Activation of Epidermal Toll-Like Receptor 2 Enhances Tight Junction Function: Implications for Atopic Dermatitis and Skin Barrier Repair - Kuo, I-Hsin; Carpenter-Mendini, Amanda; Yoshida, Takeshi; McGirt, Laura Y.; Ivanov, Andrei I.; Barnes, Kathleen C.; Gallo, Richard L.; Borkowski, Andrew W.; Yamasaki, Kenshi; Leung, Donald Y.; Georas, Steve N.; De Benedetto, Anna; et al. (Journal of investigative dermatology, 2013)
Keywords: Animals; Antibodies, Neutralizing - pharmacology; Atopic dermatitis; Bacterial Proteins - pharmacology; Dermatitis, Atopic - immunology; Dermatitis, Atopic - metabolism; Dermatitis, Atopic - pathology; Epidermis; Epidermis - immunology; Epidermis - metabolism; Epidermis - pathology; Female; Foreskin - cytology; Humans; Immune response; Infection; Keratinocytes; Keratinocytes - cytology; Keratinocytes - immunology; Keratinocytes - metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pattern recognition; Peptidoglycan - pharmacology; peptidoglycans; Permeability; RNA, Messenger - metabolism; Skin; Staphylococcus aureus; Tight junctions; Tight Junctions - immunology; Tight Junctions - metabolism; Tight Junctions - pathology; TLR2 protein; Toll-Like Receptor 1 - genetics; Toll-Like Receptor 1 - immunology; Toll-Like Receptor 1 - metabolism; Toll-Like Receptor 2 - agonists; Toll-Like Receptor 2 - genetics; Toll-Like Receptor 2 - metabolism; Toll-like receptors; Transcutaneous Electric Nerve Stimulation; Water loss; Wound healing; Wound Healing - physiology; Zonula occludens-1 protein