Real-World Single-Center Comparison of the Safety and Efficacy of Entecavir, Tenofovir Disoproxil Fumarate, and Tenofovir Alafenamide in Patients with Chronic Hepatitis B

• Published in: Intervirology Vol. 65; no. 2; pp. 94 - 103
• Main Authors: Jeong, Sara, Shin, Hyun Phil, Kim, Ha Il
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 01.04.2022; Karger Publishers
• Subjects: Alanine; Antiviral Agents - adverse effects; Carcinoma, Hepatocellular; Care and treatment; chronic hepatitis b; Comparative analysis; Complications and side effects; Entecavir; Guanine - analogs & derivatives; Hepatitis B; Hepatitis B, Chronic - drug therapy; Humans; Liver; Liver cirrhosis; Liver Neoplasms; Male; Middle Aged; Research Article; Retrospective Studies; safety; Telbivudine; Tenofovir; Tenofovir - adverse effects; Tenofovir - analogs & derivatives; Treatment Outcome; South Korea; Tenofovir; Treatment outcome; Safety; Chronic hepatitis B; Entecavir
• ISSN: 0300-5526; 1423-0100; 1423-0100
• DOI: 10.1159/000519440

Introduction: Chronic hepatitis B (CHB) is a major cause of chronic liver diseases and tenofovir disoproxil fumarate (TDF), tenofovir alafenamide (TAF), and entecavir (ETV) are recommended as primary treatments. This study aimed to evaluate the efficacy and safety of ETV, TDF, and TAF in a real-worl...