Aged; Aged, 80 and over; Aging; Aging - genetics; Biological and medical sciences; DNA, Mitochondrial - analysis; DNA, Mitochondrial - genetics; Electron Transport - genetics; Electron Transport Chain Complex Proteins - genetics; Electron Transport Complex IV - genetics; Female; General aspects. Genetic counseling; Genotype & phenotype; Humans; Male; Medical genetics; Medical sciences; Middle Aged; Mitochondria, Muscle - enzymology; Mitochondria, Muscle - genetics; Mitochondrial DNA; Muscle Fibers, Skeletal - chemistry; Muscle Fibers, Skeletal - cytology; Muscle Fibers, Skeletal - enzymology; Muscle, Skeletal - chemistry; Muscle, Skeletal - cytology; Muscle, Skeletal - enzymology; Musculoskeletal system; Mutation; Sequence Deletion; Succinate Dehydrogenase - genetics; Human; Deletion; Genetics; Mitochondrial DNA; Mutation; Striated muscle