Extracellular vesicles: lipids as key components of their biogenesis and functions

• Published in: Journal of lipid research Vol. 59; no. 8; pp. 1316 - 1324
• Main Authors: Record, Michel, Silvente-Poirot, Sandrine, Poirot, Marc, Wakelam, MichaelJ.O.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2018; Journal of Lipid Research; American Society for Biochemistry and Molecular Biology; The American Society for Biochemistry and Molecular Biology; Elsevier
• Series: Thematic Review Series: Exosomes and Microvesicles: Lipids as Key Components of their Biogenesis and Functions
• Subjects: Biosynthesis; Cancer; Cell Behavior; Cell signaling; Cell-Derived Microparticles - metabolism; Cellular Biology; Cytokines; Eicosanoids; Exosomes; Exosomes - metabolism; Extracellular vesicles; Extracellular Vesicles - metabolism; Growth factors; Humans; Immunosurveillance; Life Sciences; lipid kinases; Lipid Metabolism; lipid transporters; Lipids; lipolytic enzymes; membrane asymmetry; membrane fusion; Microparticles; Phenotypes; Signal Transduction; Thematic Review Series: Exosomes and Microvesicles: Lipids as Key Components of their Biogenesis and Functions; membrane asymmetry; lipolytic enzymes; lipid kinases; lipid transporters; membrane fusion

Intercellular communication has been known for decades to involve either direct contact between cells or to operate via circulating molecules, such as cytokines, growth factors, or lipid mediators. During the last decade, we have begun to appreciate the increasing importance of intercellular communi...