Unique Roles of Gold Nanoparticles in Drug Delivery, Targeting and Imaging Applications

Nanotechnology has become more and more potentially used in diagnosis or treatment of diseases. Advances in nanotechnology have led to new and improved nanomaterials in biomedical applications. Common nanomaterials applicable in biomedical applications include liposomes, polymeric micelles, graphene...

Full description

Saved in:
Bibliographic Details
Published inMolecules (Basel, Switzerland) Vol. 22; no. 9; p. 1445
Main Authors Kong, Fen-Ying, Zhang, Jin-Wei, Li, Rong-Fang, Wang, Zhong-Xia, Wang, Wen-Juan, Wang, Wei
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 31.08.2017
MDPI
Subjects
Online AccessGet full text

Cover

Loading…
Abstract Nanotechnology has become more and more potentially used in diagnosis or treatment of diseases. Advances in nanotechnology have led to new and improved nanomaterials in biomedical applications. Common nanomaterials applicable in biomedical applications include liposomes, polymeric micelles, graphene, carbon nanotubes, quantum dots, ferroferric oxide nanoparticles, gold nanoparticles (Au NPs), and so on. Among them, Au NPs have been considered as the most interesting nanomaterial because of its unique optical, electronic, sensing and biochemical properties. Au NPs have been potentially applied for medical imaging, drug delivery, and tumor therapy in the early detection, diagnosis, and treatment of diseases. This review focuses on some recent advances in the use of Au NPs as drug carriers for the intracellular delivery of therapeutics and as molecular nanoprobes for the detection and monitoring of target molecules.
AbstractList Nanotechnology has become more and more potentially used in diagnosis or treatment of diseases. Advances in nanotechnology have led to new and improved nanomaterials in biomedical applications. Common nanomaterials applicable in biomedical applications include liposomes, polymeric micelles, graphene, carbon nanotubes, quantum dots, ferroferric oxide nanoparticles, gold nanoparticles (Au NPs), and so on. Among them, Au NPs have been considered as the most interesting nanomaterial because of its unique optical, electronic, sensing and biochemical properties. Au NPs have been potentially applied for medical imaging, drug delivery, and tumor therapy in the early detection, diagnosis, and treatment of diseases. This review focuses on some recent advances in the use of Au NPs as drug carriers for the intracellular delivery of therapeutics and as molecular nanoprobes for the detection and monitoring of target molecules.
Nanotechnology has become more and more potentially used in diagnosis or treatment of diseases. Advances in nanotechnology have led to new and improved nanomaterials in biomedical applications. Common nanomaterials applicable in biomedical applications include liposomes, polymeric micelles, graphene, carbon nanotubes, quantum dots, ferroferric oxide nanoparticles, gold nanoparticles (Au NPs), and so on. Among them, Au NPs have been considered as the most interesting nanomaterial because of its unique optical, electronic, sensing and biochemical properties. Au NPs have been potentially applied for medical imaging, drug delivery, and tumor therapy in the early detection, diagnosis, and treatment of diseases. This review focuses on some recent advances in the use of Au NPs as drug carriers for the intracellular delivery of therapeutics and as molecular nanoprobes for the detection and monitoring of target molecules.Nanotechnology has become more and more potentially used in diagnosis or treatment of diseases. Advances in nanotechnology have led to new and improved nanomaterials in biomedical applications. Common nanomaterials applicable in biomedical applications include liposomes, polymeric micelles, graphene, carbon nanotubes, quantum dots, ferroferric oxide nanoparticles, gold nanoparticles (Au NPs), and so on. Among them, Au NPs have been considered as the most interesting nanomaterial because of its unique optical, electronic, sensing and biochemical properties. Au NPs have been potentially applied for medical imaging, drug delivery, and tumor therapy in the early detection, diagnosis, and treatment of diseases. This review focuses on some recent advances in the use of Au NPs as drug carriers for the intracellular delivery of therapeutics and as molecular nanoprobes for the detection and monitoring of target molecules.
Author Kong, Fen-Ying
Li, Rong-Fang
Wang, Wei
Wang, Wen-Juan
Zhang, Jin-Wei
Wang, Zhong-Xia
AuthorAffiliation School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, China; kongfy@ycit.edu.cn (F.-Y.K.); zhangjinwei18@163.com (J.-W.Z.); Lirongfang2324@163.com (R.-F.L.); wangzx198411@163.com (Z.-X.W.); wwj@ycit.edu.cn (W.-J.W.)
AuthorAffiliation_xml – name: School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, China; kongfy@ycit.edu.cn (F.-Y.K.); zhangjinwei18@163.com (J.-W.Z.); Lirongfang2324@163.com (R.-F.L.); wangzx198411@163.com (Z.-X.W.); wwj@ycit.edu.cn (W.-J.W.)
Author_xml – sequence: 1
  givenname: Fen-Ying
  surname: Kong
  fullname: Kong, Fen-Ying
– sequence: 2
  givenname: Jin-Wei
  surname: Zhang
  fullname: Zhang, Jin-Wei
– sequence: 3
  givenname: Rong-Fang
  surname: Li
  fullname: Li, Rong-Fang
– sequence: 4
  givenname: Zhong-Xia
  surname: Wang
  fullname: Wang, Zhong-Xia
– sequence: 5
  givenname: Wen-Juan
  surname: Wang
  fullname: Wang, Wen-Juan
– sequence: 6
  givenname: Wei
  surname: Wang
  fullname: Wang, Wei
BackLink https://www.ncbi.nlm.nih.gov/pubmed/28858253$$D View this record in MEDLINE/PubMed
BookMark eNp1kk1r3DAQhkVJab76A3ophl566Db6tK1LISRtuhBSKAk5Clkeu1pkyZXsQP595eymJCk9aRi976PRzByiPR88IPSO4M-MSXwyBAdmdpAoxZJwLl6hA8IpXjHM5d6TeB8dprTBmBJOxBu0T-ta1FSwA3R74-3vGYqfGZWK0BUXwbXFlfZh1HGyZslaX5zHuS_Owdk7iPefimsde5is7wvt22I96H6JT8fRWaMnG3w6Rq877RK83Z1H6Obb1-uz76vLHxfrs9PLlRFCTivGGVQYylISWoEUkpuS11Ji3lJKRCc6SU1N2s4wIUUrCEiOqQbamA6EAXaE1ltuG_RGjdEOOt6roK16SITYq90_VEaVZQnQ5kd43fDGtBQLzLRosCYEZ9aXLWucmwFaA36K2j2DPr_x9pfqw50qiSBVyTLg4w4QQ25qmtRgkwHntIcwJ0Uk47TmVbVIP7yQbsIcfW5VVgm6DIrQrHr_tKK_pTzOLwuqrcDEkFKEThk7PUwgF2idIlgtm6L-2ZTsJC-cj_D_e_4A13PDGA
