Early brain development disruption from NMDA receptor hypofunction: Relevance to schizophrenia
Abstract Disruption to brain development at an early stage can potentially alter chemically coded neural networks and can affect behavior in later life. During early brain development antagonism of glutamate NMDA receptors, which play an important role in neuronal outgrowth and survival, leads to ne...
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| Published in | Brain Research Reviews Vol. 53; no. 2; pp. 260 - 270 |
|---|---|
| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
Amsterdam
Elsevier B.V
01.02.2007
Elsevier |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0165-0173 1872-6321 |
| DOI | 10.1016/j.brainresrev.2006.09.001 |
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| Abstract | Abstract Disruption to brain development at an early stage can potentially alter chemically coded neural networks and can affect behavior in later life. During early brain development antagonism of glutamate NMDA receptors, which play an important role in neuronal outgrowth and survival, leads to neuronal damage in several brain regions and causes behavioral alterations in rodents that mimic schizophrenia symptoms and endophenotypes. There are several lines of evidence implicating involvement of a dysfunctional glutamate system in schizophrenia. In normal subjects, NMDA receptor antagonists produce behavioral and neurochemical changes that mimic schizophrenia symptoms better than any other psychotomimetic drug. Moreover, these drugs worsen symptoms in schizophrenia patients and can trigger a recrudescence of the acute psychotic state in patients with stable chronic schizophrenia. In addition, genes consistently reported as being altered in schizophrenia play roles in development, neuroplasticity and glutamate/GABAergic neurotransmission. Perinatal NMDA receptor antagonist treatment is a useful model for studying the neurodevelopmental and NMDA receptor hypofunction hypotheses of schizophrenia because neurochemical and behavioral changes, reminiscent of those seen in schizophrenia, are present long after cessation of drug administration, which suggests that a permanent change in brain structure and organization has occurred during brain development. |
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| AbstractList | Disruption to brain development at an early stage can potentially alter chemically coded neural networks and can affect behavior in later life. During early brain development antagonism of glutamate NMDA receptors, which play an important role in neuronal outgrowth and survival, leads to neuronal damage in several brain regions and causes behavioral alterations in rodents that mimic schizophrenia symptoms and endophenotypes. There are several lines of evidence implicating involvement of a dysfunctional glutamate system in schizophrenia. In normal subjects, NMDA receptor antagonists produce behavioral and neurochemical changes that mimic schizophrenia symptoms better than any other psychotomimetic drug. Moreover, these drugs worsen symptoms in schizophrenia patients and can trigger a recrudescence of the acute psychotic state in patients with stable chronic schizophrenia. In addition, genes consistently reported as being altered in schizophrenia play roles in development, neuroplasticity and glutamate/GABAergic neurotransmission. Perinatal NMDA receptor antagonist treatment is a useful model for studying the neurodevelopmental and NMDA receptor hypofunction hypotheses of schizophrenia because neurochemical and behavioral changes, reminiscent of those seen in schizophrenia, are present long after cessation of drug administration, which suggests that a permanent change in brain structure and organization has occurred during brain development. Abstract Disruption to brain development at an early stage can potentially alter chemically coded neural networks and can affect behavior in later life. During early brain development antagonism of glutamate NMDA receptors, which play an important role in neuronal outgrowth and survival, leads to neuronal damage in several brain regions and causes behavioral alterations in rodents that mimic schizophrenia symptoms and endophenotypes. There are several lines of evidence implicating involvement of a dysfunctional glutamate system in schizophrenia. In normal subjects, NMDA receptor antagonists produce behavioral and neurochemical changes that mimic schizophrenia symptoms better than any other psychotomimetic drug. Moreover, these drugs worsen symptoms in schizophrenia patients and can trigger a recrudescence of the acute psychotic state in patients with stable chronic schizophrenia. In addition, genes consistently reported as being altered in schizophrenia play roles in development, neuroplasticity and glutamate/GABAergic neurotransmission. Perinatal NMDA receptor antagonist treatment is a useful model for studying the neurodevelopmental and NMDA receptor hypofunction hypotheses of schizophrenia because neurochemical and behavioral