eggNOG-mapper v2: Functional Annotation, Orthology Assignments, and Domain Prediction at the Metagenomic Scale

• Published in: Molecular biology and evolution Vol. 38; no. 12; pp. 5825 - 5829
• Main Authors: Cantalapiedra, Carlos P, Hernández-Plaza, Ana, Letunic, Ivica, Bork, Peer, Huerta-Cepas, Jaime
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 09.12.2021
• Subjects: Annotations; Databases, Genetic; Flavored milk drinks; Genes; Genomics; Metagenome; Metagenomics; Molecular Sequence Annotation; Orthology; Phylogeny; Predictions; Resources; Software; computational genomics; metagenomics; bioinformatics; functional annotation

Abstract Even though automated functional annotation of genes represents a fundamental step in most genomic and metagenomic workflows, it remains challenging at large scales. Here, we describe a major upgrade to eggNOG-mapper, a tool for functional annotation based on precomputed orthology assignmen...