Deuterostome Genomics: Lineage-Specific Protein Expansions That Enabled Chordate Muscle Evolution

• Published in: Molecular biology and evolution Vol. 35; no. 4; pp. 914 - 924
• Main Authors: Inoue, Jun, Satoh, Noriyuki
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.04.2018
• Subjects: Actin; Animals; Chordata; Chordata - genetics; Discoveries; Evolution, Molecular; Gene Duplication; Genes; Genomics; Isoforms; Larvae; Muscle contraction; Muscle Proteins - genetics; Muscles; Notochord; Orthology; Proteins; Regulatory mechanisms (biology); Troponin C; chordate evolution; muscle structural proteins; phylogenetics; lineage-specific expansion; gene duplication

Abstract Fish-like larvae were foundational to the chordate body plan, given the basal placement of free-living lancelets. That body plan probably made it possible for chordate ancestors to swim by beating a tail formed of notochord and bilateral paraxial muscles. In order to investigate the molecul...