CitedBy_id crossref_primary_10_1039_D3NH00491K
crossref_primary_10_1016_j_colcom_2021_100438
crossref_primary_10_1007_s11664_022_09826_x
crossref_primary_10_1002_smll_202007073
crossref_primary_10_2174_1381612826666191219130033
crossref_primary_10_3390_nano8090641
crossref_primary_10_3389_fimmu_2023_1265751
crossref_primary_10_1016_j_jksus_2022_101989
crossref_primary_10_1007_s11696_023_02851_y
crossref_primary_10_1021_acs_chemrestox_9b00368
crossref_primary_10_1016_j_jddst_2020_102018
crossref_primary_10_2174_1389201023666220803150431
crossref_primary_10_1016_j_biopha_2018_11_122
crossref_primary_10_1002_cplu_202400420
crossref_primary_10_1021_acsomega_4c03055
crossref_primary_10_3390_nano14221854
crossref_primary_10_1021_acsnano_0c09563
crossref_primary_10_3390_cancers13215424
crossref_primary_10_1007_s10787_022_01104_w
crossref_primary_10_1007_s11356_022_21235_5
crossref_primary_10_1016_j_ijpharm_2019_118561
crossref_primary_10_1177_1559325820912154
crossref_primary_10_3390_ijms20246358
crossref_primary_10_1039_D0EN00963F
crossref_primary_10_3389_fbioe_2019_00447
crossref_primary_10_1186_s13287_018_0954_6
crossref_primary_10_1016_j_colsurfa_2019_123791
crossref_primary_10_1016_j_sjbs_2021_01_008
crossref_primary_10_3390_nano8100761
crossref_primary_10_1021_acsomega_4c05102
crossref_primary_10_3390_separations8110215
crossref_primary_10_1016_j_ejmech_2020_112229
crossref_primary_10_1088_2053_1591_ab429f
crossref_primary_10_1002_ddr_21903
crossref_primary_10_1002_cnma_202400636
crossref_primary_10_3390_molecules25153363
crossref_primary_10_1021_acsomega_3c01477
crossref_primary_10_1039_C9CP02357G
crossref_primary_10_3390_cancers13215317
crossref_primary_10_3390_ma16155354
crossref_primary_10_1021_acs_bioconjchem_8b00873
crossref_primary_10_1590_1519_6984_279564
crossref_primary_10_1186_s12951_020_00591_9
crossref_primary_10_1039_D4RA04068F
crossref_primary_10_3390_encyclopedia1030046
crossref_primary_10_1016_j_inoche_2023_110686
crossref_primary_10_1021_acs_molpharmaceut_9b00470
crossref_primary_10_3390_s19102418
crossref_primary_10_3390_molecules28145519
crossref_primary_10_1080_09205063_2022_2151819
crossref_primary_10_1186_s12645_022_00143_w
crossref_primary_10_3389_fmedt_2025_1528826
crossref_primary_10_1007_s12647_021_00484_8
crossref_primary_10_1016_j_cej_2022_135304
crossref_primary_10_1038_s41368_024_00343_7
crossref_primary_10_1088_2632_959X_abc706
crossref_primary_10_3389_fbioe_2020_602021
crossref_primary_10_1039_D3SM01166F
crossref_primary_10_1007_s00210_025_03839_z
crossref_primary_10_1039_D4FO04715J
crossref_primary_10_1080_21691401_2019_1687501
crossref_primary_10_1007_s41981_024_00334_z
crossref_primary_10_54393_fbt_v4i01_65
crossref_primary_10_1002_lsm_23482
crossref_primary_10_3390_nano12203706
crossref_primary_10_1021_acsabm_2c00975
crossref_primary_10_3390_cells11142172
crossref_primary_10_2147_IJN_S404394
crossref_primary_10_3390_ma15217579
crossref_primary_10_3389_fmed_2025_1557611
crossref_primary_10_1016_j_mtadv_2021_100191
crossref_primary_10_3390_pharmaceutics15020432
crossref_primary_10_3390_pharmaceutics15020430
crossref_primary_10_1007_s12011_024_04446_4
crossref_primary_10_1016_j_msec_2021_112078
crossref_primary_10_1016_j_msec_2021_112199
crossref_primary_10_3390_molecules29245837
crossref_primary_10_3390_ijms19123877
crossref_primary_10_1039_D2NJ00636G
crossref_primary_10_1002_adhm_202001378
crossref_primary_10_1016_j_mtcomm_2022_104311
crossref_primary_10_1364_OL_486196
crossref_primary_10_1039_D1RA02172A
crossref_primary_10_1016_j_jddst_2019_06_010
crossref_primary_10_1080_10826068_2023_2245875
crossref_primary_10_1016_j_apsb_2020_10_005
crossref_primary_10_1103_PhysRevE_105_055102
crossref_primary_10_1177_1091581820938329
crossref_primary_10_3389_fbioe_2019_00398
crossref_primary_10_1016_j_semcancer_2021_11_008
crossref_primary_10_1021_acs_bioconjchem_0c00669
crossref_primary_10_1002_asia_202001202
crossref_primary_10_3390_ma13184068
crossref_primary_10_1088_2632_959X_abddd3
crossref_primary_10_3390_pharmaceutics14010070
crossref_primary_10_1016_j_ajps_2020_03_003
crossref_primary_10_1021_acs_langmuir_0c02767
crossref_primary_10_2147_IJN_S445206
crossref_primary_10_1142_S0219581X21500563
crossref_primary_10_1016_j_jtemb_2023_127286
crossref_primary_10_1186_s12951_022_01717_x
crossref_primary_10_1021_acs_biomac_9b00137
crossref_primary_10_3390_nano13091469
crossref_primary_10_3390_nano9030396
crossref_primary_10_2147_IJN_S268548
crossref_primary_10_1080_24701556_2020_1862217
crossref_primary_10_3390_molecules28104169
crossref_primary_10_3390_molecules24224145
crossref_primary_10_3390_polym15234563
crossref_primary_10_1021_acsabm_4c00835
crossref_primary_10_1021_acs_nanolett_3c01166
crossref_primary_10_1007_s12031_020_01577_w
crossref_primary_10_2147_IJN_S277014
crossref_primary_10_1039_C9RA08536J
crossref_primary_10_3390_biom10101401
crossref_primary_10_3390_polym14071405
crossref_primary_10_7717_peerj_18214
crossref_primary_10_3390_ijms22041803
crossref_primary_10_1007_s12596_024_01962_3
crossref_primary_10_1186_s40580_023_00398_y
crossref_primary_10_1016_j_msec_2019_01_068
crossref_primary_10_1080_1061186X_2021_1892121
crossref_primary_10_1038_s41598_020_66419_6
crossref_primary_10_1186_s12951_018_0392_8
crossref_primary_10_1002_adma_202305268
crossref_primary_10_3390_ph14121335
crossref_primary_10_3389_fonc_2023_1194524
crossref_primary_10_2147_IJN_S237820
crossref_primary_10_3390_molecules27092795
crossref_primary_10_1016_j_measurement_2024_114167
crossref_primary_10_1080_24701556_2021_2025077
crossref_primary_10_1002_sia_6697
crossref_primary_10_1016_j_chemosphere_2020_128306
crossref_primary_10_1016_j_jddst_2020_102070
crossref_primary_10_1007_s40291_024_00713_1
crossref_primary_10_1016_j_jare_2018_06_005
crossref_primary_10_1016_j_ijpharm_2019_118867
crossref_primary_10_1002_slct_202200884
crossref_primary_10_1016_j_jddst_2023_105174
crossref_primary_10_47583_ijpsrr_2022_v77i01_004
crossref_primary_10_1002_cac2_12255
crossref_primary_10_1007_s13404_025_00357_x
crossref_primary_10_3390_pharmaceutics14030664
crossref_primary_10_1038_s41598_024_81875_0