changes, reminiscent of those seen in schizophrenia, are present long after cessation of drug administration, which suggests that a permanent change in brain structure and organization has occurred during brain development. Disruption to brain development at an early stage can potentially alter chemically coded neural networks and can affect behavior in later life. During early brain development antagonism of glutamate NMDA receptors, which play an important role in neuronal outgrowth and survival, leads to neuronal damage in several brain regions and causes behavioral alterations in rodents that mimic schizophrenia symptoms and endophenotypes. There are several lines of evidence implicating involvement of a dysfunctional glutamate system in schizophrenia. In normal subjects, NMDA receptor antagonists produce behavioral and neurochemical changes that mimic schizophrenia symptoms better than any other psychotomimetic drug. Moreover, these drugs worsen symptoms in schizophrenia patients and can trigger a recrudescence of the acute psychotic state in patients with stable chronic schizophrenia. In addition, genes consistently reported as being altered in schizophrenia play roles in development, neuroplasticity and glutamate/GABAergic neurotransmission. Perinatal NMDA receptor antagonist treatment is a useful model for studying the neurodevelopmental and NMDA receptor hypofunction hypotheses of schizophrenia because neurochemical and behavioral changes, reminiscent of those seen in schizophrenia, are present long after cessation of drug administration, which suggests that a permanent change in brain structure and organization has occurred during brain development.Disruption to brain development at an early stage can potentially alter chemically coded neural networks and can affect behavior in later life. During early brain development antagonism of glutamate NMDA receptors, which play an important role in neuronal outgrowth and survival, leads to neuronal damage in several brain regions and causes behavioral alterations in rodents that mimic schizophrenia symptoms and endophenotypes. There are several lines of evidence implicating involvement of a dysfunctional glutamate system in schizophrenia. In normal subjects, NMDA receptor antagonists produce behavioral and neurochemical changes that mimic schizophrenia symptoms better than any other psychotomimetic drug. Moreover, these drugs worsen symptoms in schizophrenia patients and can trigger a recrudescence of the acute psychotic state in patients with stable chronic schizophrenia. In addition, genes consistently reported as being altered in schizophrenia play roles in development, neuroplasticity and glutamate/GABAergic neurotransmission. Perinatal NMDA receptor antagonist treatment is a useful model for studying the neurodevelopmental and NMDA receptor hypofunction hypotheses of schizophrenia because neurochemical and behavioral changes, reminiscent of those seen in schizophrenia, are present long after cessation of drug administration, which suggests that a permanent change in brain structure and organization has occurred during brain development. |
| Author | Huang, Xu-Feng du Bois, Teresa Marie |
| Author_xml | – sequence: 1 fullname: du Bois, Teresa Marie – sequence: 2 fullname: Huang, Xu-Feng |
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| Cites_doi | 10.1001/archpsyc.57.1.65 10.1016/S0920-9964(01)00188-8 10.1016/0920-9964(96)00024-2 10.1038/nm1418 10.1016/S0301-0082(97)00085-3 10.1016/S0306-4522(01)00384-0 10.1016/S0301-0082(97)00090-7 10.1007/BF02245123 10.1126/science.283.5398.70 10.1016/S0165-0173(00)00018-7 10.1016/S0006-2952(01)00696-7 10.1016/S0006-3223(97)00204-7 10.1016/S0736-5748(99)00069-6 10.1016/0022-3956(82)90038-3 10.1002/ana.410380116 10.1038/sj.mp.4001436 10.1016/S0014-2999(99)00070-9 10.1086/342734 10.1016/S0304-3940(98)00742-3 10.1210/endo-68-5-818 10.1002/1098-2396(200104)40:1<11::AID-SYN1021>3.0.CO;2-I 10.1034/j.1600-0447.2000.102006414.x 10.1016/0197-4580(83)90037-4 10.1016/0006-8993(93)90287-W 10.1523/JNEUROSCI.09-05-01693.1989 10.1038/368335a0 10.1016/S0278-5846(03)00146-5 10.1006/exnr.1998.6863 10.1126/science.1835799 10.1093/brain/122.4.593 10.1542/peds.87.4.431 10.1016/S0092-8674(00)81972-8 10.1038/sj.mp.4001384 10.1038/sj.mp.4001840 10.1016/S0165-3806(01)00126-2 10.1093/oxfordjournals.schbul.a033459 10.1046/j.1460-9568.2003.02902.x 10.1016/S0031-9384(97)00169-8 10.1523/JNEUROSCI.1086-05.2005 10.1016/S0140-6736(03)12379-3 10.1523/JNEUROSCI.18-14-05545.1998 10.1016/S0920-9964(98)00070-X 10.1124/jpet.102.041798 10.1001/archpsyc.1995.03950220015005 10.1037/0735-7044.111.1.49 10.1523/JNEUROSCI.23-03-00876.2003 10.1046/j.1460-9568.2003.02850.x 10.1176/appi.ajp.157.7.1141 10.1016/j.neuint.2006.01.019 10.1038/264705a0 10.1523/JNEUROSCI.2100-05.2005 10.1016/S0306-4522(01)00587-5 10.1016/j.bbr.2003.12.026 10.1016/0306-4522(95)00324-C 10.1016/S0165-3806(96)00204-0 10.1159/000017310 10.1126/science.166.3903.386 10.1002/1098-2396(200008)37:2<167::AID-SYN11>3.0.CO;2-B 10.1176/appi.ajp.161.4.742 10.1016/S0387-7604(97)00078-8 