fNIRS Assessment during Cognitive Tasks in Elderly Patients with Depressive Symptoms

This study aimed to investigate differences in prefrontal cortex activation between older adults with and without depressive symptoms during cognitive tasks using functional near-infrared spectroscopy (fNIRS). We examined 204 older participants without psychiatric or neurological disorders who compl...

Full description

Saved in:
Bibliographic Details
Published inBrain sciences Vol. 13; no. 7; p. 1054
Main Authors Kang, Min-Ju, Cho, Su-Yeon, Choi, Jong-Kwan, Yang, Young-Soon
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 01.07.2023
MDPI
Subjects
Aged patients
Blood & organ donations
Cognitive ability
Communication
Cortex (frontal)
depression
Depression, Mental
fNIRS
functional near-infrared spectroscopy
geriatric depression scale
Geriatrics
Hemispheric laterality
Hemodynamics
Hemoglobin
Infrared spectroscopy
Mental depression
Mental disorders
Neurological diseases
Older people
Prefrontal cortex
Primary care
Psychological aspects
Questionnaires
Spectrum analysis
South Korea
fNIRS
depression
geriatric depression scale
functional near-infrared spectroscopy
Online AccessGet full text

Cover

Abstract This study aimed to investigate differences in prefrontal cortex activation between older adults with and without depressive symptoms during cognitive tasks using functional near-infrared spectroscopy (fNIRS). We examined 204 older participants without psychiatric or neurological disorders who completed the Geriatric Depression Scale, digit span, Verbal Fluency Test, and Stroop test. At the same time, prefrontal cortex activation was recorded using fNIRS. During the Stroop test, significantly reduced hemodynamics were observed in the depressive-symptom group. The mean accΔHbO of all channel averages was 0.14 μM in the control group and -0.75 μM in the depressive-symptom group ( = 0.03). The right hemisphere average was 0.13 μM and -0.96 μM, respectively ( = 0.02), and the left hemisphere average was 0.14 μM and -0.54 μM, respectively ( = 0.12). There was no significant difference in hemodynamic response (mean accΔHbO ) between the two groups during the digit span backward and VFT. In conclusion, reduced hemodynamics in the frontal cortex of the depressive-symptom group has been observed. The frontal fNIRS signal and the Stroop task may be used to measure depressive symptoms sensitively in the elderly.
AbstractList This study aimed to investigate differences in prefrontal cortex activation between older adults with and without depressive symptoms during cognitive tasks using functional near-infrared spectroscopy (fNIRS). We examined 204 older participants without psychiatric or neurological disorders who completed the Geriatric Depression Scale, digit span, Verbal Fluency Test, and Stroop test. At the same time, prefrontal cortex activation was recorded using fNIRS. During the Stroop test, significantly reduced hemodynamics were observed in the depressive-symptom group. The mean accΔHbO2 of all channel averages was 0.14 μM in the control group and −0.75 μM in the depressive-symptom group (p = 0.03). The right hemisphere average was 0.13 μM and −0.96 μM, respectively (p = 0.02), and the left hemisphere average was 0.14 μM and −0.54 μM, respectively (p = 0.12). There was no significant difference in hemodynamic response (mean accΔHbO2) between the two groups during the digit span backward and VFT. In conclusion, reduced hemodynamics in the frontal cortex of the depressive-symptom group has been observed. The frontal fNIRS signal and the Stroop task may be used to measure depressive symptoms sensitively in the elderly.
This study aimed to investigate differences in prefrontal cortex activation between older adults with and without depressive symptoms during cognitive tasks using functional near-infrared spectroscopy (fNIRS). We examined 204 older participants without psychiatric or neurological disorders who completed the Geriatric Depression Scale, digit span, Verbal Fluency Test, and Stroop test. At the same time, prefrontal cortex activation was recorded using fNIRS. During the Stroop test, significantly reduced hemodynamics were observed in the depressive-symptom group. The mean accΔHbO[sub.2] of all channel averages was 0.14 μM in the control group and −0.75 μM in the depressive-symptom group (p = 0.03). The right hemisphere average was 0.13 μM and −0.96 μM, respectively (p = 0.02), and the left hemisphere average was 0.14 μM and −0.54 μM, respectively (p = 0.12). There was no significant difference in hemodynamic response (mean accΔHbO[sub.2]) between the two groups during the digit span backward and VFT. In conclusion, reduced hemodynamics in the frontal cortex of the depressive-symptom group has been observed. The frontal fNIRS signal and the Stroop task may be used to measure depressive symptoms sensitively in the elderly.
This study aimed to investigate differences in prefrontal cortex activation between older adults with and without depressive symptoms during cognitive tasks using functional near-infrared spectroscopy (fNIRS). We examined 204 older participants without psychiatric or neurological disorders who completed the Geriatric Depression Scale, digit span, Verbal Fluency Test, and Stroop test. At the same time, prefrontal cortex activation was recorded using fNIRS. During the Stroop test, significantly reduced hemodynamics were observed in the depressive-symptom group. The mean accΔHbO 2 of all channel averages was 0.14 μM in the control group and −0.75 μM in the depressive-symptom group ( p = 0.03). The right hemisphere average was 0.13 μM and −0.96 μM, respectively ( p = 0.02), and the left hemisphere average was 0.14 μM and −0.54 μM, respectively ( p = 0.12). There was no significant difference in hemodynamic response (mean accΔHbO 2 ) between the two groups during the digit span backward and VFT. In conclusion, reduced hemodynamics in the frontal cortex of the depressive-symptom group has been observed. The frontal fNIRS signal and the Stroop task may be used to measure depressive symptoms sensitively in the elderly.