crossref_primary_10_3390_molecules27010146
crossref_primary_10_1016_j_apsusc_2019_03_243
crossref_primary_10_3390_gels8100655
crossref_primary_10_2174_1574885518666221129151025
crossref_primary_10_1088_2043_6262_ad6cbf
crossref_primary_10_1021_acs_biomac_1c00160
crossref_primary_10_59324_ejtas_2024_2_2__78
crossref_primary_10_1002_advs_202413253
crossref_primary_10_1021_acs_jpcb_1c05557
crossref_primary_10_3390_pharmaceutics13111795
crossref_primary_10_1080_1040841X_2020_1803208
crossref_primary_10_1016_j_jddst_2024_106495
crossref_primary_10_1007_s40005_019_00435_1
crossref_primary_10_2174_2210303113666230622123933
crossref_primary_10_2217_nnm_2018_0009
crossref_primary_10_3390_nano14050413
crossref_primary_10_2217_nnm_2018_0242
crossref_primary_10_3390_jnt4010001
crossref_primary_10_1016_j_drudis_2021_11_011
crossref_primary_10_2174_1389200221666200610173724
crossref_primary_10_1049_iet_nbt_2020_0093
crossref_primary_10_3390_nano10061107
crossref_primary_10_3390_molecules24132509
crossref_primary_10_1016_j_bbrc_2024_150043
crossref_primary_10_1016_j_jddst_2019_03_017
crossref_primary_10_3390_jcs5080219
crossref_primary_10_3390_molecules24142661
crossref_primary_10_1098_rsos_201266
crossref_primary_10_1016_j_bbrc_2025_151512
crossref_primary_10_3390_s19122700
crossref_primary_10_1134_S1061933X19020078
crossref_primary_10_4028_p_8bf786
crossref_primary_10_1021_acs_iecr_8b02526
crossref_primary_10_1002_jbio_201960103
crossref_primary_10_1016_j_ijbiomac_2023_126869
crossref_primary_10_1007_s11356_024_32439_2
crossref_primary_10_2147_IJN_S315481
crossref_primary_10_1016_j_addr_2023_114962
crossref_primary_10_2217_nnm_2018_0266
crossref_primary_10_1016_j_addr_2022_114320
crossref_primary_10_1007_s10973_020_09502_4
crossref_primary_10_1007_s10876_022_02287_6
crossref_primary_10_3390_nano12071102
crossref_primary_10_1007_s13204_023_02853_y
crossref_primary_10_1186_s11671_023_03932_3
crossref_primary_10_1039_C8CP05587D
crossref_primary_10_1134_S1068162021010222
crossref_primary_10_1016_j_ijbiomac_2022_05_025
crossref_primary_10_1016_j_envres_2023_115673
crossref_primary_10_1080_10643389_2019_1705103
crossref_primary_10_2217_nnm_2021_0265
crossref_primary_10_53964_jmn_2021001
crossref_primary_10_3390_ph16060778
crossref_primary_10_1021_acsanm_3c05161
crossref_primary_10_3389_fphar_2024_1438237
crossref_primary_10_1063_1_5139291
crossref_primary_10_1002_slct_202001230
crossref_primary_10_1172_JCI168485
crossref_primary_10_3390_jnt5020003
crossref_primary_10_32604_or_2023_042228
crossref_primary_10_2174_0929867329666220821193938
crossref_primary_10_1007_s11357_019_00116_9
crossref_primary_10_3390_biomedicines9020113
crossref_primary_10_3390_chemosensors8030080
crossref_primary_10_1016_j_ejps_2022_106279
crossref_primary_10_1155_2021_6135920
crossref_primary_10_1016_j_ijbiomac_2023_126889
crossref_primary_10_4081_jbr_2025_12674
crossref_primary_10_1080_07391102_2020_1837677
crossref_primary_10_1016_j_microc_2021_106393
crossref_primary_10_1016_j_nxmate_2024_100401
crossref_primary_10_1002_prp2_849
crossref_primary_10_1155_2018_7670505
crossref_primary_10_3390_ma12223775
crossref_primary_10_1080_08982104_2022_2086567
crossref_primary_10_1016_j_jddst_2023_104835
crossref_primary_10_3390_ijms19124031
crossref_primary_10_3390_pharmaceutics13050678
crossref_primary_10_1016_j_mrgentox_2022_503556
crossref_primary_10_4028_www_scientific_net_JNanoR_68_123
crossref_primary_10_3390_ijms20205011
crossref_primary_10_1016_j_ijpharm_2017_10_043
crossref_primary_10_1007_s12033_023_00784_1
crossref_primary_10_2139_ssrn_3883866
crossref_primary_10_1016_j_jconrel_2022_04_035
crossref_primary_10_3390_bioengineering9020061
crossref_primary_10_1016_j_onano_2025_100238
crossref_primary_10_3390_ijms24054697
crossref_primary_10_2147_IJN_S355142
crossref_primary_10_1016_j_carbpol_2021_117907
crossref_primary_10_1088_1361_6528_acdf63
crossref_primary_10_1088_2632_959X_abe473
crossref_primary_10_1186_s40580_019_0183_4
crossref_primary_10_1016_j_microc_2019_104382
crossref_primary_10_3390_life11070682
crossref_primary_10_1007_s13205_024_04086_4
crossref_primary_10_1038_s41392_023_01642_x
crossref_primary_10_14791_btrt_2022_0032
crossref_primary_10_1039_D1CS01111A
crossref_primary_10_1021_acsami_4c12063
crossref_primary_10_1002_slct_202204841
crossref_primary_10_1007_s11696_020_01465_y
crossref_primary_10_1007_s10876_022_02229_2
crossref_primary_10_1007_s00210_023_02865_z
crossref_primary_10_1021_acsbiomaterials_9b00264
crossref_primary_10_1007_s11696_022_02520_6
crossref_primary_10_1016_j_vibspec_2018_06_008
crossref_primary_10_33483_jfpau_773430
crossref_primary_10_3390_pharmaceutics14020224
crossref_primary_10_1186_s12645_022_00118_x
crossref_primary_10_1016_j_addr_2024_115481
crossref_primary_10_1021_acschemneuro_4c00766
crossref_primary_10_3390_nano10091671
crossref_primary_10_1039_D4NA00507D
crossref_primary_10_1152_ajpcell_00695_2023
crossref_primary_10_1007_s12668_023_01065_6
crossref_primary_10_1007_s41939_025_00830_2
crossref_primary_10_1002_wnan_1619
crossref_primary_10_1016_j_pdpdt_2020_101846
crossref_primary_10_1021_acsami_0c17121
crossref_primary_10_3390_cancers16234007
crossref_primary_10_3390_pharmaceutics11110551
crossref_primary_10_32948_ajo_2022_12_31
crossref_primary_10_3390_polym14061188
crossref_primary_10_1016_j_apradiso_2025_111671
crossref_primary_10_3390_ijms19071979
crossref_primary_10_1080_14328917_2020_1825770
crossref_primary_10_47262_BL_7_2_20210617
crossref_primary_10_1186_s40824_018_0120_3
crossref_primary_10_1016_j_onano_2021_100033
crossref_primary_10_1021_acsanm_3c06070
crossref_primary_10_1002_asia_202400616
crossref_primary_10_1016_j_scitotenv_2024_173763
crossref_primary_10_1080_00032719_2017_1423077
crossref_primary_10_1186_s12989_019_0307_3
crossref_primary_10_3390_app10113824
crossref_primary_10_5812_amh_112274
crossref_primary_10_1016_j_talanta_2025_127737
crossref_primary_10_3390_molecules26154585
crossref_primary_10_1021_acs_langmuir_2c01122
crossref_primary_10_1021_jacs_3c14079
crossref_primary_10_3390_nano12132144
crossref_primary_10_3762_bjnano_15_4
crossref_primary_10_1021_acsanm_0c01785