10.1016/j.schres.2004.11.011 10.1016/S0149-7634(03)00010-1 10.1176/appi.ajp.159.2.244 10.1016/j.pnpbp.2005.03.010 10.1016/0893-133X(95)00048-I 10.1086/345442 10.1038/sj.mp.4001348 10.1016/S0165-3806(00)00059-6 10.1126/science.8096653 10.1016/S0920-9964(01)00347-4 10.1016/0006-8993(94)91152-5 10.1016/0378-3782(79)90022-7 10.1016/0361-9230(96)00003-2 10.1016/0006-8993(95)00842-E 10.1016/0197-0186(95)00017-3 10.1046/j.1471-4159.1996.66031240.x 10.1016/j.ejphar.2003.08.105 10.1176/ajp.148.10.1301 10.1038/37795 10.1016/0014-2999(84)90453-9 10.1111/j.1469-8986.1978.tb01390.x 10.1016/0006-8993(92)90921-U 10.1146/annurev.ne.03.030180.001431 10.1016/S0006-3223(98)00281-9 10.1016/S0278-5846(03)00110-6 10.1046/j.1471-4159.2000.0740979.x 10.1016/0306-4522(94)90542-8 10.1016/j.nbd.2004.03.013 10.1080/07853890310017585 10.1016/0006-3223(93)90265-F 10.1016/0165-3806(93)90007-W 10.1016/S0925-4927(97)00012-7 10.1097/00001756-199704140-00034 10.1016/S0165-3806(98)00084-4 10.1006/exnr.1999.7126 10.1016/S0149-7634(03)00005-8 10.1046/j.1460-9568.2000.00189.x 10.1016/S0896-6273(03)00757-8 10.1001/archpsyc.1987.01800190080012 10.1038/13158 10.1097/00001756-199412000-00070 10.1523/JNEUROSCI.14-03-01358.1994 10.1016/j.biopsych.2004.11.031 10.1002/neu.480251105 10.2307/3454524 10.1002/(SICI)1097-4547(20000301)59:5<612::AID-JNR4>3.0.CO;2-V 10.1126/science.164.3880.719 10.1016/0165-3806(96)00094-6 10.1016/0169-328X(96)00051-4 10.1055/s-2007-979751 10.1093/hmg/ddl122 10.1016/S0022-3956(99)00029-1 10.1016/0304-3940(92)90307-S 10.1016/0014-5793(87)80525-2 10.1073/pnas.0630496100 10.1016/0892-0362(90)90107-N 10.1046/j.1471-4159.1997.68020469.x 10.1038/357686a0 10.1016/S0161-813X(01)00092-4 10.1016/S0736-5748(03)00026-1 10.1016/0014-4886(92)90185-S 10.1111/j.1750-3639.1996.tb00874.x 10.1073/pnas.88.22.10218 10.1016/j.neuroscience.2004.02.003 10.1016/0304-3940(80)90178-0 10.1016/S0165-0173(99)00041-7 10.1016/0306-4522(94)90248-8 10.1001/archpsyc.56.7.649 10.1093/schbul/15.3.477 10.1016/S0091-3057(03)00025-X 10.1038/sj.mp.4001377 10.1016/0022-3956(94)90009-4 10.1001/archpsyc.57.7.637 10.1002/jnr.490330413 10.1016/0006-3223(95)00046-1 |
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| Keywords | Schizophrenia NMDA receptor hypofunction Brain development Psychosis Central nervous system Development Early stage Glutamate receptor Review NMDA receptor Encephalon |
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| References | Allen, Frantom, Strauss, van Kammen (bib2) 2005; 75 Stefansson, Steinthorsdottir, Thorgeirsson, Gulcher, Stefansson (bib116) 2004; 36 Sircar, Soliman (bib110) 2003; 74 Gorter, Botterblom, Feenstra, Boer (bib46) 1992; 137 Jacobs, Taylor, Bardgett (bib61) 2000; 122 Olney (bib87) 2002; 23 Sharp, Williams (bib106) 1996; 39 Schmid, McGrath, Berechid, Boyles, Marchionni, Sestan, Anton (bib102) 2003; 100 Thompson, Sower, Perrone-Bizzozero (bib119) 1998; 43 Bear, Connors, Paradiso (bib7) 2007 Hulshoff Pol, Schnack, Bertens, van Haren, van der Tweel, Staal, Baare, Kahn (bib56) 2002; 159 Olney, Farber, Wozniak, Jevtovic-Todorovic, Ikonomidou (bib92) 2000; 108 Wangen, Myhrer, Moldstad, Iversen, Fonnum (bib128) 1997; 99 Facchinetti, Ciani, Dall'Olio, Virgili, Contestabile, Fonnum (bib29) 1993; 74 Ikonomidou, Price, Mosinger, Frierdich, Labruyere, Salles, Olney (bib58) 1989; 9 Castle, Sham, Murray (bib17) 1998; 33 Farrant, Feldmeyer, Takahashi, Cull-Candy (bib35) 1994; 368 Mohn, Gainetdinov, Caron, Koller (bib82) 1999; 98 Stefansson, Sarginson, Kong, Yates, Steinthorsdottir, Gudfinnsson, Gunnarsdottir, Walker, Petursson, Crombie, Ingason, Gulcher, Stefansson, St Clair (bib114) 2003; 72 Farber, Foster, Duhan, Olney (bib34) 1996; 21 Ozaki, Tohyama, Kishida, Buonanno, Yano, Hashikawa (bib94) 2000; 59 Harrison, Owen (bib52) 2003; 361 Volpe (bib123) 1997; 19 Latysheva, Rayevsky (bib72) 2003; 27 Selemon, Goldman-Rakic (bib103) 1999; 45 Glantz, Lewis (bib43) 2000; 57 Kitay (bib68) 1961; 68 Sircar (bib109) 2003; 21 Fredriksson, Archer, Alm, Gordh, Eriksson (bib39) 2004; 153 Contestabile (bib23) 2000; 32 Wang, McInnis, West, Bao, Anastasio, Guidry, Ye, Salvemini, Johnson (bib126) 2003; 304 Facchinetti, Dall'Olio, Ciani, Sparapani, Virgili, Contestabile (bib30) 1994; 60 Farber, Price, Labruyere, Nemnich, St. Peter, Wozniak, Olney (bib31) 1993; 34 Farber, Wozniak, Price, Labruyere, Huss, St. Peter, Olney (bib33) 1995; 38 Hahn, Wang, Cho, Talbot, Gur, Berrettini, Bakshi, Kamins, Borgmann-Winter, Siegel, Gallop, Arnold (bib18) 2006; 12 Tandon, Liu, Stafstrom, Sarkisian, Werner, Mikati, Yang, Holmes (bib117) 1996; 95 Blanchard, Blanchard, Carobrez Ade, Veniegas, Rodgers, Shepherd (bib10) 1992; 108 Eastwood, Harrison (bib27) 1995; 69 Gorter, de Bruin (bib45) 1992; 580 Weinberger (bib129) 1987; 44 Benes (bib8) 2000; 31 Keeney, Adcock, McArdle (bib65) 1991; 87 Semba, Tanaka, Wakuta, Suhara (bib105) 2001; 40 Ozawa, Kamiya, Tsuzuki (bib95) 1998; 54 Andersen (bib4) 2003; 27 Sircar, Follesa, Ticku (bib111) 1996; 40 Harrison (bib51) 1999; 122 Rapoport, Giedd, Blumenthal, Hamburger, Jeffries, Fernandez, Nicolson, Bedwell, Lenane, Zijdenbos, Paus, Evans (bib97) 1999; 56 Giedd, Blumenthal, Jeffries, Castellanos, Liu, Zijdenbos, Paus, Evans, Rapoport (bib41) 1999; 2 Wilson, Kinsman, Johnston (bib134) 1998; 109 Cirulli, Berry, Alleva (bib20) 2003; 27 Keshavan, Anderson, Pettergrew (bib66) 1994; 28 Walker, Bollini (bib124) 2002; 54 Stefansson, Thorgeirsson, Gulcher, Stefansson (bib115) 2003; 8 Vaskovsky, Lupowitz, Erlich, Pinkas-Kramarski (bib121) 2000; 74 Gould, Cameron (bib47) 1997; 111 Olney, Labruyere, Wang, Wozniak, Price, Sesma (bib90) 1991; 254 Giovannini, Mutolo, Bianchi, Michelassi, Pepeu (bib42) 1994; 14 Gu, Jiang, Fu, Ip, Yan (bib48) 2005; 25 Hwang, Kim, Ahn, Wie, Koh (bib57) 1999; 159 Tang, Chen, He, Zhou, Gu, Feng, He (bib118) 2004; 9 Mattson, Keller, Begley (bib78) 1998; 153 Frantz, Van Hartesveldt (bib38) 1999; 369 Gao, Sakai, Roberts, Conley, Dean, Tamminga (bib40) 2000; 157 Sharp, Butman, Wang, Koistinaho, Graham, Sagar, Noble, Berger, Longo (bib107) 1992; 33 Feinberg (bib36) 1982; 17 Kwon, Longart, Vullhorst, Hoffman, Buonanno (bib70) 2005; 25 Wenzel, Fritschy, Mohler, Benke (bib131) 1997; 68 Gorter, Brady (bib44) 1994; 665 Moghaddam (bib81) 2003; 40 Farber, Foster, Duhan, Olney (bib32) 1995; 12 DeLisi, Sakuma, Tew, Kushner, Hoff, Grimson (bib25) 1997; 74 Olney, Farber (bib88) 1994; 55 Wolf (bib135) 1998; 54 Li, Collier, He (bib75) 2006; 15 Andersen, Thompson, Rutstein, Hostetter, Teicher (bib6) 2000; 37 Wiley, Buhler, Lavecchia, Johnson (bib132) 2003; 27 Black, Kodish, Grossman, Klintsova, Orlovskaya, Vostrikov, Uranova, Greenough (bib9) 2004; 161 Van Lookeren Campagne, Vermeulen, Boer, Balazs (bib120) 1995; 27 Olney, Newcomer, Farber (bib91) 1999; 33 Ozaki, Sasner, Yano, Lu, Buonanno (bib93) 1997; 390 Collier, Li (bib21) 2003; 480 Olney, Sharpe (bib89) 1969; 166 Colwell, Cepeda, Crawford, Levine (bib22) 1998; 20 Ellison (bib28) 1994; 5 Amminger, Schlogelhofer, Lehner, Looser Ott, Friedrich, Aschauer (bib3) 2000; 102 Fix, Wozniak, Truex, McEwen, Miller, Olney (bib37) 1995; 696 Ritter, Unis, Meador-Woodruff (bib98) 2001; 127 Cador, Marco, Stinus, Simonnet (bib16) 2002; 110 Law, Weickert, Webster, Herman, Kleinman, Harrison (bib73) 2003; 18 Wenzel, Villa, Mohler, Benke (bib130) 1996; 66 Braff, Stone, Callaway, Geyer, Glick, Bali (bib11) 1978; 15 Lidow, Goldman-Rakic, Rakic (bib76) 1991; 88 Honack, Loscher (bib55) 1993; 620 Brooks, Weeks, Leboutillier, Petit (bib13) 1997; 62 Rosso, Bearden, Hollister, Gasperoni, Sanchez, Hadley, Cannon (bib100) 2000; 26 Selemon, Rajkowska, Goldman-Rakic (bib104) 1995; 52 Hoffman, Dobscha (bib54) 1989; 15 Meyer, Kotch, Riley (bib80) 1990; 12 Harris, Sharp, Gartlon, Jones, Harrison (bib50) 2003; 18 Lee, Choi (bib74) 1992; 118 Jevtovic-Todorovic, Hartman, Izumi, Benshoff, Dikranian, Zorumski, Olney, Wozniak (bib64) 2003; 23 Bubenikova-Valesova, Balcar, Tejkalova, Langmeier, St'astny (bib14) 2006; 48 Ikonomidou, Bosch, Miksa, Bittigau, Vockler, Dikranian, Tenkova, Stefovska, Turski, Olney (bib59) 1999; 283 Yang, Si, Ruan, Ling, Han, Wang, Zhou, Zhang, Kong, Liu, Zhang, Yu, Liu, Ju, Shu, Ma, Zhang (bib136) 2003; 8 Rivkin, Flax, Mozell, Osathanondh, Volpe, Villa-Komaroff (bib99) 1995; 38 Burek, Oppenheim (bib15) 1996; 6 Javitt, Zukin (bib63) 1991; 148 Nabeshima, Yamaguchi, Yamada, Hiramatsu, Kuwabara, Furukawa, Kameyama (bib85) 1984; 97 Stefansson, Sigurdsson, Steinthorsdottir, Bjornsdottir, Sigmundsson, Ghosh, Brynjolfsson, Gunnarsdottir, Ivarsson, Chou, Hjaltason, Birgisdottir, Jonsson, Gudnadottir, Gudmundsdottir, Bjornsson, Ingvarsson, Ingason, Sigfusson, Hardardottir, Harvey, Lai, Zhou, Brunner, Mutel, Gonzalo, Lemke, Sainz, Johannesson, Andresson, Gudbjartsson, Manolescu, Frigge, Gurney, Kong, Gulcher, Petursson, Stefansson (bib113) 2002; 71 Olney (bib86) 1969; 164 Wang, McInnis, Ross-Sanchez, Shinnick-Gallagher, Wiley, Johnson (bib125) 2001; 107 Dall'Olio, Facchinetti, Contestabile, Gandolfi (bib24) 1994; 63 Williams, Preece, Spurlock, Norton, Williams, Zammit, O'Donovan, Owen (bib133) 2003; 8 Adams, Moghaddam (bib1) 1998; 18 Andersen, Rutstein, Benzo, Hostetter, Teicher (bib5) 1997; 8 Rutherford, Pennock, Schwieso, Cowan, L.Dubwitz (bib101) 1995; 26 Changeux, Danchin (bib19) 1976; 264 Virgili, Facchinetti, Sparapani, Tregnago, Lucchi, Dall'Olio, Gandolfi, Contestabile (bib122) 1998; 258 McGlashan, Hoffman (bib79) 2000; 57 Brett, Chong, Coyle, Levine (bib12) 1983; 4 Pearce, Cambray-Deakin, Burgoyne (bib96) 1987; 223 Kim, Kornhuber, Schmid-Burgk, Holzmuller (bib67) 1980; 20 Monti, Contestabile (bib83) 2000; 12 Zhang, Reynolds (bib137) 2002; 55 Stefani, Moghaddam (bib112) 2005; 57 Wang, Anastasio, Popov, Leday, Johnson (bib127) 2004; 125 Sircar (bib108) 2000; 18 Landmesser (bib71) 1980; 3 Dobbing, Sands (bib26) 1979; 3 Jarskog, Glantz, Gilmore, Lieberman (bib62) 2005; 29 Lindholm, Castren, Berzaghi, Blochl, Thoenen (bib77) 1994; 25 Ikonomidou, Bittigau, Koch, Genz, Hoerster, Felderhoff-Mueser, Tenkova, Dikranian, Olney (bib60) 2001; 62 Hansen, Briem, Dzietko, Sifringer, Voss, Rzeski, Zdzisinska, Thor, Heumann, Stepulak (bib49) 2004; 16 Komuro, Rakic (bib69) 1993; 260 