Web-Based Independent Versus Laboratory-Based Stop-Signal Task Performance: Within-Subjects Counterbalanced Comparison Study

• Published in: Journal of medical Internet research Vol. 24; no. 5; p. e32922
• Main Authors: Poulton, Antoinette, Chen, Li Peng Evelyn, Dali, Gezelle, Fox, Michael, Hester, Robert
• Format: Journal Article
• Language: English
• Published: Canada Journal of Medical Internet Research 30.05.2022; Gunther Eysenbach MD MPH, Associate Professor; JMIR Publications
• Subjects: Accuracy; Adolescent; Adult; Alcohol; Analysis; Averages; Bayes Theorem; Bayesian analysis; Computer peripherals; Computers; Coronaviruses; COVID-19; Drug use; Feedback; Female; Generalizability; Humans; Impulsivity; Inhibition, Psychological; Internet; Keyboards; Laboratories; Male; Medical research; Original Paper; Psychology; Psychomotor Performance - physiology; Reaction time; Reaction Time - physiology; Response inhibition; Software; Statistical power; Substance abuse; Task performance; Within-subjects design; Young Adult; Stop-Signal Task; web-based assessment; cognition; inhibitory control; online assessment; response inhibition
• ISSN: 1438-8871; 1439-4456; 1438-8871
• DOI: 10.2196/32922

Considered a facet of behavioral impulsivity, response inhibition facilitates adaptive and goal-directed behavior. It is often assessed using the Stop-Signal Task (SST), which is presented on stand-alone computers under controlled laboratory conditions. Sample size may consequently be a function of cost or time and sample diversity constrained to those willing or able to attend the laboratory. Statistical power and generalizability of results might, in turn, be impacted. Such limitations may potentially be overcome via the implementation of web-based testing. The aim of this study was to investigate if there were differences between variables derived from a web-based SST when it was undertaken independently-that is, outside the laboratory, on any computer, and in the absence of researchers-versus when it was performed under laboratory conditions. We programmed a web-based SST in HTML and JavaScript and employed a counterbalanced design. A total of 166 individuals (mean age 19.72, SD 1.85, range 18-36 years; 146/166, 88% female) were recruited. Of them, 79 undertook the independent task prior to visiting the laboratory and 78 completed the independent task following their laboratory visit. The average time between SST testing was 3.72 (SD 2.86) days. Dependent samples and Bayesian paired samples t tests were used to examine differences between laboratory-based and independent SST variables. Correlational analyses were conducted on stop-signal reaction times (SSRT). After exclusions, 123 participants (mean age 19.73, SD 1.97 years) completed the SST both in the laboratory and independently. While participants were less accurate on go trials and exhibited reduced inhibitory control when undertaking the independent-compared to the laboratory-based-SST, there was a positive association between the SSRT of each condition (r=.48; P<.001; 95% CI 0.33-0.61). Findings suggest a web-based SST, which participants undertake on any computer, at any location, and in the absence of the researcher, is a suitable measure of response inhibition.