crossref_primary_10_1021_acs_langmuir_2c03429
crossref_primary_10_1070_RCR4843
crossref_primary_10_1016_j_inoche_2024_113886
crossref_primary_10_1016_j_msec_2020_111337
crossref_primary_10_3390_nano10122474
crossref_primary_10_3390_pharmaceutics13111933
crossref_primary_10_1016_j_arabjc_2024_105948
crossref_primary_10_1021_acsomega_3c08459
crossref_primary_10_3390_molecules26082380
crossref_primary_10_1016_j_jddst_2019_101152
crossref_primary_10_1134_S0036024419130065
crossref_primary_10_1002_nano_202100255
crossref_primary_10_1007_s11033_023_08823_5
crossref_primary_10_1016_j_arabjc_2020_05_010
crossref_primary_10_1016_j_biopha_2021_111753
crossref_primary_10_3390_nu15143136
crossref_primary_10_1016_j_jddst_2023_104729
crossref_primary_10_3390_pharmaceutics13111940
crossref_primary_10_1039_D2MA01075E
crossref_primary_10_1021_acs_langmuir_2c01137
crossref_primary_10_1155_2024_8846112
crossref_primary_10_1016_j_colsurfa_2018_11_052
crossref_primary_10_1002_app_55146
crossref_primary_10_1016_j_compbiolchem_2021_107595
crossref_primary_10_1021_acs_molpharmaceut_3c00478
crossref_primary_10_2217_fon_2020_0198
crossref_primary_10_1021_acs_cgd_4c01687
crossref_primary_10_1016_j_rechem_2024_101559
crossref_primary_10_1016_j_apmt_2021_101156
crossref_primary_10_1016_j_micpath_2024_106575
crossref_primary_10_3390_pharmaceutics14020397
crossref_primary_10_3390_nano13061130
crossref_primary_10_3390_gels4020055
crossref_primary_10_1155_2019_3702518
crossref_primary_10_1016_j_colsurfb_2022_112828
crossref_primary_10_18466_cbayarfbe_1338606
crossref_primary_10_3390_pharmaceutics14050909
crossref_primary_10_3390_ijerph16193617
crossref_primary_10_1021_acs_jpcc_9b03086
crossref_primary_10_1016_j_ijpharm_2020_119729
crossref_primary_10_3390_cells12121637
crossref_primary_10_1007_s10876_019_01661_1
crossref_primary_10_22159_ijap_2023v15i4_47401
crossref_primary_10_1016_j_jmrt_2020_10_021
crossref_primary_10_1016_j_optlastec_2024_111218
crossref_primary_10_1016_j_apsusc_2020_147615
crossref_primary_10_1016_j_physb_2025_417018
crossref_primary_10_1016_j_carbpol_2020_116735
crossref_primary_10_1002_aic_16993
crossref_primary_10_1016_j_inoche_2023_110858
crossref_primary_10_3390_molecules23081848
crossref_primary_10_1515_nanoph_2018_0226
crossref_primary_10_1088_1361_6528_abbfd5
crossref_primary_10_3390_nano11020312
crossref_primary_10_1016_j_jer_2024_09_011
crossref_primary_10_2174_1874467213666200730114943
crossref_primary_10_1155_2023_3861758
crossref_primary_10_1080_10667857_2021_1905206
crossref_primary_10_3390_pathogens12060838
crossref_primary_10_1111_lam_13082
crossref_primary_10_19161_etd_698596
crossref_primary_10_1002_cbdv_202200342
crossref_primary_10_3390_pharmaceutics13122070
crossref_primary_10_1021_acs_langmuir_8b02616
crossref_primary_10_7759_cureus_52130
crossref_primary_10_1016_j_ijpharm_2020_119514
crossref_primary_10_1016_j_micpath_2023_106499
crossref_primary_10_15625_2525_2518_16892
crossref_primary_10_1515_ntrev_2022_0153
crossref_primary_10_1016_j_talanta_2024_126790
crossref_primary_10_1021_jacs_9b13813
crossref_primary_10_1016_j_mrrev_2021_108385
crossref_primary_10_3390_pharmaceutics16020251
crossref_primary_10_4028_www_scientific_net_KEM_772_78
crossref_primary_10_7759_cureus_37803
crossref_primary_10_1007_s13205_021_03105_y
crossref_primary_10_3390_nano13172401
crossref_primary_10_3390_ph15111362
crossref_primary_10_1007_s13204_021_01900_w
crossref_primary_10_47262_SL_10_2_132022090
crossref_primary_10_3390_mi14112068
crossref_primary_10_3390_pr10020426
crossref_primary_10_1208_s12249_024_02968_7
crossref_primary_10_3390_ijms23147597
crossref_primary_10_1016_j_jddst_2022_103280
crossref_primary_10_1097_CNQ_0000000000000185
crossref_primary_10_1088_1361_6528_ab72b4
crossref_primary_10_1002_smsc_202400095
crossref_primary_10_1016_j_biomaterials_2021_120682
crossref_primary_10_1039_C9TB02924A
crossref_primary_10_3390_ma15030875
crossref_primary_10_1021_acsabm_3c01064
crossref_primary_10_3390_cancers13061278
crossref_primary_10_1080_1061186X_2022_2164290
crossref_primary_10_1103_PhysRevE_104_015102
crossref_primary_10_1021_acs_bioconjchem_4c00589
crossref_primary_10_1016_j_jddst_2020_101516
crossref_primary_10_1155_2021_1566834
crossref_primary_10_1016_j_biomaterials_2024_123029
Cites_doi 10.1021/jp045070x
10.1016/j.taap.2016.01.005
10.1021/ja015556g
10.1016/j.biomaterials.2011.10.052
10.1039/c2an35734h
10.1002/cjoc.201500839
10.1021/mp060132k
10.1016/j.nano.2007.07.001
10.1002/adma.201300081
10.1016/j.biomaterials.2013.12.100
10.1021/nn200007z
10.1126/science.1125559
10.1002/anie.200504599
10.1016/j.biomaterials.2012.09.054
10.1021/nl034396z
10.1021/ja046572r
10.1007/s12274-014-0697-3
10.1021/ja801631c
10.1259/bjr/13169882
10.1016/j.taap.2009.03.009
10.1016/j.biomaterials.2014.05.094
10.1021/la301387p
10.1021/nl300027p
10.1039/C6SC03631G
10.1021/bc800469g
10.1155/2016/4964693
10.1002/adhm.201200370
10.1038/gt.2011.95
10.1016/j.talanta.2011.08.028
10.1016/j.biomaterials.2011.01.001
10.3390/ma9060406
10.1016/j.msec.2015.05.013
10.1038/357455a0
10.2147/nano.2006.1.1.51
10.1021/ja908117a
10.1111/j.1747-0285.2005.00324.x
10.1016/j.biomaterials.2014.11.053
10.1007/s11671-007-9104-2
10.1016/j.snb.2016.05.131
10.3390/polym8040156
10.1021/ja400150v
10.1016/S1359-6446(02)02255-9
10.1016/j.biotechadv.2012.10.002
10.1007/s00204-014-1245-3
10.2174/1568009611313040002
10.1021/nn901877h
10.1039/c3nr33403a
10.1016/j.jconrel.2005.12.022
10.1016/j.biomaterials.2012.11.010
10.1021/cm020732l
10.1073/pnas.0901715106
10.1016/j.jconrel.2015.04.007
10.1016/j.addr.2016.02.010
10.3389/fimmu.2017.00239
10.1016/j.ymeth.2014.02.006
10.4172/2155-983X.1000e139
10.1039/C6TB01131D
10.1016/j.msec.2016.04.030
10.1016/j.electacta.2011.08.018
10.1016/j.biomaterials.2014.04.005
10.1007/s11095-007-9257-9
10.1002/adhm.201300577
10.1016/j.addr.2008.03.016
ContentType Journal Article
Copyright Copyright MDPI AG 2017
2017 by the authors. 2017
Copyright_xml – notice: Copyright MDPI AG 2017
– notice: 2017 by the authors. 2017
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7X7
7XB
88E
8FI
8FJ
8FK
ABUWG
AFKRA
AZQEC
BENPR
CCPQU
DWQXO
FYUFA
GHDGH
K9.