Hestrin (bib53) 1992; 357 Munafo, Thiselton, Clark, Flint (bib84) 2006; 11 Stefansson (10.1016/j.brainresrev.2006.09.001_bib115) 2003; 8 Zhang (10.1016/j.brainresrev.2006.09.001_bib137) 2002; 55 Jacobs (10.1016/j.brainresrev.2006.09.001_bib61) 2000; 122 Rutherford (10.1016/j.brainresrev.2006.09.001_bib101) 1995; 26 Olney (10.1016/j.brainresrev.2006.09.001_bib87) 2002; 23 Hansen (10.1016/j.brainresrev.2006.09.001_bib49) 2004; 16 Mohn (10.1016/j.brainresrev.2006.09.001_bib82) 1999; 98 Contestabile (10.1016/j.brainresrev.2006.09.001_bib23) 2000; 32 Semba (10.1016/j.brainresrev.2006.09.001_bib105) 2001; 40 Farrant (10.1016/j.brainresrev.2006.09.001_bib35) 1994; 368 Burek (10.1016/j.brainresrev.2006.09.001_bib15) 1996; 6 Wenzel (10.1016/j.brainresrev.2006.09.001_bib131) 1997; 68 Wang (10.1016/j.brainresrev.2006.09.001_bib127) 2004; 125 Williams (10.1016/j.brainresrev.2006.09.001_bib133) 2003; 8 Cirulli (10.1016/j.brainresrev.2006.09.001_bib20) 2003; 27 Vaskovsky (10.1016/j.brainresrev.2006.09.001_bib121) 2000; 74 Sircar (10.1016/j.brainresrev.2006.09.001_bib109) 2003; 21 Moghaddam (10.1016/j.brainresrev.2006.09.001_bib81) 2003; 40 Dobbing (10.1016/j.brainresrev.2006.09.001_bib26) 1979; 3 Tandon (10.1016/j.brainresrev.2006.09.001_bib117) 1996; 95 Ikonomidou (10.1016/j.brainresrev.2006.09.001_bib60) 2001; 62 Bubenikova-Valesova (10.1016/j.brainresrev.2006.09.001_bib14) 2006; 48 Ellison (10.1016/j.brainresrev.2006.09.001_bib28) 1994; 5 Gorter (10.1016/j.brainresrev.2006.09.001_bib46) 1992; 137 Ikonomidou (10.1016/j.brainresrev.2006.09.001_bib58) 1989; 9 Ozawa (10.1016/j.brainresrev.2006.09.001_bib95) 1998; 54 Thompson (10.1016/j.brainresrev.2006.09.001_bib119) 1998; 43 Stefansson (10.1016/j.brainresrev.2006.09.001_bib116) 2004; 36 Hwang (10.1016/j.brainresrev.2006.09.001_bib57) 1999; 159 Walker (10.1016/j.brainresrev.2006.09.001_bib124) 2002; 54 Cador (10.1016/j.brainresrev.2006.09.001_bib16) 2002; 110 Brooks (10.1016/j.brainresrev.2006.09.001_bib13) 1997; 62 Stefansson (10.1016/j.brainresrev.2006.09.001_bib113) 2002; 71 Changeux (10.1016/j.brainresrev.2006.09.001_bib19) 1976; 264 Gao (10.1016/j.brainresrev.2006.09.001_bib40) 2000; 157 Olney (10.1016/j.brainresrev.2006.09.001_bib90) 1991; 254 Tang (10.1016/j.brainresrev.2006.09.001_bib118) 2004; 9 Honack (10.1016/j.brainresrev.2006.09.001_bib55) 1993; 620 Lidow (10.1016/j.brainresrev.2006.09.001_bib76) 1991; 88 Colwell (10.1016/j.brainresrev.2006.09.001_bib22) 1998; 20 Sircar (10.1016/j.brainresrev.2006.09.001_bib111) 1996; 40 DeLisi (10.1016/j.brainresrev.2006.09.001_bib25) 1997; 74 Jarskog (10.1016/j.brainresrev.2006.09.001_bib62) 2005; 29 Wenzel (10.1016/j.brainresrev.2006.09.001_bib130) 1996; 66 Jevtovic-Todorovic (10.1016/j.brainresrev.2006.09.001_bib64) 2003; 23 Monti (10.1016/j.brainresrev.2006.09.001_bib83) 2000; 12 Sircar (10.1016/j.brainresrev.2006.09.001_bib108) 2000; 18 Wang (10.1016/j.brainresrev.2006.09.001_bib126) 2003; 304 Facchinetti (10.1016/j.brainresrev.2006.09.001_bib29) 1993; 74 Collier (10.1016/j.brainresrev.2006.09.001_bib21) 2003; 480 Gu (10.1016/j.brainresrev.2006.09.001_bib48) 2005; 25 Kim (10.1016/j.brainresrev.2006.09.001_bib67) 1980; 20 Landmesser (10.1016/j.brainresrev.2006.09.001_bib71) 1980; 3 Amminger (10.1016/j.brainresrev.2006.09.001_bib3) 2000; 102 Farber (10.1016/j.brainresrev.2006.09.001_bib31) 1993; 34 Stefani (10.1016/j.brainresrev.2006.09.001_bib112) 2005; 57 Ritter (10.1016/j.brainresrev.2006.09.001_bib98) 2001; 127 Stefansson (10.1016/j.brainresrev.2006.09.001_bib114) 2003; 72 Sharp (10.1016/j.brainresrev.2006.09.001_bib106) 1996; 39 Castle (10.1016/j.brainresrev.2006.09.001_bib17) 1998; 33 Munafo (10.1016/j.brainresrev.2006.09.001_bib84) 2006; 11 Braff (10.1016/j.brainresrev.2006.09.001_bib11) 1978; 15 Komuro (10.1016/j.brainresrev.2006.09.001_bib69) 1993; 260 Wangen (10.1016/j.brainresrev.2006.09.001_bib128) 1997; 99 Andersen (10.1016/j.brainresrev.2006.09.001_bib5) 1997; 8 Feinberg (10.1016/j.brainresrev.2006.09.001_bib36) 1982; 17 Mattson (10.1016/j.brainresrev.2006.09.001_bib78) 1998; 153 Allen (10.1016/j.brainresrev.2006.09.001_bib2) 2005; 75 Wang (10.1016/j.brainresrev.2006.09.001_bib125) 2001; 107 Pearce (10.1016/j.brainresrev.2006.09.001_bib96) 1987; 223 Kitay (10.1016/j.brainresrev.2006.09.001_bib68) 1961; 68 Benes (10.1016/j.brainresrev.2006.09.001_bib8) 2000; 31 Harrison (10.1016/j.brainresrev.2006.09.001_bib51) 1999; 122 McGlashan (10.1016/j.brainresrev.2006.09.001_bib79) 2000; 57 Weinberger (10.1016/j.brainresrev.2006.09.001_bib129) 1987; 44 Ikonomidou (10.1016/j.brainresrev.2006.09.001_bib59) 1999; 283 Gorter (10.1016/j.brainresrev.2006.09.001_bib44) 1994; 665 Selemon (10.1016/j.brainresrev.2006.09.001_bib103) 1999; 45 Wolf (10.1016/j.brainresrev.2006.09.001_bib135) 1998; 54 Brett (10.1016/j.brainresrev.2006.09.001_bib12) 1983; 4 Farber (10.1016/j.brainresrev.2006.09.001_bib33) 1995; 38 Olney (10.1016/j.brainresrev.2006.09.001_bib86) 1969; 164 Bear (10.1016/j.brainresrev.2006.09.001_bib7) 2007 Virgili (10.1016/j.brainresrev.2006.09.001_bib122) 1998; 258 Ozaki (10.1016/j.brainresrev.2006.09.001_bib93) 