A Review of Analytical Methods for Codeine Determination

• Published in: Molecules (Basel, Switzerland) Vol. 26; no. 4; p. 800
• Main Authors: Pratiwi, Rimadani, Noviana, Eka, Fauziati, Rizky, Carrão, Daniel Blascke, Gandhi, Firas Adinda, Majid, Mutiara Aini, Saputri, Febrina Amelia
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 04.02.2021; MDPI
• Subjects: Acids; Analgesics; Chemistry Techniques, Analytical - methods; chromatography; codeine; Codeine - analysis; Codeine - chemistry; Color; colorimetry; drug analysis; electrochemistry; Humans; Morphine; Multivariate analysis; Narcotics; Pain; Pharmaceuticals; Reagents; Review; spectrophotometry; codeine; colorimetry; spectrophotometry; capillary electromigration; electrochemistry; drug analysis; chromatography

Codeine is derived from morphine, an opioid analgesic, and has weaker analgesic and sedative effects than the parent molecule. This weak opioid is commonly used in combination with other drugs for over-the-counter cough relief medication. Due to the psychoactive properties of opioid drugs, the easil...