This study aimed to investigate differences in prefrontal cortex activation between older adults with and without depressive symptoms during cognitive tasks using functional near-infrared spectroscopy (fNIRS). We examined 204 older participants without psychiatric or neurological disorders who completed the Geriatric Depression Scale, digit span, Verbal Fluency Test, and Stroop test. At the same time, prefrontal cortex activation was recorded using fNIRS. During the Stroop test, significantly reduced hemodynamics were observed in the depressive-symptom group. The mean accΔHbO of all channel averages was 0.14 μM in the control group and -0.75 μM in the depressive-symptom group ( = 0.03). The right hemisphere average was 0.13 μM and -0.96 μM, respectively ( = 0.02), and the left hemisphere average was 0.14 μM and -0.54 μM, respectively ( = 0.12). There was no significant difference in hemodynamic response (mean accΔHbO ) between the two groups during the digit span backward and VFT. In conclusion, reduced hemodynamics in the frontal cortex of the depressive-symptom group has been observed. The frontal fNIRS signal and the Stroop task may be used to measure depressive symptoms sensitively in the elderly.
Audience Academic
Author Yang, Young-Soon
Kang, Min-Ju
Choi, Jong-Kwan
Cho, Su-Yeon
AuthorAffiliation 3 OBELAB Inc., Seoul 06211, Republic of Korea
1 Department of Neurology, Veterans Health Service Medical Center, Seoul 05368, Republic of Korea
4 Department of Neurology, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan 31151, Republic of Korea
2 Veterans Medical Research Institute, Seoul 05368, Republic of Korea
AuthorAffiliation_xml – name: 2 Veterans Medical Research Institute, Seoul 05368, Republic of Korea
– name: 4 Department of Neurology, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan 31151, Republic of Korea
– name: 1 Department of Neurology, Veterans Health Service Medical Center, Seoul 05368, Republic of Korea
– name: 3 OBELAB Inc., Seoul 06211, Republic of Korea
Author_xml – sequence: 1
  givenname: Min-Ju
  surname: Kang
  fullname: Kang, Min-Ju
  organization: Veterans Medical Research Institute, Seoul 05368, Republic of Korea
– sequence: 2
  givenname: Su-Yeon
  surname: Cho
  fullname: Cho, Su-Yeon
  organization: Veterans Medical Research Institute, Seoul 05368, Republic of Korea
– sequence: 3
  givenname: Jong-Kwan
  orcidid: 0000-0003-2159-9246
  surname: Choi
  fullname: Choi, Jong-Kwan
  organization: OBELAB Inc., Seoul 06211, Republic of Korea
– sequence: 4
  givenname: Young-Soon
  orcidid: 0000-0002-2448-2599
  surname: Yang
  fullname: Yang, Young-Soon
  organization: Department of Neurology, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan 31151, Republic of Korea
BackLink https://www.ncbi.nlm.nih.gov/pubmed/37508986$$D View this record in MEDLINE/PubMed
BookMark eNptUk1vEzEUXKEiWkrvnNBKXLikPH_F3hOKQoFIFSAazpbjj63Drh3s3aL8e5ymRE2FfbD1PDPP8zQvq5MQg62q1wguCWng_SopH7L2iABHwOiz6gwDn04Ixezk0f20ush5DWUJAMLgRXVKOAPRiOlZtXRfFz9u6lnONufehqE2Y_KhreexDX7wd7Zeqvwr1z7UV52xqdvW39XgCzLXf_xwW3-0m1S4O-TNtt8Msc-vqudOddlePJzn1c9PV8v5l8n1t8-L-ex6ohkTwwQj3RjqnFiVrzYMG4QdEgqY48ZhB5gywUEpPaXCWEb5lGvEAWtELBHGkfNqsdc1Ua3lJvlepa2Mysv7QkytVGnwurNyRYwhhIIgGmhDRGNWiBmmtEKsjI8WrQ97rc246q3RxWBS3ZHo8Uvwt7KNdxIB4Rw3uCi8e1BI8fdo8yB7n7XtOhVsHLPEglJoOLpv9vYJdB3HFMqsdigCBKMie0C1qjjwwcXSWO9E5Ywz0RQjrCmoy_-gyja297pExvlSPyLAnqBTzDlZdzCJQO6SJZ8mq1DePB7OgfAvR-Qv9ArKjA
CitedBy_id crossref_primary_10_1016_j_pscychresns_2024_111810
crossref_primary_10_1016_j_jad_2024_06_013
Cites_doi 10.1080/01688638208401139
10.1007/s00429-008-0189-x
10.1046/j.1525-1497.1999.00326.x
10.1002/hbm.10026
10.3389/fnhum.2016.00529
10.1016/S0006-3223(02)01338-0
10.1097/00019442-200205000-00004
10.1088/0031-9155/33/12/008
10.1109/JSSC.2015.2504412
10.1016/j.jpsychores.2004.01.004
10.1016/j.neuroimage.2012.04.005
10.1016/j.neuropsychologia.2004.04.023
10.1159/000068871
10.1177/089198879100400310
10.31083/j.jin2104113
10.1038/s41598-018-30487-6
10.1016/j.jad.2006.11.004
10.1203/00006450-199605000-00025
10.1016/j.ebiom.2019.11.047
10.1016/S0006-3223(01)01216-1
10.1111/nyas.13948
10.1002/gps.4715
10.2147/DMSO.S179071
10.1097/JGP.0b013e3181cb87d6
10.1038/s41598-020-66784-2
10.1159/000323446
10.1016/j.psc.2013.08.002
10.1097/JGP.0b013e3181e751c4
10.3389/fpsyt.2020.00378
10.1126/science.288.5472.1835
10.1001/jama.291.9.1081
10.1038/sj.npp.1300551
10.1088/0967-3334/29/7/001
10.1155/2019/7845104
10.1111/pcn.12209
10.1016/j.brainresrev.2008.06.003
10.3390/ijerph16020255
10.1177/1073191111428764
ContentType Journal Article
Copyright COPYRIGHT 2023 MDPI AG
2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
2023 by the authors. 2023
Copyright_xml – notice: COPYRIGHT 2023 MDPI AG
– notice: 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
– notice: 2023 by the authors. 2023
DBID NPM
AAYXX
CITATION
3V.