1997; 390 Lindholm (10.1016/j.brainresrev.2006.09.001_bib77) 1994; 25 Olney (10.1016/j.brainresrev.2006.09.001_bib89) 1969; 166 Wilson (10.1016/j.brainresrev.2006.09.001_bib134) 1998; 109 Meyer (10.1016/j.brainresrev.2006.09.001_bib80) 1990; 12 Lee (10.1016/j.brainresrev.2006.09.001_bib74) 1992; 118 Olney (10.1016/j.brainresrev.2006.09.001_bib92) 2000; 108 Hulshoff Pol (10.1016/j.brainresrev.2006.09.001_bib56) 2002; 159 Schmid (10.1016/j.brainresrev.2006.09.001_bib102) 2003; 100 Hoffman (10.1016/j.brainresrev.2006.09.001_bib54) 1989; 15 Keeney (10.1016/j.brainresrev.2006.09.001_bib65) 1991; 87 Keshavan (10.1016/j.brainresrev.2006.09.001_bib66) 1994; 28 Harris (10.1016/j.brainresrev.2006.09.001_bib50) 2003; 18 Wiley (10.1016/j.brainresrev.2006.09.001_bib132) 2003; 27 Sircar (10.1016/j.brainresrev.2006.09.001_bib110) 2003; 74 Dall'Olio (10.1016/j.brainresrev.2006.09.001_bib24) 1994; 63 Selemon (10.1016/j.brainresrev.2006.09.001_bib104) 1995; 52 Adams (10.1016/j.brainresrev.2006.09.001_bib1) 1998; 18 Li (10.1016/j.brainresrev.2006.09.001_bib75) 2006; 15 Black (10.1016/j.brainresrev.2006.09.001_bib9) 2004; 161 Andersen (10.1016/j.brainresrev.2006.09.001_bib6) 2000; 37 Olney (10.1016/j.brainresrev.2006.09.001_bib88) 1994; 55 Gould (10.1016/j.brainresrev.2006.09.001_bib47) 1997; 111 Javitt (10.1016/j.brainresrev.2006.09.001_bib63) 1991; 148 Volpe (10.1016/j.brainresrev.2006.09.001_bib123) 1997; 19 Nabeshima (10.1016/j.brainresrev.2006.09.001_bib85) 1984; 97 Frantz (10.1016/j.brainresrev.2006.09.001_bib38) 1999; 369 Law (10.1016/j.brainresrev.2006.09.001_bib73) 2003; 18 Yang (10.1016/j.brainresrev.2006.09.001_bib136) 2003; 8 Fix (10.1016/j.brainresrev.2006.09.001_bib37) 1995; 696 Rosso (10.1016/j.brainresrev.2006.09.001_bib100) 2000; 26 Kwon (10.1016/j.brainresrev.2006.09.001_bib70) 2005; 25 Blanchard (10.1016/j.brainresrev.2006.09.001_bib10) 1992; 108 Gorter (10.1016/j.brainresrev.2006.09.001_bib45) 1992; 580 Sharp (10.1016/j.brainresrev.2006.09.001_bib107) 1992; 33 Van Lookeren Campagne (10.1016/j.brainresrev.2006.09.001_bib120) 1995; 27 Hahn (10.1016/j.brainresrev.2006.09.001_bib18) 2006; 12 Giovannini (10.1016/j.brainresrev.2006.09.001_bib42) 1994; 14 Olney (10.1016/j.brainresrev.2006.09.001_bib91) 1999; 33 Farber (10.1016/j.brainresrev.2006.09.001_bib32) 1995; 12 Ozaki (10.1016/j.brainresrev.2006.09.001_bib94) 2000; 59 Farber (10.1016/j.brainresrev.2006.09.001_bib34) 1996; 21 Giedd (10.1016/j.brainresrev.2006.09.001_bib41) 1999; 2 Glantz (10.1016/j.brainresrev.2006.09.001_bib43) 2000; 57 Rivkin (10.1016/j.brainresrev.2006.09.001_bib99) 1995; 38 Rapoport (10.1016/j.brainresrev.2006.09.001_bib97) 1999; 56 Fredriksson (10.1016/j.brainresrev.2006.09.001_bib39) 2004; 153 Facchinetti (10.1016/j.brainresrev.2006.09.001_bib30) 1994; 60 Harrison (10.1016/j.brainresrev.2006.09.001_bib52) 2003; 361 Latysheva (10.1016/j.brainresrev.2006.09.001_bib72) 2003; 27 Eastwood (10.1016/j.brainresrev.2006.09.001_bib27) 1995; 69 Andersen (10.1016/j.brainresrev.2006.09.001_bib4) 2003; 27 Hestrin (10.1016/j.brainresrev.2006.09.001_bib53) 1992; 357 |
| References_xml | – volume: 40 start-page: 11 year: 2001 end-page: 18 ident: bib105 article-title: Neonatal phencyclidine treatment selectively attenuates mesolimbic dopamine function in adult rats as revealed by methamphetamine-induced behavior and c- publication-title: Synapse – volume: 9 start-page: 11 year: 2004 end-page: 12 ident: bib118 article-title: Polymorphisms within 5′ end of the Neuregulin 1 gene are genetically associated with schizophrenia in the Chinese population publication-title: Molecular Psychiatry – volume: 33 start-page: 179 year: 1998 end-page: 183 ident: bib17 article-title: Differences in distribution of ages of onset in males and females with schizophrenia publication-title: Schizophrenia Research – volume: 45 start-page: 17 year: 1999 end-page: 25 ident: bib103 article-title: The reduced neuropil hypothesis: a circuit based model of schizophrenia publication-title: Biological Psychiatry – volume: 62 start-page: 955 year: 1997 end-page: 962 ident: bib13 article-title: Altered NMDA sensitivity and learning following chronic developmental NMDA antagonism publication-title: Physiology and Behavior – volume: 157 start-page: 1141 year: 2000 end-page: 1149 ident: bib40 article-title: Ionotropic glutamate receptors and expression of publication-title: American Journal of Psychiatry – volume: 127 start-page: 123 year: 2001 end-page: 133 ident: bib98 article-title: Ontogeny of ionotropic glutamate receptor expression in human fetal brain publication-title: Developmental Brain Research – volume: 12 start-page: 15 year: 1990 end-page: 22 ident: bib80 article-title: Neonatal ethanol exposure: functional alterations associated with cerebellar growth retardation publication-title: Neurotoxicology and Teratology – volume: 304 start-page: 266 year: 2003 end-page: 271 ident: bib126 article-title: Blockade of phencyclidine-induced cortical apoptosis and deficits in prepulse inhibition by M40403, a superoxide dismutase mimetic publication-title: The