M0S
M1P
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
7X8
5PM
DOA
DOI 10.3390/molecules22091445
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
ProQuest Central (Corporate)
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials
ProQuest Central
ProQuest One Community College
ProQuest Central Korea
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Health & Medical Complete (Alumni)
ProQuest Health & Medical Collection
Proquest Medical Database
ProQuest Central Premium
ProQuest One Academic
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Publicly Available Content Database
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Central China
ProQuest Central
ProQuest Health & Medical Research Collection
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Health & Medical Research Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest Hospital Collection (Alumni)
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
ProQuest One Academic
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList CrossRef
MEDLINE - Academic
Publicly Available Content Database
MEDLINE


Database_xml – sequence: 1
  dbid: DOA
  name: Directory of Open Access Journals (DOAJ)
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 4
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Chemistry
EISSN 1420-3049
ExternalDocumentID oai_doaj_org_article_f92666eed94c48b4bcd20503a5b0a110
PMC6151763
28858253
10_3390_molecules22091445
Genre Journal Article
Review
GroupedDBID ---
0R~
123
2WC
53G
5VS
7X7
88E
8FE
8FG
8FH
8FI
8FJ
A8Z
AADQD
AAFWJ
AAHBH
AAYXX
ABDBF
ABUWG
ACGFO
ACIWK
ACPRK
ACUHS
AEGXH
AENEX
AFKRA
AFPKN
AFRAH
AFZYC
AIAGR
ALIPV
ALMA_UNASSIGNED_HOLDINGS
BENPR
BPHCQ
BVXVI
CCPQU
CITATION
CS3
D1I
DIK
DU5
E3Z
EBD
EMOBN
ESX
FYUFA
GROUPED_DOAJ
GX1
HH5
HMCUK
HYE
HZ~
I09
IHR
IPNFZ
KQ8
LK8
M1P
MODMG
O-U
O9-
OK1
P2P
PHGZM
PHGZT
PIMPY
PQQKQ
PROAC
PSQYO
RIG
RPM
SV3
TR2
TUS
UKHRP
~8M
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7XB
8FK
AZQEC
DWQXO
K9.
PJZUB
PKEHL
PPXIY
PQEST
PQUKI
PRINS
7X8
5PM
PUEGO
ID FETCH-LOGICAL-c559t-343e70e669127e9594c6489904d2215f5f92c81dfc3595d51e9402ae2bcfe5ce3
IEDL.DBID 7X7
ISSN 1420-3049
IngestDate Wed Aug 27 01:20:12 EDT 2025
Thu Aug 21 18:10:26 EDT 2025
Fri Jul 11 11:14:23 EDT 2025
Fri Jul 25 19:46:43 EDT 2025
Thu Apr 03 07:01:34 EDT 2025
Thu Apr 24 22:52:08 EDT 2025
Tue Jul 01 03:11:39 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 9
Keywords disease diagnosis
drug delivery
molecular nanoprobes
gold nanoparticles
imaging
Language English
License https://creativecommons.org/licenses/by/4.0
Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c559t-343e70e669127e9594c6489904d2215f5f92c81dfc3595d51e9402ae2bcfe5ce3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
OpenAccessLink https://www.proquest.com/docview/1952214112?pq-origsite=%requestingapplication%
PMID 28858253
PQID 1952214112
PQPubID 2032355
ParticipantIDs doaj_primary_oai_doaj_org_article_f92666eed94c48b4bcd20503a5b0a110
pubmedcentral_primary_oai_pubmedcentral_nih_gov_6151763
proquest_miscellaneous_1934284773
proquest_journals_1952214112
pubmed_primary_28858253
crossref_citationtrail_10_3390_molecules22091445
crossref_primary_10_3390_molecules22091445
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 20170831
PublicationDateYYYYMMDD 2017-08-31
PublicationDate_xml – month: 8
  year: 2017
  text: 20170831
  day: 31
PublicationDecade 2010
PublicationPlace Switzerland
PublicationPlace_xml – name: Switzerland
– name: Basel
PublicationTitle Molecules (Basel, Switzerland)
PublicationTitleAlternate Molecules
PublicationYear 2017
Publisher MDPI AG
MDPI
Publisher_xml – name: MDPI AG
– name: MDPI
References Wang (ref_61) 2011; 32
Shenoy (ref_18) 2006; 1
Sousa (ref_31) 2014; 35
Li (ref_47) 2014; 3
Miller (ref_21) 1992; 357
Jing (ref_59) 2014; 35
Brown (ref_17) 2010; 132
Bhattacharya (ref_19) 2007; 3
Sun (ref_37) 2016; 4
Skirtach (ref_41) 2006; 45
Kim (ref_60) 2010; 4
Xie (ref_57) 2009; 20
Dykman (ref_39) 2017; 8
Ghosh (ref_42) 2008; 60
Wang (ref_63) 2013; 34
Xu (ref_33) 2012; 12
Guo (ref_52) 2016; 235
Gupta (ref_43) 2002; 7
Wu (ref_51) 2013; 135
Angelatos (ref_46) 2005; 109
Huefner (ref_55) 2014; 68
Ali (ref_12) 2012; 28
Verma (ref_30) 2004; 126
Liu (ref_35) 2016; 103
Kawano (ref_50) 2006; 111
Verissimo (ref_2) 2016; 65
Hainfeld (ref_4) 2005; 79
Wang (ref_7) 2016; 34
Han (ref_24) 2006; 67
Cheng (ref_49) 2008; 130
Kumar (ref_5) 2013; 31
Austin (ref_9) 2014; 88
Bhumkar (ref_29) 2007; 24
Peng (ref_62) 2012; 33
Zhao (ref_27) 2015; 54
Gu (ref_14) 2003; 3
Shiang (ref_34) 2013; 5
Indrasekara (ref_56) 2013; 2
ref_36
Wen (ref_64) 2013; 34
Lee (ref_58) 2013; 25
Kim (ref_22) 2012; 19
Nikoobakht (ref_11) 2003; 15
Kong (ref_54) 2011; 56
Rosi (ref_25) 2006; 312
Kong (ref_53) 2011; 85
Wang (ref_16) 2011; 5
Park (ref_48) 2015; 207
ref_44
Chen (ref_15) 2007; 4
Frens (ref_10) 1973; 241
ref_40
Saha (ref_13) 2007; 2
Wang (ref_45) 2014; 35
McIntosh (ref_23) 2001; 123
Bonoiu (ref_26) 2009; 106
ref_8
Demenev (ref_32) 1996; 41
Gu (ref_20) 2009; 237
Liu (ref_28) 2012; 137
Fratoddi (ref_3) 2015; 8
Zhang (ref_65) 2015; 42
Akhter (ref_1) 2013; 13
ref_6
Ilinskaya (ref_38) 2016; 299
References_xml – volume: 109
  start-page: 3071
  year: 2005
  ident: ref_46
  article-title: Light-responsive polyelectrolyte/gold nanoparticle microcapsules
  publication-title: J. Phys. Chem. B
  doi: 10.1021/jp045070x
– volume: 299
  start-page: 70
  year: 2016
  ident: ref_38
  article-title: Understanding the immunogenicity and antigenicity of nanomaterials: Past, present and future
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/j.taap.2016.01.005
– volume: 123
  start-page: 7626
  year: 2001
  ident: ref_23
  article-title: Inhibition of DNA transcription using cationic mixed monolayer protected gold clusters
  publication-title: J. Am. Chem. Soc.
  doi: 10.1021/ja015556g
– volume: 33
  start-page: 1107
  year: 2012
  ident: ref_62
  article-title: PEGylated dendrimer-entrapped gold nanoparticles for in vivo blood pool and tumor imaging by computed tomography
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2011.10.052
– volume: 137
  start-page: 3794
  year: 2012
  ident: ref_28
  article-title: Simple, sensitive and selective detection of dopamine using dithiobis (succinimidylpropionate)-modified gold nanoparticles as colorimetric probes
  publication-title: Analyst
  doi: 10.1039/c2an35734h
– volume: 34
  start-page: 299
  year: 2016
  ident: ref_7
  article-title: DNA nanotechnology mediated gold nanoparticle conjugates and their applications in biomedicine
  publication-title: Chin. J. Chem.