7TK
7XB
8FE
8FH
8FK
8G5
ABUWG
AFKRA
AZQEC
BBNVY
BENPR
BHPHI
CCPQU
DWQXO
GNUQQ
GUQSH
HCIFZ
LK8
M2O
M7P
MBDVC
PIMPY
PQEST
PQQKQ
PQUKI
PRINS
Q9U
7X8
5PM
DOA
DOI 10.3390/brainsci13071054
DatabaseName PubMed
CrossRef
ProQuest Central (Corporate)
Neurosciences Abstracts
ProQuest Central (purchase pre-March 2016)
ProQuest SciTech Collection
ProQuest Natural Science Collection
ProQuest Central (Alumni) (purchase pre-March 2016)
Research Library (Alumni Edition)
ProQuest Central (Alumni)
ProQuest Central
ProQuest Central Essentials
Biological Science Collection
ProQuest Central
Natural Science Collection
ProQuest One Community College
ProQuest Central Korea
ProQuest Central Student
Research Library Prep
SciTech Premium Collection (Proquest) (PQ_SDU_P3)
ProQuest Biological Science Collection
Research Library
Biological Science Database
Research Library (Corporate)
Publicly Available Content Database
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
ProQuest Central Basic
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle PubMed
CrossRef
Publicly Available Content Database
Research Library Prep
ProQuest Central Student
ProQuest Biological Science Collection
ProQuest Central Basic
ProQuest Central Essentials
ProQuest One Academic Eastern Edition
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
Research Library (Alumni Edition)
ProQuest Natural Science Collection
Biological Science Database
ProQuest SciTech Collection
Neurosciences Abstracts
ProQuest Central China
ProQuest Central
ProQuest One Academic UKI Edition
Natural Science Collection
ProQuest Central Korea
Biological Science Collection
ProQuest Research Library
ProQuest One Academic
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList CrossRef


Publicly Available Content Database

PubMed
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Anatomy & Physiology
EISSN 2076-3425
ExternalDocumentID oai_doaj_org_article_b3dd334083c049389db15d5aca150714
A758904959
10_3390_brainsci13071054
37508986
Genre Journal Article
GeographicLocations South Korea
GeographicLocations_xml – name: South Korea
GrantInformation_xml – fundername: VHS Medical Center research grant
  grantid: VHSMC20037
– fundername: VHS Medical Center research
  grantid: VHSMC20037
– fundername: Ministry of Health & Welfare
  grantid: HI22C1234
– fundername: Korea Health Industry Development Institute (KHIDI)
GroupedDBID 3V.
53G
5VS
8FE
8FH
8G5
AADQD
AAFWJ
ABDBF
ABUWG
ADBBV
AFKRA
AFZYC
ALMA_UNASSIGNED_HOLDINGS
AOIJS
AZQEC
BBNVY
BCNDV
BENPR
BHPHI
BPHCQ
CCPQU
DWQXO
EBD
ESX
GNUQQ
GROUPED_DOAJ
GUQSH
HCIFZ
HYE
IAO
IHR
ITC
KQ8
LK8
M2O
M48
M7P
MODMG
M~E
NPM
OK1
PGMZT
PIMPY
PQQKQ
PROAC
RPM
AAYXX
AFPKN
CITATION
7TK
7XB
8FK
MBDVC
PQEST
PQUKI
PRINS
Q9U
7X8
5PM
ID FETCH-LOGICAL-c558t-21c9d4ff8b076952d12f18a05f7df2f0245870aac648de54767c1702c13e38df3
IEDL.DBID RPM
ISSN 2076-3425
IngestDate Tue Oct 22 15:11:57 EDT 2024
Tue Sep 17 21:31:05 EDT 2024
Fri Aug 16 00:28:27 EDT 2024
Thu Oct 10 18:20:30 EDT 2024
Thu Feb 22 23:44:08 EST 2024
Fri Feb 02 04:41:57 EST 2024
Fri Aug 23 01:58:35 EDT 2024
Wed Oct 16 00:38:25 EDT 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 7
Keywords fNIRS
depression
geriatric depression scale
functional near-infrared spectroscopy
Language English
License Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c558t-21c9d4ff8b076952d12f18a05f7df2f0245870aac648de54767c1702c13e38df3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ORCID 0000-0002-2448-2599
0000-0003-2159-9246
OpenAccessLink https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10377292/
PMID 37508986
PQID 2843032110
PQPubID 2032423
ParticipantIDs doaj_primary_oai_doaj_org_article_b3dd334083c049389db15d5aca150714
pubmedcentral_primary_oai_pubmedcentral_nih_gov_10377292
proquest_miscellaneous_2844097114
proquest_journals_2843032110
gale_infotracmisc_A758904959
gale_infotracacademiconefile_A758904959
crossref_primary_10_3390_brainsci13071054
pubmed_primary_37508986
PublicationCentury 2000
PublicationDate 2023-07-01
PublicationDateYYYYMMDD 2023-07-01
PublicationDate_xml – month: 07
  year: 2023
  text: 2023-07-01
  day: 01
PublicationDecade 2020
PublicationPlace Switzerland