Journal of Pharmacology and Experimental Therapeutics – volume: 66 start-page: 1240 year: 1996 end-page: 1248 ident: bib130 article-title: Developmental and regional expression of NMDA receptor subtypes containing the NR2D subunit in rat brain publication-title: Journal of Neurochemistry – volume: 3 start-page: 279 year: 1980 end-page: 302 ident: bib71 article-title: The Generation of Neuromuscular Specificity publication-title: Annual Review of Neuroscience – volume: 15 start-page: 477 year: 1989 end-page: 490 ident: bib54 article-title: Cortical pruning and the development of schizophrenia: a computer model publication-title: Schizophrenia Bulletin – volume: 159 start-page: 244 year: 2002 end-page: 250 ident: bib56 article-title: Volume changes in gray matter in patients with schizophrenia publication-title: American Journal of Psychiatry – volume: 43 start-page: 239 year: 1998 end-page: 243 ident: bib119 article-title: Altered levels of the synaptosomal associated protein SNAP-25 in schizophrenia publication-title: Biological Psychiatry – volume: 68 start-page: 469 year: 1997 end-page: 478 ident: bib131 article-title: NMDA receptor heterogeneity during postnatal development of the rat brain: differential expression of the NR2A, NR2B, and NR2C subunit proteins publication-title: Journal of Neurochemistry – volume: 15 start-page: 339 year: 1978 end-page: 343 ident: bib11 article-title: Prestimulus effects on human startle reflex in normals and schizophrenics publication-title: Psychophysiology – volume: 164 start-page: 719 year: 1969 end-page: 721 ident: bib86 article-title: Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate publication-title: Science – volume: 665 start-page: 63 year: 1994 end-page: 68 ident: bib44 article-title: NMDA receptor responses in adult hippocampal CA1 region after neonatal treatment with MK-801: comparison with NMDA receptor responses in the immature rat publication-title: Brain Research – volume: 110 start-page: 309 year: 2002 end-page: 318 ident: bib16 article-title: Interaction between neuropeptide FF and opioids in the ventral tegmental area in the behavioral response to novelty publication-title: Neuroscience – volume: 27 start-page: 3 year: 2003 end-page: 18 ident: bib4 article-title: Trajectories of brain development: point of vulnerability or window of opportunity? publication-title: Neuroscience and Biobehavioral Reviews – volume: 8 start-page: 485 year: 2003 end-page: 487 ident: bib133 article-title: Support for genetic variation in neuregulin 1 and susceptibility to schizophrenia publication-title: Molecular Psychiatry – volume: 57 start-page: 65 year: 2000 end-page: 73 ident: bib43 article-title: Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia publication-title: Archives of General Psychiatry – volume: 148 start-page: 1301 year: 1991 end-page: 1308 ident: bib63 article-title: Recent advances in the phencyclidine model of schizophrenia publication-title: American Journal of Psychiatry – volume: 33 start-page: 605 year: 1992 end-page: 616 ident: bib107 article-title: Haloperidol prevents induction of the hsp70 heat shock gene in neurons injured by phencyclidine (PCP), MK801, and ketamine publication-title: Journal of Neuroscience Research – volume: 25 start-page: 9378 year: 2005 end-page: 9383 ident: bib70 article-title: Neuregulin-1 reverses long-term potentiation at CA1 hippocampal synapses publication-title: Journal of Neuroscience – volume: 74 start-page: 979 year: 2000 end-page: 987 ident: bib121 article-title: ErbB-4 activation promotes neurite outgrowth in PC12 cells publication-title: Journal of Neurochemistry – volume: 18 start-page: 1197 year: 2003 end-page: 1205 ident: bib73 article-title: Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation publication-title: European Journal of Neuroscience – volume: 111 start-page: 49 year: 1997 end-page: 56 ident: bib47 article-title: Early NMDA receptor blockade impairs defensive behavior and increases cell proliferation in the dentate gyrus of developing rats publication-title: Behavioral Neuroscience – volume: 8 start-page: 706 year: 2003 end-page: 709 ident: bib136 article-title: Association study of neuregulin 1 gene with schizophrenia publication-title: Molecular Psychiatry – volume: 18 start-page: 121 year: 2000 end-page: 131 ident: bib108 article-title: Developmental maturation of the publication-title: International Journal of Developmental Neuroscience – volume: 36 start-page: 62 year: 2004 end-page: 71 ident: bib116 article-title: Neuregulin 1 and schizophrenia publication-title: Annals of Medicine – volume: 264 start-page: 705 year: 1976 end-page: 712 ident: bib19 article-title: Selective stabilisation of developing synapses as a mechanism for the specification of neuronal networks publication-title: Nature – volume: 20 start-page: 379 year: 1980 end-page: 382 ident: bib67 article-title: Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia publication-title: Neuroscience Letters – volume: 25 start-page: 4974 year: 2005 end-page: 4984 ident: bib48 article-title: Regulation