  doi: 10.1002/cjoc.201500839
– volume: 4
  start-page: 713
  year: 2007
  ident: ref_15
  article-title: Methotrexate conjugated to gold nanoparticles inhibits tumor growth in a syngeneic lung tumor model
  publication-title: Mol. Pharmaceut.
  doi: 10.1021/mp060132k
– volume: 241
  start-page: 20
  year: 1973
  ident: ref_10
  article-title: Controlled nucleation for the regulation of the particle size in monodisperse gold suspensions
  publication-title: Nature
– volume: 3
  start-page: 224
  year: 2007
  ident: ref_19
  article-title: Attaching folic acid on gold nanoparticles using noncovalent interaction via different polyethylene glycol backbones and targeting of cancer cells
  publication-title: Nanomed. Nanotechnol.
  doi: 10.1016/j.nano.2007.07.001
– volume: 25
  start-page: 2641
  year: 2013
  ident: ref_58
  article-title: Nano-Sized CT Contrast Agents
  publication-title: Adv. Mater.
  doi: 10.1002/adma.201300081
– volume: 35
  start-page: 3455
  year: 2014
  ident: ref_31
  article-title: Blood protein coating of gold nanoparticles as potential tool for organ targeting
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2013.12.100
– volume: 5
  start-page: 3679
  year: 2011
  ident: ref_16
  article-title: Doxorubicin-tethered responsive gold nanoparticles facilitate intracellular drug delivery for overcoming multidrug resistance in cancer cells
  publication-title: ACS Nano
  doi: 10.1021/nn200007z
– volume: 312
  start-page: 1027
  year: 2006
  ident: ref_25
  article-title: Oligonucleotide-modified gold nanoparticles for intracellular gene regulation
  publication-title: Science
  doi: 10.1126/science.1125559
– volume: 41
  start-page: 107
  year: 1996
  ident: ref_32
  article-title: Perfection of methodical approaches to designing vaccines against tick-borne encephalitis
  publication-title: Vopr. Virusol.
– volume: 45
  start-page: 4612
  year: 2006
  ident: ref_41
  article-title: Laser-induced release of encapsulated materials inside living cells
  publication-title: Angew. Chem. Int. Ed.
  doi: 10.1002/anie.200504599
– volume: 34
  start-page: 470
  year: 2013
  ident: ref_63
  article-title: Folic acid-modified dendrimer-entrapped gold nanoparticles as nanoprobes for targeted CT imaging of human lung adencarcinoma
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2012.09.054
– volume: 3
  start-page: 1261
  year: 2003
  ident: ref_14
  article-title: Presenting vancomycin on nanoparticles to enhance antimicrobial activities
  publication-title: Nano Lett.
  doi: 10.1021/nl034396z
– volume: 126
  start-page: 13987
  year: 2004
  ident: ref_30
  article-title: Tunable reactivation of nanoparticle-inhibited β-galactosidase by glutathione at intracellular concentrations
  publication-title: J. Am. Chem. Soc.
  doi: 10.1021/ja046572r
– volume: 8
  start-page: 1771
  year: 2015
  ident: ref_3
  article-title: How toxic are gold nanoparticles? The state-of-the-art
  publication-title: Nano Res.
  doi: 10.1007/s12274-014-0697-3
– volume: 130
  start-page: 10643
  year: 2008
  ident: ref_49
  article-title: Highly efficient drug delivery with gold nanoparticle vectors for in vivo photodynamic therapy of cancer
  publication-title: J. Am. Chem. Soc.
  doi: 10.1021/ja801631c
– volume: 79
  start-page: 248
  year: 2005
  ident: ref_4
  article-title: Gold nanoparticles: A new X-ray contrast agent
  publication-title: Br. J. Radiol.
  doi: 10.1259/bjr/13169882
– volume: 237
  start-page: 196
  year: 2009
  ident: ref_20
  article-title: Nuclear penetration of surface functionalized gold nanoparticles
  publication-title: Toxicol. Appl. Pharmacol.
  doi: 10.1016/j.taap.2009.03.009
– volume: 35
  start-page: 8374
  year: 2014
  ident: ref_45
  article-title: Treatment of metastatic breast cancer by combination of chemotherapy and photothermal ablation using doxorubicin-loaded DNA wrapped gold nanorods
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2014.05.094
– volume: 28
  start-page: 9807
  year: 2012
  ident: ref_12
  article-title: Synthesis and optical properties of small Au nanorods using a seedless growth technique
  publication-title: Langmuir
  doi: 10.1021/la301387p
– volume: 12
  start-page: 2003
  year: 2012
  ident: ref_33
  article-title: Surface-engineered gold nanorods: Promising DNA vaccine adjuvant for HIV-1 treatment
  publication-title: Nano Lett.
  doi: 10.1021/nl300027p
– volume: 8
  start-page: 1719
  year: 2017
  ident: ref_39
  article-title: Immunological properties of gold nanoparticles
  publication-title: Chem. Sci.
  doi: 10.1039/C6SC03631G
– volume: 20
  start-page: 768
  year: 2009
  ident: ref_57
  article-title: Nuclear targeted nanoprobe for single living cell detection by surface-enhanced Raman scattering
  publication-title: Bioconj. Chem.
  doi: 10.1021/bc800469g
– ident: ref_44
  doi: 10.1155/2016/4964693
– volume: 2
  start-page: 1370
  year: 2013
  ident: ref_56
  article-title: Dimeric gold nanoparticle assemblies as tags for SERS-based cancer detection
  publication-title: Adv. Healthc. Mater.
  doi: 10.1002/adhm.201200370
– volume: 19
  start-page: 347
  year: 2012
  ident: ref_22
  article-title: Gold nanoparticle-mediated gene delivery induces widespread changes in the expression of innate immunity genes
  publication-title: Gene Ther.
  doi: 10.1038/gt.2011.95
– volume: 85
  start-page: 2620
  year: 2011
  ident: ref_53
  article-title: A novel lable-free electrochemical immunosensor for carcinoembryonic antigen based on gold nanoparticles-thionine-reduced graphene oxide nanocomposite film modified glassy carbon electrode
  publication-title: Talanta
  doi: 10.1016/j.talanta.2011.08.028
– volume: 32
  start-page: 2979
  year: 2011
  ident: ref_61
  article-title: Computed tomography imaging of cancer cells using acetylated dendrimer-entrapped gold nanoparticles
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2011.01.001
– ident: ref_6
  doi: 10.3390/ma9060406
– volume: 54
  start-page: 142
  year: 2015
  ident: ref_27
  article-title: Gold nanorod delivery of LSD1 siRNA induces human mesenchymal stem cell differentiation
  publication-title: Mater. Sci. Eng. C
  doi: 10.1016/j.msec.2015.05.013
– volume: 357
  start-page: 455
  year: 1992
  ident: ref_21
  article-title: Human gene therapy comes of age
  publication-title: Nature
  doi: 10.1038/357455a0
– volume: 1
  start-page: 51
  year: 2006
  ident: ref_18
  article-title: Surface functionalization of gold nanoparticles using hetero-bifunctional poly (ethylene glycol) spacer for intracellular tracking and delivery
  publication-title: Int. J. Nanomed.
  doi: 10.2147/nano.2006.1.1.51
– volume: 132
  start-page: 4678
  year: 2010
  ident: ref_17
  article-title: Gold nanoparticles for the improved anticancer drug delivery of the active component of oxaliplatin
  publication-title: J. Am. Chem. Soc.
  doi: 10.1021/ja908117a
– volume: 67
  start-page: 78
  year: 2006
  ident: ref_24
  article-title: Stability of gold nanoparticle-bound DNA toward biological, physical, and chemical agents
  publication-title: Chem. Biol. Drug Des.