PublicationPlace_xml – name: Switzerland
– name: Basel
PublicationTitle Brain sciences
PublicationTitleAlternate Brain Sci
PublicationYear 2023
Publisher MDPI AG
MDPI
Publisher_xml – name: MDPI AG
– name: MDPI
References Morimoto (ref_27) 2013; 36
Bendall (ref_12) 2016; 10
Ng (ref_3) 2018; 8
Lee (ref_23) 2000; 19
Vu (ref_5) 2018; 11
Husain (ref_10) 2020; 51
Pinti (ref_14) 2020; 1464
Gerton (ref_35) 2004; 42
Diener (ref_34) 2012; 61
Potter (ref_28) 2004; 29
Kimbrell (ref_32) 2002; 51
Oxman (ref_8) 2002; 10
Ho (ref_33) 2020; 11
Laudisio (ref_20) 2018; 33
Unutzer (ref_2) 2002; 52
Burke (ref_18) 1991; 4
Watson (ref_19) 2003; 52
Delpy (ref_25) 1988; 33
Schroeder (ref_22) 2012; 19
Melcher (ref_37) 2008; 59
Lee (ref_42) 2007; 101
MacDonald (ref_38) 2000; 288
Simeonova (ref_40) 2022; 21
Lyness (ref_1) 1999; 14
Morimoto (ref_29) 2011; 19
Duncan (ref_26) 1996; 39
Liu (ref_39) 2008; 29
Drevets (ref_30) 2008; 213
Zhang (ref_15) 2015; 69
Colier (ref_13) 2002; 16
Pendleton (ref_24) 1982; 4
Bruce (ref_9) 2004; 291
Choi (ref_21) 2016; 51
Yoon (ref_41) 2019; 2019
Grabovich (ref_6) 2010; 18
Okada (ref_31) 2003; 47
Remick (ref_7) 2002; 167
ref_4
Kaneko (ref_36) 2011; 63
Husain (ref_11) 2020; 10
Kurlowicz (ref_16) 2000; 25
Bae (ref_17) 2004; 57
References_xml – volume: 25
  start-page: 18
  year: 2000
  ident: ref_16
  article-title: The geriatric depression scale (GDS)
  publication-title: Insight
  contributor:
    fullname: Kurlowicz
– volume: 4
  start-page: 307
  year: 1982
  ident: ref_24
  article-title: Diagnostic utility of the Thurstone Word Fluency Test in neuropsychological evaluations
  publication-title: J. Clin. Neuropsychol.
  doi: 10.1080/01688638208401139
  contributor:
    fullname: Pendleton
– volume: 52
  start-page: 956
  year: 2003
  ident: ref_19
  article-title: Screening accuracy for late-life depression in primary care: A systematic review
  publication-title: J. Fam. Pract.
  contributor:
    fullname: Watson
– volume: 213
  start-page: 93
  year: 2008
  ident: ref_30
  article-title: Brain structural and functional abnormalities in mood disorders: Implications for neurocircuitry models of depression
  publication-title: Brain Struct. Funct.
  doi: 10.1007/s00429-008-0189-x
  contributor:
    fullname: Drevets
– volume: 167
  start-page: 1253
  year: 2002
  ident: ref_7
  article-title: Diagnosis and management of depression in primary care: A clinical update and review
  publication-title: Cmaj
  contributor:
    fullname: Remick
– volume: 14
  start-page: 249
  year: 1999
  ident: ref_1
  article-title: Psychiatric disorders in older primary care patients
  publication-title: J. Gen. Intern. Med.
  doi: 10.1046/j.1525-1497.1999.00326.x
  contributor:
    fullname: Lyness
– volume: 16
  start-page: 14
  year: 2002
  ident: ref_13
  article-title: Simultaneous measurements of cerebral oxygenation changes during brain activation by near-infrared spectroscopy and functional magnetic resonance imaging in healthy young and elderly subjects
  publication-title: Hum. Brain Mapp.
  doi: 10.1002/hbm.10026
  contributor:
    fullname: Colier
– volume: 10
  start-page: 529
  year: 2016
  ident: ref_12
  article-title: A Brief Review of Research Using Near-Infrared Spectroscopy to Measure Activation of the Prefrontal Cortex during Emotional Processing: The Importance of Experimental Design
  publication-title: Front. Hum. Neurosci.
  doi: 10.3389/fnhum.2016.00529
  contributor:
    fullname: Bendall
– volume: 52
  start-page: 285
  year: 2002
  ident: ref_2
  article-title: Diagnosis and treatment of older adults with depression in primary care
  publication-title: Biol. Psychiatry
  doi: 10.1016/S0006-3223(02)01338-0
  contributor:
    fullname: Unutzer
– volume: 10
  start-page: 256
  year: 2002
  ident: ref_8
  article-title: Treatment of minor depression
  publication-title: Am. J. Geriatr. Psychiatry
  doi: 10.1097/00019442-200205000-00004
  contributor:
    fullname: Oxman
– volume: 33
  start-page: 1433
  year: 1988
  ident: ref_25
  article-title: Estimation of optical pathlength through tissue from direct time of flight measurement
  publication-title: Phys. Med. Biol.
