Daily Oscillation of the Excitation-Inhibition Balance in Visual Cortical Circuits

• Published in: Neuron (Cambridge, Mass.) Vol. 105; no. 4; pp. 621 - 629.e4
• Main Authors: Bridi, Michelle C.D., Zong, Fang-Jiao, Min, Xia, Luo, Nancy, Tran, Trinh, Qiu, Jiaqian, Severin, Daniel, Zhang, Xue-Ting, Wang, Guanglin, Zhu, Zheng-Jiang, He, Kai-Wen, Kirkwood, Alfredo
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 19.02.2020; Elsevier Limited
• Subjects: Animals; Circadian Rhythm - physiology; Circuits; Developmental stages; Excitatory Postsynaptic Potentials - physiology; Female; Hippocampus; Inhibitory Postsynaptic Potentials - physiology; Light; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Net - cytology; Nerve Net - physiology; Neural Inhibition - physiology; Neurological diseases; Organ Culture Techniques; Pyramidal cells; Pyramidal Cells - physiology; Sleep; Visual cortex; Visual Cortex - cytology; Visual Cortex - physiology; Visual pathways; Visual Pathways - cytology; Visual Pathways - physiology

A balance between synaptic excitation and inhibition (E/I balance) maintained within a narrow window is widely regarded to be crucial for cortical processing. In line with this idea, the E/I balance is reportedly comparable across neighboring neurons, behavioral states, and developmental stages and...