Nuclear receptor interaction protein, a coactivator of androgen receptors (AR), is regulated by AR and Sp1 to feed forward and activate its own gene expression through AR protein stability - Chen, Pei-Hong; Tsao, Yeou-Ping; Wang, Chih-Chiang; Chen, Show-Li (Nucleic acids research, 2008)
Keywords: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; androgen receptors; Animals; Base Sequence; Binding Sites; Cell Line; Cell Line, Tumor; chromatin; DNA; gene expression; genes; Humans; luciferase; Male; Molecular Biology; Molecular Sequence Data; neoplasm cells; Nuclear Proteins - genetics; nucleotide sequences; precipitin tests; Promoter Regions, Genetic; Prostate cancer; prostatic neoplasms; Prostatic Neoplasms - genetics; proteasome endopeptidase complex; Receptors, Androgen - genetics; Receptors, Androgen - metabolism; RNA, Messenger - metabolism; Sp1 Transcription Factor - metabolism; transcription (genetics); Transcriptional Activation; Up-Regulation