  doi: 10.1088/0031-9155/33/12/008
  contributor:
    fullname: Delpy
– volume: 51
  start-page: 484
  year: 2016
  ident: ref_21
  article-title: Time-Divided Spread-Spectrum Code-Based 400 fW-Detectable Multichannel fNIRS IC for Portable Functional Brain Imaging
  publication-title: IEEE J. Solid-State Circuits
  doi: 10.1109/JSSC.2015.2504412
  contributor:
    fullname: Choi
– volume: 57
  start-page: 297
  year: 2004
  ident: ref_17
  article-title: Development of the Korean version of the Geriatric Depression Scale and its short form among elderly psychiatric patients
  publication-title: J. Psychosom. Res.
  doi: 10.1016/j.jpsychores.2004.01.004
  contributor:
    fullname: Bae
– volume: 61
  start-page: 677
  year: 2012
  ident: ref_34
  article-title: A meta-analysis of neurofunctional imaging studies of emotion and cognition in major depression
  publication-title: Neuroimage
  doi: 10.1016/j.neuroimage.2012.04.005
  contributor:
    fullname: Diener
– volume: 42
  start-page: 1781
  year: 2004
  ident: ref_35
  article-title: Shared and distinct neurophysiological components of the digits forward and backward tasks as revealed by functional neuroimaging
  publication-title: Neuropsychologia
  doi: 10.1016/j.neuropsychologia.2004.04.023
  contributor:
    fullname: Gerton
– volume: 47
  start-page: 21
  year: 2003
  ident: ref_31
  article-title: Attenuated left prefrontal activation during a verbal fluency task in patients with depression
  publication-title: Neuropsychobiology
  doi: 10.1159/000068871
  contributor:
    fullname: Okada
– volume: 4
  start-page: 173
  year: 1991
  ident: ref_18
  article-title: The short form of the Geriatric Depression Scale: A comparison with the 30-item form
  publication-title: J. Geriatr. Psychiatry Neurol
  doi: 10.1177/089198879100400310
  contributor:
    fullname: Burke
– volume: 21
  start-page: 113
  year: 2022
  ident: ref_40
  article-title: Functional MRI Correlates of Stroop N-Back Test Underpin the Diagnosis of Major Depression
  publication-title: J. Integr. Neurosci.
  doi: 10.31083/j.jin2104113
  contributor:
    fullname: Simeonova
– volume: 19
  start-page: 807
  year: 2000
  ident: ref_23
  article-title: Efficiencies of stroop interference indexes in healthy older adults and dementia patients
  publication-title: Korean J. Clin. Psychol.
  contributor:
    fullname: Lee
– volume: 8
  start-page: 12050
  year: 2018
  ident: ref_3
  article-title: IL-1β, IL-6, TNF-α and CRP in Elderly Patients with Depression or Alzheimer’s disease: Systematic Review and Meta-Analysis
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-018-30487-6
  contributor:
    fullname: Ng
– volume: 101
  start-page: 123
  year: 2007
  ident: ref_42
  article-title: Long-term outcome of depressive pseudodementia in the elderly
  publication-title: J. Affect Disord.
  doi: 10.1016/j.jad.2006.11.004
  contributor:
    fullname: Lee
– volume: 39
  start-page: 889
  year: 1996
  ident: ref_26
  article-title: Measurement of cranial optical path length as a function of age using phase resolved near infrared spectroscopy
  publication-title: Pediatr. Res.
  doi: 10.1203/00006450-199605000-00025
  contributor:
    fullname: Duncan
– volume: 51
  start-page: 102586
  year: 2020
  ident: ref_10
  article-title: Cortical haemodynamic response measured by functional near infrared spectroscopy during a verbal fluency task in patients with major depression and borderline personality disorder
  publication-title: eBioMedicine
  doi: 10.1016/j.ebiom.2019.11.047
  contributor:
    fullname: Husain
– volume: 51
  start-page: 237
  year: 2002
  ident: ref_32
  article-title: Regional cerebral glucose utilization in patients with a range of severities of unipolar depression
  publication-title: Biol. Psychiatry
  doi: 10.1016/S0006-3223(01)01216-1
  contributor:
    fullname: Kimbrell
– volume: 1464
  start-page: 5
  year: 2020
  ident: ref_14
  article-title: The present and future use of functional near-infrared spectroscopy (fNIRS) for cognitive neuroscience
  publication-title: Ann. N. Y. Acad. Sci.
  doi: 10.1111/nyas.13948
  contributor:
    fullname: Pinti
– volume: 33
  start-page: e58
  year: 2018
  ident: ref_20
  article-title: Definition of a Geriatric Depression Scale cutoff based upon quality of life: A population-based study
  publication-title: Int. J. Geriatr. Psychiatry
  doi: 10.1002/gps.4715
  contributor:
    fullname: Laudisio
– volume: 11
  start-page: 659
  year: 2018
  ident: ref_5
  article-title: Depressive symptoms among elderly diabetic patients in Vietnam
  publication-title: Diabetes Metab. Syndr. Obes.
  doi: 10.2147/DMSO.S179071
  contributor:
    fullname: Vu
– volume: 18
  start-page: 227
  year: 2010
  ident: ref_6
  article-title: Outcomes of subsyndromal depression in older primary care patients
  publication-title: Am. J. Geriatr. Psychiatry
  doi: 10.1097/JGP.0b013e3181cb87d6
  contributor:
    fullname: Grabovich
– volume: 10
  start-page: 9740
  year: 2020
  ident: ref_11
  article-title: Validating a functional near-infrared spectroscopy diagnostic paradigm for Major Depressive Disorder
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-020-66784-2
  contributor:
    fullname: Husain
– volume: 63
  start-page: 59
  year: 2011
  ident: ref_36
  article-title: Hemodynamic changes in the prefrontal cortex during digit span task: A near-infrared spectroscopy study
  publication-title: Neuropsychobiology
  doi: 10.1159/000323446
  contributor:
    fullname: Kaneko
– volume: 36
  start-page: 517
  year: 2013
  ident: ref_27
  article-title: Cognitive deficits in geriatric depression: Clinical correlates and implications for current and future treatment
  publication-title: Psychiatr. Clin. N. Am.