  doi: 10.1111/j.1747-0285.2005.00324.x
– volume: 42
  start-page: 103
  year: 2015
  ident: ref_65
  article-title: In vivo tumor-targeted dual-modal fluorescence/CT imaging using a nanoprobe co-loaded with an aggregation-induced emission dye and gold nanoparticles
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2014.11.053
– volume: 2
  start-page: 614
  year: 2007
  ident: ref_13
  article-title: In vitro structural and functional evaluation of gold nanoparticles conjugated antibiotics
  publication-title: Nanoscale Res. Lett.
  doi: 10.1007/s11671-007-9104-2
– volume: 235
  start-page: 655
  year: 2016
  ident: ref_52
  article-title: Double functional aptamer switch probes based on gold nanorods for intracellular ATP detection and targeted drugs transportation
  publication-title: Sens. Actuators B Chem.
  doi: 10.1016/j.snb.2016.05.131
– ident: ref_8
  doi: 10.3390/polym8040156
– volume: 135
  start-page: 5254
  year: 2013
  ident: ref_51
  article-title: A DNAzyme-gold nanoparticle probe for uranyl ion in living cells
  publication-title: J. Am. Chem. Soc.
  doi: 10.1021/ja400150v
– volume: 7
  start-page: 569
  year: 2002
  ident: ref_43
  article-title: Hydrogels: From controlled release to pH-responsive drug delivery
  publication-title: Drug Discov. Today
  doi: 10.1016/S1359-6446(02)02255-9
– volume: 31
  start-page: 593
  year: 2013
  ident: ref_5
  article-title: Gold nanoparticles: Emerging paradigm for targeted drug delivery system
  publication-title: Biotechnol. Adv.
  doi: 10.1016/j.biotechadv.2012.10.002
– volume: 88
  start-page: 1391
  year: 2014
  ident: ref_9
  article-title: The optical, photothermal, and facile surface chemical properties of gold and silver nanoparticles in biodiagnostics, therapy, and drug delivery
  publication-title: Arch. Toxicol.
  doi: 10.1007/s00204-014-1245-3
– volume: 13
  start-page: 362
  year: 2013
  ident: ref_1
  article-title: Nanomedicines as cancer therapeutics: Current status
  publication-title: Curr. Cancer Drug Targets
  doi: 10.2174/1568009611313040002
– volume: 4
  start-page: 3689
  year: 2010
  ident: ref_60
  article-title: A drug-loaded aptamer-gold nanoparticle bioconjugate for combined CT imaging and therapy of prostate cancer
  publication-title: ACS Nano
  doi: 10.1021/nn901877h
– volume: 5
  start-page: 2756
  year: 2013
  ident: ref_34
  article-title: Highly efficient inhibition of human immunodeficiency virus type 1 reverse transcriptase by aptamers functionalized gold nanoparticles
  publication-title: Nanoscale
  doi: 10.1039/c3nr33403a
– volume: 111
  start-page: 382
  year: 2006
  ident: ref_50
  article-title: Stabilizing of plasmid DNA in vivo by PEG-modified cationic gold nanoparticles and the gene expression assisted with electrical pulses
  publication-title: J. Control. Release
  doi: 10.1016/j.jconrel.2005.12.022
– volume: 34
  start-page: 1570
  year: 2013
  ident: ref_64
  article-title: Multifunctional dendrimer-entrapped gold nanoparticles for dual mode CT/MR imaging applications
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2012.11.010
– volume: 15
  start-page: 1957
  year: 2003
  ident: ref_11
  article-title: Preparation and growth mechanism of gold nanorods (NRs) using seed-mediated growth method
  publication-title: Chem. Mater.
  doi: 10.1021/cm020732l
– volume: 106
  start-page: 5546
  year: 2009
  ident: ref_26
  article-title: Nanotechnology approach for drug addiction therapy: Gene silencing using delivery of gold nanorod-siRNA nanoplex in dopaminergic neurons
  publication-title: Proc. Natl. Acad. Sci. USA
  doi: 10.1073/pnas.0901715106
– volume: 207
  start-page: 77
  year: 2015
  ident: ref_48
  article-title: Multifunctional hollow gold nanoparticles designed for triple combination therapy and CT imaging
  publication-title: J. Control. Release
  doi: 10.1016/j.jconrel.2015.04.007
– volume: 103
  start-page: 76
  year: 2016
  ident: ref_35
  article-title: Role of nanotechnology in HIV/AIDS vaccine development
  publication-title: Adv. Drug Deliv. Rev.
  doi: 10.1016/j.addr.2016.02.010
– ident: ref_40
  doi: 10.3389/fimmu.2017.00239
– volume: 68
  start-page: 354
  year: 2014
  ident: ref_55
  article-title: Gold nanoparticles explore cells: Cellular uptake and their use as intracellular probes
  publication-title: Methods
  doi: 10.1016/j.ymeth.2014.02.006
– ident: ref_36
  doi: 10.4172/2155-983X.1000e139
– volume: 4
  start-page: 5496
  year: 2016
  ident: ref_37
  article-title: Nanomaterial-based vaccine adjuvants
  publication-title: J. Mater. Chem. B
  doi: 10.1039/C6TB01131D
– volume: 65
  start-page: 199
  year: 2016
  ident: ref_2
  article-title: In vitro cytotoxicity and phototoxicity of surface-modified gold nanoparticles associated with neutral red as a potential drug delivery system in phototherapy
  publication-title: Mater. Sci. Eng. C
  doi: 10.1016/j.msec.2016.04.030
– volume: 56
  start-page: 9386
  year: 2011
  ident: ref_54
  article-title: Gold nanoparticle/DNA/methylene blue nanocomposites for the ultrasensitive electrochemical detection of carcinoembryonic antigen
  publication-title: Electrochim. Acta
  doi: 10.1016/j.electacta.2011.08.018
– volume: 35
  start-page: 5814
  year: 2014
  ident: ref_59
  article-title: Prussian blue coated gold nanoparticles for simultaneous photoacoustic/CT bimodal imaging and photothermal ablation of cancer
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2014.04.005
– volume: 24
  start-page: 1415
  year: 2007
  ident: ref_29
  article-title: Chitosan reduced gold nanoparticles as novel carriers for transmucosal delivery of insulin
  publication-title: Pharm. Res.
  doi: 10.1007/s11095-007-9257-9
– volume: 3
  start-page: 1475
  year: 2014
  ident: ref_47
  article-title: Functional core/shell drug nanoparticles for highly effective synergistic cancer therapy
  publication-title: Adv. Healthc. Mater.
  doi: 10.1002/adhm.201300577
– volume: 60
  start-page: 1307
  year: 2008
  ident: ref_42
  article-title: Gold nanoparticles in delivery applications
  publication-title: Adv. Drug Delive. Rev.
  doi: 10.1016/j.addr.2008.03.016
SSID ssj0021415
Score 2.6397793
SecondaryResourceType review_article
Snippet Nanotechnology has become more and more potentially used in diagnosis or treatment of diseases. Advances in nanotechnology have led to new and improved...
