Unique Roles of Gold Nanoparticles in Drug Delivery, Targeting and Imaging Applications
Nanotechnology has become more and more potentially used in diagnosis or treatment of diseases. Advances in nanotechnology have led to new and improved nanomaterials in biomedical applications. Common nanomaterials applicable in biomedical applications include liposomes, polymeric micelles, graphene...
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Published in | Molecules (Basel, Switzerland) Vol. 22; no. 9; p. 1445 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Switzerland
MDPI AG
31.08.2017
MDPI |
Subjects | |
Online Access | Get full text |
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Abstract | Nanotechnology has become more and more potentially used in diagnosis or treatment of diseases. Advances in nanotechnology have led to new and improved nanomaterials in biomedical applications. Common nanomaterials applicable in biomedical applications include liposomes, polymeric micelles, graphene, carbon nanotubes, quantum dots, ferroferric oxide nanoparticles, gold nanoparticles (Au NPs), and so on. Among them, Au NPs have been considered as the most interesting nanomaterial because of its unique optical, electronic, sensing and biochemical properties. Au NPs have been potentially applied for medical imaging, drug delivery, and tumor therapy in the early detection, diagnosis, and treatment of diseases. This review focuses on some recent advances in the use of Au NPs as drug carriers for the intracellular delivery of therapeutics and as molecular nanoprobes for the detection and monitoring of target molecules. |
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AbstractList | Nanotechnology has become more and more potentially used in diagnosis or treatment of diseases. Advances in nanotechnology have led to new and improved nanomaterials in biomedical applications. Common nanomaterials applicable in biomedical applications include liposomes, polymeric micelles, graphene, carbon nanotubes, quantum dots, ferroferric oxide nanoparticles, gold nanoparticles (Au NPs), and so on. Among them, Au NPs have been considered as the most interesting nanomaterial because of its unique optical, electronic, sensing and biochemical properties. Au NPs have been potentially applied for medical imaging, drug delivery, and tumor therapy in the early detection, diagnosis, and treatment of diseases. This review focuses on some recent advances in the use of Au NPs as drug carriers for the intracellular delivery of therapeutics and as molecular nanoprobes for the detection and monitoring of target molecules. Nanotechnology has become more and more potentially used in diagnosis or treatment of diseases. Advances in nanotechnology have led to new and improved nanomaterials in biomedical applications. Common nanomaterials applicable in biomedical applications include liposomes, polymeric micelles, graphene, carbon nanotubes, quantum dots, ferroferric oxide nanoparticles, gold nanoparticles (Au NPs), and so on. Among them, Au NPs have been considered as the most interesting nanomaterial because of its unique optical, electronic, sensing and biochemical properties. Au NPs have been potentially applied for medical imaging, drug delivery, and tumor therapy in the early detection, diagnosis, and treatment of diseases. This review focuses on some recent advances in the use of Au NPs as drug carriers for the intracellular delivery of therapeutics and as molecular nanoprobes for the detection and monitoring of target molecules.Nanotechnology has become more and more potentially used in diagnosis or treatment of diseases. Advances in nanotechnology have led to new and improved nanomaterials in biomedical applications. Common nanomaterials applicable in biomedical applications include liposomes, polymeric micelles, graphene, carbon nanotubes, quantum dots, ferroferric oxide nanoparticles, gold nanoparticles (Au NPs), and so on. Among them, Au NPs have been considered as the most interesting nanomaterial because of its unique optical, electronic, sensing and biochemical properties. Au NPs have been potentially applied for medical imaging, drug delivery, and tumor therapy in the early detection, diagnosis, and treatment of diseases. This review focuses on some recent advances in the use of Au NPs as drug carriers for the intracellular delivery of therapeutics and as molecular nanoprobes for the detection and monitoring of target molecules. |
Author | Kong, Fen-Ying Li, Rong-Fang Wang, Wei Wang, Wen-Juan Zhang, Jin-Wei Wang, Zhong-Xia |
AuthorAffiliation | School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, China; kongfy@ycit.edu.cn (F.-Y.K.); zhangjinwei18@163.com (J.-W.Z.); Lirongfang2324@163.com (R.-F.L.); wangzx198411@163.com (Z.-X.W.); wwj@ycit.edu.cn (W.-J.W.) |
AuthorAffiliation_xml | – name: School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, China; kongfy@ycit.edu.cn (F.-Y.K.); zhangjinwei18@163.com (J.-W.Z.); Lirongfang2324@163.com (R.-F.L.); wangzx198411@163.com (Z.-X.W.); wwj@ycit.edu.cn (W.-J.W.) |
Author_xml | – sequence: 1 givenname: Fen-Ying surname: Kong fullname: Kong, Fen-Ying – sequence: 2 givenname: Jin-Wei surname: Zhang fullname: Zhang, Jin-Wei – sequence: 3 givenname: Rong-Fang surname: Li fullname: Li, Rong-Fang – sequence: 4 givenname: Zhong-Xia surname: Wang fullname: Wang, Zhong-Xia – sequence: 5 givenname: Wen-Juan surname: Wang fullname: Wang, Wen-Juan – sequence: 6 givenname: Wei surname: Wang fullname: Wang, Wei |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28858253$$D View this record in MEDLINE/PubMed |
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SubjectTerms | Animals disease diagnosis Drug Carriers - administration & dosage Drug Carriers - chemistry drug delivery Gold - administration & dosage Gold - chemistry gold nanoparticles Humans imaging Metal Nanoparticles - administration & dosage Metal Nanoparticles - chemistry molecular nanoprobes Molecular Probes - administration & dosage Molecular Probes - chemistry Nanomaterials Nanoparticles Nanotechnology Optical Imaging Quantum dots Review Staining and Labeling |
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Title | Unique Roles of Gold Nanoparticles in Drug Delivery, Targeting and Imaging Applications |
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