  doi: 10.1016/j.psc.2013.08.002
  contributor:
    fullname: Morimoto
– volume: 19
  start-page: 115
  year: 2011
  ident: ref_29
  article-title: Executive function and short-term remission of geriatric depression: The role of semantic strategy
  publication-title: Am. J. Geriatr. Psychiatry
  doi: 10.1097/JGP.0b013e3181e751c4
  contributor:
    fullname: Morimoto
– volume: 11
  start-page: 378
  year: 2020
  ident: ref_33
  article-title: Diagnostic and Predictive Applications of Functional Near-Infrared Spectroscopy for Major Depressive Disorder: A Systematic Review
  publication-title: Front. Psychiatry
  doi: 10.3389/fpsyt.2020.00378
  contributor:
    fullname: Ho
– volume: 288
  start-page: 1835
  year: 2000
  ident: ref_38
  article-title: Dissociating the Role of the Dorsolateral Prefrontal and Anterior Cingulate Cortex in Cognitive Control
  publication-title: Science
  doi: 10.1126/science.288.5472.1835
  contributor:
    fullname: MacDonald
– volume: 291
  start-page: 1081
  year: 2004
  ident: ref_9
  article-title: Reducing suicidal ideation and depressive symptoms in depressed older primary care patients: A randomized controlled trial
  publication-title: JAMA
  doi: 10.1001/jama.291.9.1081
  contributor:
    fullname: Bruce
– volume: 29
  start-page: 2266
  year: 2004
  ident: ref_28
  article-title: Prefrontal neuropsychological predictors of treatment remission in late-life depression
  publication-title: Neuropsychopharmacology
  doi: 10.1038/sj.npp.1300551
  contributor:
    fullname: Potter
– volume: 29
  start-page: 703
  year: 2008
  ident: ref_39
  article-title: Cognitive control explored by linear modelling behaviour and fMRI data during Stroop tasks
  publication-title: Physiol. Meas.
  doi: 10.1088/0967-3334/29/7/001
  contributor:
    fullname: Liu
– volume: 2019
  start-page: 7845104
  year: 2019
  ident: ref_41
  article-title: Neural Compensatory Response During Complex Cognitive Function Tasks in Mild Cognitive Impairment: A Near-Infrared Spectroscopy Study
  publication-title: Neural Plast.
  doi: 10.1155/2019/7845104
  contributor:
    fullname: Yoon
– volume: 69
  start-page: 22
  year: 2015
  ident: ref_15
  article-title: Near-infrared spectroscopy for examination of prefrontal activation during cognitive tasks in patients with major depressive disorder: A meta-analysis of observational studies
  publication-title: Psychiatry Clin. Neurosci.
  doi: 10.1111/pcn.12209
  contributor:
    fullname: Zhang
– volume: 59
  start-page: 96
  year: 2008
  ident: ref_37
  article-title: Functional brain abnormalities in psychiatric disorders: Neural mechanisms to detect and resolve cognitive conflict and interference
  publication-title: Brain Res. Rev.
  doi: 10.1016/j.brainresrev.2008.06.003
  contributor:
    fullname: Melcher
– ident: ref_4
  doi: 10.3390/ijerph16020255
– volume: 19
  start-page: 21
  year: 2012
  ident: ref_22
  article-title: Reliable Digit Span: A systematic review and cross-validation study
  publication-title: Assessment
  doi: 10.1177/1073191111428764
  contributor:
    fullname: Schroeder
SSID ssj0000800350
Score 2.2993667
Snippet This study aimed to investigate differences in prefrontal cortex activation between older adults with and without depressive symptoms during cognitive tasks...
