Urinary liver‐type fatty acid‐binding protein as a prognostic marker in patients with acute heart failure

• Published in: ESC Heart Failure Vol. 9; no. 1; pp. 442 - 449
• Main Authors: Sunayama, Tsutomu, Yatsu, Shoichiro, Matsue, Yuya, Dotare, Taishi, Maeda, Daichi, Ishiwata, Sayaki, Nakamura, Yutaka, Suda, Shoko, Kato, Takao, Hiki, Masaru, Kasai, Takatoshi, Minamino, Tohru
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.02.2022; John Wiley and Sons Inc; Wiley
• Subjects: Acute heart failure; Aged; Aged, 80 and over; Beta‐2 microglobulin; Biomarkers; Biomarkers - metabolism; Blood pressure; Cardiovascular disease; Chronic obstructive pulmonary disease; Coronary vessels; Datasets; Diabetes; Ejection fraction; Enzymes; Fatty Acid-Binding Proteins - metabolism; Fatty acids; Female; Heart failure; Heart Failure - metabolism; Hemoglobin; Human subjects; Humans; Hypertension; Hypoxia; Ischemia; Liver; Liver - metabolism; Male; Medical prognosis; Medical research; Middle Aged; Mortality; Original; Patients; Peptides; Prognosis; Proteins; Regression analysis; Tubular dysfunction; Urinary liver‐type fatty acid‐binding protein; Vein & artery diseases; Japan; Urinary liver-type fatty acid-binding protein; Tubular dysfunction; Prognosis; Beta-2 microglobulin; Acute heart failure

Aims Urinary liver‐type fatty acid‐binding protein (L‐FABP) is expressed in proximal tubular epithelial cells and excreted into the urine during tubular injury. We hypothesized that high urinary L‐FABP is associated with poor prognosis in patients with acute heart failure (AHF). Methods and results...