Celiac Disease Diagnosis: Simple Rules Are Better Than Complicated Algorithms

• Published in: The American journal of medicine Vol. 123; no. 8; pp. 691 - 693
• Main Authors: Catassi, Carlo, Fasano, Alessio
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.08.2010; Elsevier; Elsevier Sequoia S.A
• Subjects: Algorithm; Algorithms; Autoantibodies - analysis; Biological and medical sciences; Biopsy; Celiac disease; Celiac Disease - diagnosis; Celiac Disease - genetics; Celiac Disease - immunology; Celiac Disease - pathology; Diagnosis; Gastroenterology. Liver. Pancreas. Abdomen; General aspects; HLA Antigens - analysis; Humans; Internal Medicine; Intestinal biopsy; Intestinal Mucosa - pathology; Medical diagnosis; Medical sciences; Medical treatment; Other diseases. Semiology; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; Celiac disease; Diagnosis; Intestinal biopsy; Algorithm; Medicine; Immunopathology; Intestinal malabsorption; Digestive diseases; Intestinal disease; Complication; Coeliac disease; Decision tree

Celiac disease is the only treatable autoimmune disease, provided that a correct diagnosis is achieved and a strict, lifelong gluten-free diet is implemented. The current diagnostic algorithm for celiac disease includes initial screening serological tests, followed by a confirmatory small intestinal...