SourceID doaj
pubmedcentral
proquest
gale
crossref
pubmed
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
StartPage 1054
SubjectTerms Aged patients
Blood & organ donations
Cognitive ability
Communication
Cortex (frontal)
depression
Depression, Mental
fNIRS
functional near-infrared spectroscopy
geriatric depression scale
Geriatrics
Hemispheric laterality
Hemodynamics
Hemoglobin
Infrared spectroscopy
Mental depression
Mental disorders
Neurological diseases
Older people
Prefrontal cortex
Primary care
Psychological aspects
Questionnaires
Spectrum analysis
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELZQT1wQUB6BFrlSBeIQNbbjxD4upVWLRIXoVurNil-iQNOKbA_77ztjZ1cbeuDCNXYUe8bj-cYZf0PIvtSVY66LZWOdLmvnRalCy0urnOUBNkObUv6_njUnF_WXS3m5UeoLc8IyPXAW3IEV3gtRA1JwAGbBvXrLpJed6xKUyUygTG4EUz9HHCRklf9LCojrDyxWXACvAns2OFVZT_xQout_uClveKVpxuSGCzp-Sp6M2JHO8pifkUehf062Zz3EzddL-p6mbM50TL5N5vHs9Ps5na2JN2m-kEgPV_lCdN4NvwZ61dMjrNT9e0m_ZY7VgeLhLP085shCz_Pl9S18Y3hBLo6P5ocn5VhBoXRSqkXJmdO-jlHZqm205J7xyFRXydj6yCP-dgV77TrX1MoHWbdN61hbcYdno8pH8ZJs9Td9eE1o63RkEdCSbzSEdIBbsJaVaIKLIUJMVZCPK3ma20yUYSDAQNmbv2VfkE8o8HU_pLhOD0DxZlS8-ZfiC_IB1WXQEEEnrhvvE8BwkdLKzCAS0vCm1AXZmfQEA3LT5pXCzWjAgwGvDc4do-OC7K2b8U1MSuvDzV3qg2xhDMfyKq-P9ZQEIDGlVVMQNVk5kzlPW_qrH4neG29uQsjD3_wPKb0ljznAspxgvEO2Fn_uwi7AqIV9lyzmHkZ-Gk8
  priority: 102
  providerName: Directory of Open Access Journals
– databaseName: ProQuest Central
  dbid: BENPR
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Nb9QwELWgvXBBhfIRKMhICMQhauzEiX1C27JVQWJVtVupNyu241JBs9tme9h_z4zjDQ1IXNdO1rE9M--NxzOEvBcqs8zWPi2NVWlhXZ7KpuKpkdbwBpShCSH_32fl8Xnx7UJcRIdbF8MqNzoxKGq3sOgj3wc1CtoW6crn5U2KVaPwdDWW0HhItjkr8Jh2-2A6OzkdvCyIh3KR9eeTOfD7fYOVF8C6gO4G4yqKkT0Kafv_Vc73rNM4cvKeKTraIY8jhqSTftGfkAdN-5TsTlrgz9dr-oGGqM7gLt8lcz_7enpGJ0MCTtpfTKSHm7ghOq-7nx29aukUK3b_WtOTPtdqR9FJS7_EWFnoeba-XsJ_dM_I-dF0fnicxkoKqRVCrlLOrHKF99JkVakEd4x7JutM-Mp57vH4FeS2rm1ZSNeIoiory6qMW_SRSufz52SrXbTNS0IrqzzzgJpcqYDaAX7BmlZ52VjfeOBWCfm0mU-97BNmaCAaOPf677lPyAFO-NAPU12HHxa3lzpKjja5c3leAFS0wGYAXznDhBO1rQOWhZd8xOXSKJCwJraO9wpguJjaSk-AESl4UqiE7I16giDZcfNmwXUU5E7_2XYJeTc045MYnNY2i7vQB7OGMRzLi35_DJ-UAyKTSpYJkaOdM_rmcUt79SOk-cYbnEB9-Kv_j-s1ecQBePUhxHtka3V717wBoLQyb6M0_AYLqhPV
  priority: 102
  providerName: ProQuest
– databaseName: Scholars Portal Journals: Open Access
  dbid: M48
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1Lb9QwELagXLigQnmkFGQkBOIQ2PiR2AeEltKqILVCdFfqzYpfUGizZbOV2H_PjJNdGuiFa-w8PJ7xfJ8zniHkudQjV7g65qV1OhfO81yFiuVWOcsCLIY2hfwfHpUHU_HpRJ78OR7dC7C9ltphPanp_Oz1r5_Ld2Dwb5FxAmV_Y7GYAjgMWI7BX0pxk9xiggvU98Me7H_vsRFPJVsZkPecg7Z2_y2vfcjAT6V0_v8u2le81jCi8oqL2t8kd3psScedMtwlN0Jzj2yNG-DV50v6gqZoz7SNvkUm8ejjl2M6XifmpN2BRbq7iieik7r90dLThu5hJe-zJf3c5WBtKW7e0g99DC30PF6eX8A72vtkur832T3I-woLuZNSLXJWOO1FjMqCRLRkvmCxUPVIxspHFvG3LNhzXbtSKB-kqMrKFdWIOdw7VT7yB2SjmTXhEaGV07GIgKZ8qYHyAa7BWle8DC6GCJwrI69W8jQXXSINAwQEZW_-ln1G3qPA1_0wBXa6MJt_Nb1FGcu951wAhHTAcgB3eVtIL2tXJ4wLD3mJ02VQdWBOXN2fN4DPxZRXZgxMScOdUmdkZ9ATDMwNm1cTblb6acCrg_NH9pyRZ-tmvBOD1powu0x9MJtYgd_ysNOP9ZA4IDWlVZkRNdCcwZiHLc3pt5T-G092AiVi2_8h0cfkNgN01sUZ75CNxfwyPAE0tbBPk5H8BrlaHQI
  priority: 102
  providerName: Scholars Portal
Title fNIRS Assessment during Cognitive Tasks in Elderly Patients with Depressive Symptoms
URI https://www.ncbi.nlm.nih.gov/pubmed/37508986
https://www.proquest.com/docview/2843032110
https://search.proquest.com/docview/2844097114