SourceID doaj
pubmedcentral
proquest
pubmed
crossref
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
Enrichment Source
StartPage 1445
SubjectTerms Animals
disease diagnosis
Drug Carriers - administration & dosage
Drug Carriers - chemistry
drug delivery
Gold - administration & dosage
Gold - chemistry
gold nanoparticles
Humans
imaging
Metal Nanoparticles - administration & dosage
Metal Nanoparticles - chemistry
molecular nanoprobes
Molecular Probes - administration & dosage
Molecular Probes - chemistry
Nanomaterials
Nanoparticles
Nanotechnology
Optical Imaging
Quantum dots
Review
Staining and Labeling
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV09T8MwELVQF1gQ3wQKMhITImpjO0kzlpZSGBhQK7pFsXMBpDZF_Rj499w5adUCgoU1diTnfPa7F5_fMXZpPDrcCaQLiDWuiiBwSYXclTLVDU365pnNtngMun31MPAHK6W-KCeskAcuDFfLIoSQAHfySBnV0EqbVJCGSeLreuIVl6sQ8xZkqqRaHuJScYYpkdTXRkWpWZgK6qvo7tIKClmx_p8izK-JkivI09lh22XIyJvFUHfZBuR7bLO1qNS2z577VoWVP5E4Ex9n_G48TDnum0iIy7w3_pbz9mT-wtswpEyMj2veszngiFw8yVN-P7Llinhz5UD7gPU7t71W1y0LJrgGicHMlUpCWIcgiDwRQuSjyQKFhKquUoHQnvloTIMBamboOm7qexAhfUxAaJOBb0Aesko-zuGYcZWR7o1GeNMhYn6YQBAimzUU_ghpwGH1hQFjU6qJU1GLYYysgmwef7O5w66Wr7wXUhq_db6hWVl2JBVs-wB9Iy5tF__lGw6rLuY0LpfmNPYiDDnRPzzhsItlM84YnZQkOYzn1Ecqwu1QOuyocIHlSESj4SOtxpZwzTnWhrrekr-9WuFuih5xPz_5j287ZVuCIgz7e7vKKrPJHM4wPprpc7sUPgGyFw5n
  priority: 102
  providerName: Directory of Open Access Journals
Title Unique Roles of Gold Nanoparticles in Drug Delivery, Targeting and Imaging Applications
URI https://www.ncbi.nlm.nih.gov/pubmed/28858253
https://www.proquest.com/docview/1952214112
https://www.proquest.com/docview/1934284773
https://pubmed.ncbi.nlm.nih.gov/PMC6151763
https://doaj.org/article/f92666eed94c48b4bcd20503a5b0a110
Volume 22
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LTxsxEB4VOMCl6gu6LY2M1FPVFVnb-zpVvALlgCpERG6rtXeWIoVdmseh_74zXickbcUlh9iRvOOJ5_s8s98AfLYRJ3cSFSLFmlDnmISsQh4qVZnMsL557aotrpKLob4cxSN_4Tb1ZZWLM9Ed1FVr-Y78MMoJKUSa4MG3x18hd43i7KpvobEBWyxdxl6djp4IF02Pu0ymImp_-NA1nMWplBQlNb_BtBKLnGT__3Dm3-WSK_Fn8ApeeuAojrqdfg0vsHkD2yeLfm1v4XbotFjFNUs0ibYW5-24EnR6Ei321W_ivhGnk_mdOMUx12P8_ipuXCU4xS9RNpX4_uCaFomjlbT2OxgOzm5OLkLfNiG0RA9modIK0z4mSR7JFMkq2iaaaFVfV2TBuI7rXFqCqbXll3KrOMKcSGSJ0tgaY4tqFzabtsH3IHTN6jeGgpxJKfKnJSYpcVrLIEgqiwH0FwYsrNcU59YW44K4Bdu8-MfmAXxZ_uSxE9R4bvIx78pyImthuy_ayV3hbVfQ4xAHo1hPD6ozo42tJKvclLHpl4RuAthf7Gnh_6DT4smdAjhYDtOOcb6kbLCd8xylOXqnKoC9zgWWK5FZFhO5ppF0zTnWlro-0tz_dPLdjCHpVP_w_LI-wo5kBOGur_dhczaZ4yfCPzPTc05On9ngvAdbx2dXP6577i7hD3bHCU4
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB6VcigXxJuUAkaCCyJq4keyOSBUumx3aekB7YreQuw4pdI2afch1D_Fb2TGebALqLdeYydxxhPPN57xNwCvTUjBnUj4Fm2NLxMb-cRC7guR654mfvPCZVscR8OJ_HyiTjbgV3sWhtIq2zXRLdR5ZWiPfDdMECmEEuHBh4tLn6pGUXS1LaFRq8WhvfqJLtv8_aiP8_uG88Gn8f7Qb6oK-AbR88IXUtg4sFGUhDy2iUqkiSR6HYHM8QWqUEXCDaK4wtCZ1VyFNkEfK7Ncm8IqYwU-9xbclgItOZ1MHxx0Dh4OT9WRU2wMds_rArd2zjlaZUknplZsnysR8D9c-3d65oq9G9yDuw1QZXu1Zt2HDVs-gK39tj7cQ_g2cdyv7CtRQrGqYAfVNGe4WqMb3mTbsbOS9WfLU9a3U8r_uHrHxi7zHO0ly8qcjc5dkSS2txJGfwSTGxHoY9gsq9I-BSYLYtvRaFR1jEgjzmwUow9tCHRxYawHQSvA1DQc5lRKY5qiL0MyT_-RuQdvu1suagKP6zp_pFnpOhL3trtQzU7TRnYpfg76fIgt8ENlT0ttck6sOpnSQYZoyoOddk7TZkGYp3_U14NXXTPOGMVnstJWS-ojJKGFWHjwpFaBbiS811PozGNLvKYca0NdbynPfji6cMKsaEW2rx_WS9gajr8cpUej48NncIcTenFb5zuwuZgt7XPEXgv9wik8g-83_Yf9BlUOQac
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9NAEB6VVAIuqLwNbVkkuCCs2Puw40OF2qahoSiqqkb05nrX61IptUseQv1r_Dpm_CIB1Fuv3k28nh3vfJ939huAd8anzZ1AuBZjjSsjG7ikQu4KkeqeJn3zrMy2GAWHY_nlTJ2twa_mLAylVTZrYrlQp4Whb-RdP0Kk4EuEB92sTos47g8-Xf9wqYIU7bQ25TQqFzmyNz-Rvs12hn2c6_ecDw5O9w_dusKAaxBJz10hhQ09GwSRz0MbqUiaQCID8WSKN1OZyiJuENFlhs6vpsq3EfKtxHJtMquMFfi_92A9JFbUgfW9g9HxSUv3cLCq2kcVIvK6V1W5WzvjHGO0pPNTS5GwLBjwP5T7d7LmUvQbbMCjGray3crPHsOazZ_Ag_2mWtxT-DYulWDZCQlEsSJjn4tJynDtRlJe596xy5z1p4sL1rcTyga5-chOyzx0jJ4syVM2vCpLJrHdpU31ZzC-E5M-h05e5PYlMJmR9o7GEKvRwkGY2CBERm0IgnFhrANeY8DY1IrmVFhjEiOzIZvH_9jcgQ_tT64rOY_bOu_RrLQdSYm7vFBML-LadjE-DjJARBr4oLKnpTYpJ42dRGkvQWzlwGYzp3G9PMziP87swNu2GWeMdmuS3BYL6iMkYYdQOPCicoF2JLzXU0jtsSVccY6Voa625JffS_FwQrAYU17dPqw3cB_frvjrcHT0Gh5ygjLld_RN6MynC7uFQGyut2uPZ3B-1y_Zb400Rzk
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Unique+Roles+of+Gold+Nanoparticles+in+Drug+Delivery%2C+Targeting+and+Imaging+Applications&rft.jtitle=Molecules+%28Basel%2C+Switzerland%29&rft.au=Fen-Ying+Kong&rft.au=Jin-Wei%2C+Zhang&rft.au=Rong-Fang%2C+Li&rft.au=Zhong-Xia%2C+Wang&rft.date=2017-08-31&rft.pub=MDPI+AG&rft.eissn=1420-3049&rft.volume=22&rft.issue=9&rft.spage=1445&rft_id=info:doi/10.3390%2Fmolecules22091445&rft.externalDBID=HAS_PDF_LINK
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1420-3049&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1420-3049&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1420-3049&client=summon