Pulmonary T-cell Lymphoma with Pulmonary Arterial Hypertension

• Published in: Internal Medicine Vol. 50; no. 16; pp. 1733 - 1736
• Main Authors: Watanabe, Satoshi, Takato, Hazuki, Waseda, Yuko, Tokuda, Akira, Katayama, Nobuyuki, Kondo, Yukio, Fujimura, Masaki, Nakao, Shinji
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 01.01.2011
• Subjects: Aged; Diagnosis, Differential; Familial Primary Pulmonary Hypertension; ground-glass opacities; Humans; Hypertension, Pulmonary - complications; Hypertension, Pulmonary - diagnosis; interlobular septal thickening; Lung Neoplasms - complications; Lung Neoplasms - diagnosis; Lymphoma, T-Cell, Peripheral - complications; Lymphoma, T-Cell, Peripheral - diagnosis; Male; peripheral T-cell lymphoma; pulmonary arterial hypertension
• ISSN: 0918-2918; 1349-7235; 1349-7235
• DOI: 10.2169/internalmedicine.50.5329

We report on a 73-year-old man with systemic lymphadenopathy and chest computed tomography (CT) findings of bilateral diffuse ground-glass opacities and interlobular septal thickening. He also had pulmonary arterial hypertension (PAH). Several lymph node biopsies were attempted, without a definitive diagnosis. A thoracoscopic lung biopsy was performed, and the specimen was diagnosed as peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS). Lymphoma cells had invaded lung vessels, resulting in PAH. We should include pulmonary lymphoma in the differential diagnosis of patients with PAH and chest CT findings of diffuse ground-glass opacities and interlobular septal thickening.