https://pubmed.ncbi.nlm.nih.gov/PMC10377292
https://doaj.org/article/b3dd334083c049389db15d5aca150714
Volume 13
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Nb9swDCXa7rLL0K378NoFGjBs2MFNbFm2fEyzFN2ABEGbAr0ZlmR12RonqNND_v1I2Q7i7bZLDpbkyCYlPsqPJMAnkQ50oHPrx0qnfqQN92WRhL6SWoUFbobKUf4n0_jqNvpxJ-4OIG5jYRxpX6vFefmwPC8XPx23cr3U_ZYn1p9NRhTbhqAw7B_CYcL5no_-q8FAXAzqb5Icffq-omoLaFFwv0aDKqgWD0dLKVOKoN4zRy5r_797855x6hIn9yzR5TG8aCAkG9ZTfQkHRfkKToYlus_LLfvMHKnTnZafwNxOv1_fsOEu_yar4xLZqKUNsXle_a7YomRjKtj9sGWzOtVqxeiMln1rqLLY82a7XON_VK_h9nI8H135TSEFXwshN34Y6NRE1ko1SOJUhCYIbSDzgbCJsaGlr6-4bPNcx5E0hYiSONFBMgg1HZFKY_kbOCpXZfEOWKJTG1gETSZO0bND-EIlrXhcaFtYdK08-Nq-z2xd58vI0M8gMWR_i8GDC3rhu36U6dpdWD3eZ428M8WN4TxCpKjRmUF4ZVQgjMh17qAs3uQLiSuj9Ygy0XkTVoDTpcxW2RAdohRHitSDs05PXEe629wKPGvWcZWh8UYbT06yBx93zTSSuGllsXpyfShpWEBzeVvrx-6RWjXzQHY0p_PM3RZUepflu1Xy9_8_9BSeh4jJanbxGRxtHp-KD4ihNqoHzy7G09l1z51B4O8kkj23jP4AqEUfZQ
link.rule.ids 230,315,733,786,790,870,891,2115,2236,21416,24346,27955,27956,33777,33778,43838,53825,53827,74657
linkProvider National Library of Medicine
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwEB7B9gAXBJRHoICREIhD1LycOCe0LVttoV1V7VbqzUr8gAqaXZrtYf89M443NCBxXTtZx_bMfN94PAPwjpeRilVlw7xWZZgpnYbCFElYC1UnBpVh7UL-j2f59Dz7csEvvMOt9WGVG53oFLVeKPKR76IaRW1LdOXT8ldIVaPodNWX0LgLW5RyU4xga28yOzntvSyEh1IedeeTKfL73ZoqL6B1Qd2NxpVnA3vk0vb_q5xvWadh5OQtU3TwEB54DMnG3aI_gjumeQzb4wb589WavWcuqtO5y7dhbmeHp2ds3CfgZN3FRLa_iRti86r90bLLhk2oYvfPNTvpcq22jJy07LOPlcWeZ-urJf5H-wTODybz_WnoKymEinOxCpNYlTqzVtRRkZc80XFiY1FF3BbaJpaOX1Fuq0rlmdCGZ0VeqLiIEkU-UqFt-hRGzaIxz4EVqrSxRdSk8xKpHeIXqmmV5kZZY5FbBfBxM59y2SXMkEg0aO7l33MfwB5NeN-PUl27HxbX36SXHFmnWqdphlBRIZtBfKXrmGteqcphWXzJB1ouSQKJa6Iqf68Ah0upreQYGVGJT_IygJ1BTxQkNWzeLLj0gtzKP9sugLd9Mz1JwWmNWdy4PpQ1LKaxPOv2R_9JKSIyUYo8ADHYOYNvHrY0l99dmm-6wYnUJ3nx_3G9gXvT-fGRPDqcfX0J9xMEYV048Q6MVtc35hWCplX92kvGbz7HFss
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3db9MwELdgkxAvCBiw7AOMhEA8RE3i2HGepm5rtfFRVVsn7c1K_AETW9ot3UP_e-4SNywg8Vo7qWP77n6_8_mOkA88j3SsCxeKUudhqg0Lpc2SsJS6TCwow7IJ-f8-EScX6ZdLfunjn2ofVrnWiY2iNnONPvIBqFHQtkhXBs6HRUyPxweL2xArSOFJqy-n8ZhsZqngQMQ2D0eT6VnncUFsxHjUnlUy4PqDEqswgKUBPQ6Glqc929Sk8P9XUT-wVP0oygdmafycPPN4kg7bDfCCPLLVS7I1rIBL36zoR9pEeDau8y0yc5PTs3M67JJx0vaSIj1axxDRWVH_qulVRUdYvft6Radt3tWaosOWHvu4Weh5vrpZwH_Ur8jFeDQ7Ogl9VYVQcy6XYRLr3KTOyTLKRM4TEyculkXEXWZc4vAoFmS4KLRIpbE8zUSm4yxKNPpLpXHsNdmo5pXdJjTTuYsdICgjcqB5gGWwvhUTVjvrgGcF5PN6PtWiTZ6hgHTg3Ku_5z4ghzjhXT9Me938ML_7obwUqZIZw1gKsFEDswGsZcqYG17oosG18JJPuFwKhRPWRBf-jgEMF9NcqSGwoxye5HlA9no9Qah0v3m94MoLda3-bMGAvO-a8UkMVKvs_L7pgxnEYhzLm3Z_dJ_EAJ3JXIqAyN7O6X1zv6W6-tmk_MbbnECDkp3_j-sdeQJCob6dTr7ukqcJ4LE2sniPbCzv7u0-4Kdl-dYLxm9RqBr_
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=fNIRS+Assessment+during+Cognitive+Tasks+in+Elderly+Patients+with+Depressive+Symptoms&rft.jtitle=Brain+sciences&rft.au=Kang%2C+Min-Ju&rft.au=Cho%2C+Su-Yeon&rft.au=Choi%2C+Jong-Kwan&rft.au=Yang%2C+Young-Soon&rft.date=2023-07-01&rft.issn=2076-3425&rft.eissn=2076-3425&rft.volume=13&rft.issue=7&rft.spage=1054&rft_id=info:doi/10.3390%2Fbrainsci13071054&rft.externalDBID=n%2Fa&rft.externalDocID=10_3390_brainsci13071054
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2076-3425&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2076-3425&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2076-3425&client=summon