The Role of Intestinal Microbiota in Celiac Disease and Further Therapeutic Perspectives

• Published in: Life (Basel, Switzerland) Vol. 13; no. 10; p. 2039
• Main Authors: Belei, Oana, Jugănaru, Iulius, Basaca, Diana-Georgiana, Munteanu, Andrei Ioan, Mărginean, Otilia
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.10.2023; MDPI
• Subjects: Autoimmune diseases; Care and treatment; Celiac disease; Clinical medicine; Complications and side effects; Development and progression; Diabetes; Digestive system; Dysbacteriosis; Dysbiosis; Environmental factors; Epidemiology; Gastrointestinal tract; Genes; Genetic disorders; Genetic factors; Gluten; gluten-free diet; Health aspects; Health risk assessment; Industrialized nations; intestinal microbiota; Intestinal microflora; Intestine; Microbiomes; Microbiota; Microbiota (Symbiotic organisms); Modulation; Pathology; Pathophysiology; Permeability; Probiotics; Review; Serology; Signs and symptoms; Special diets; Therapeutic targets; Romania; United States > US

Celiac disease (CD) is an immune-mediated enteropathy caused by exposure to gluten and related prolamins in genetically susceptible individuals. It is a complex genetic disorder with multiple contributing genes. Linkage studies have identified several genomic regions that probably contain CD suscept...