of NMDA receptors by neuregulin signaling in prefrontal cortex publication-title: Journal of Neuroscience – volume: 98 start-page: 427 year: 1999 end-page: 436 ident: bib82 article-title: Mice with reduced NMDA receptor expression display behaviors related to schizophrenia publication-title: Cell – volume: 153 start-page: 367 year: 2004 end-page: 376 ident: bib39 article-title: Neurofunctional deficits and potentiated apoptosis by neonatal NMDA antagonist administration publication-title: Behavioural Brain Research – volume: 26 start-page: 183 year: 1995 end-page: 191 ident: bib101 article-title: Hypoxic ischaemic encephalopathy: early magnetc resonance imaging findings and their evolution publication-title: Neuropediatrics – volume: 72 start-page: 83 year: 2003 end-page: 87 ident: bib114 article-title: Association of neuregulin 1 with schizophrenia confirmed in a Scottish population publication-title: American Journal of Human Genetics – volume: 122 start-page: 91 year: 2000 end-page: 95 ident: bib61 article-title: Maturation of locomotor and Fos responses to the NMDA antagonists, PCP and MK-801 publication-title: Developmental Brain Research – volume: 17 start-page: 319 year: 1982 end-page: 334 ident: bib36 article-title: Schizophrenia: caused by a fault in programmed synaptic elimination during adolescence? publication-title: Journal of Psychiatric Research – volume: 40 start-page: 881 year: 2003 end-page: 884 ident: bib81 article-title: Bringing order to the glutamate chaos in schizophrenia publication-title: Neuron – volume: 11 start-page: 613 year: 2006 ident: bib84 article-title: Association of the NRG1 gene and schizophrenia: a meta-analysis publication-title: Molecular Psychiatry – volume: 63 start-page: 451 year: 1994 end-page: 455 ident: bib24 article-title: Chronic neonatal blockade of publication-title: Neuroscience – volume: 19 start-page: 519 year: 1997 end-page: 534 ident: bib123 article-title: Brain injury in the premature infant—From pathogenesis to prevention publication-title: Brain Development – volume: 260 start-page: 95 year: 1993 end-page: 97 ident: bib69 article-title: Modulation of neuronal migration by NMDA receptors publication-title: Science – volume: 100 start-page: 4251 year: 2003 end-page: 4256 ident: bib102 article-title: Neuregulin 1-erbB2 signaling is required for the establishment of radial glia and their transformation into astrocytes in cerebral cortex publication-title: PNAS – volume: 696 start-page: 194 year: 1995 end-page: 204 ident: bib37 article-title: Quantitative analysis of factors influencing neuronal necrosis induced by MK-801 in the rat posterior cingulate/retrosplenial cortex publication-title: Brain Research – volume: 21 start-page: 159 year: 2003 end-page: 167 ident: bib109 article-title: Postnatal phencyclidine-induced deficit in adult water maze performance is associated with publication-title: International Journal of Developmental Neuroscience – volume: 107 start-page: 535 year: 2001 end-page: 550 ident: bib125 article-title: Long-term behavioral and neurodegenerative effects of perinatal phencyclidine administration: implications for schizophrenia publication-title: Neuroscience – volume: 357 start-page: 686 year: 1992 end-page: 689 ident: bib53 article-title: Developmental regulation of NMDA receptor-mediated synaptic currents at a central synapse publication-title: Nature – volume: 74 start-page: 219 year: 1993 end-page: 224 ident: bib29 article-title: Structural, neurochemical and behavioural consequences of neonatal blockade of NMDA receptor through chronic treatment with CGP 39551 or MK-801 publication-title: Developmental Brain Research – volume: 87 start-page: 431 year: 1991 end-page: 438 ident: bib65 article-title: Prospective observations of 100 high-risk neonates by high-field (1.5 Telsa) magnetic resonance imaging of the central nervous system: II. Lesions associated with hypoxic-Ischemic encephalopathy publication-title: Pediatrics – volume: 52 start-page: 805 year: 1995 end-page: 818 ident: bib104 article-title: Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17 publication-title: Archives of General Psychiatry – volume: 12 start-page: 347 year: 1995 end-page: 349 ident: bib32 article-title: alpha 2 adrenergic agonists prevent MK-801 neurotoxicity publication-title: Neuropsychopharmacology – volume: 38 start-page: 788 year: 1995 end-page: 796 ident: bib33 article-title: Age-specific neurotoxicity in the rat associated with NMDA receptor blockade: potential relevance to schizophrenia? publication-title: Biological Psychiatry – volume: 44 start-page: 660 year: 1987 end-page: 669 ident: bib129 article-title: Implications of normal brain development for the pathogenesis of schizophrenia publication-title: Archives of General Psychiatry – volume: 12 start-page: 3117 year: 2000 end-page: 3123 ident: bib83 article-title: Blockade of the NMDA receptor increases developmental apoptotic elimination of granule neurons and activates caspases in the rat cerebellum publication-title: European Journal of Neuroscience – volume: 28 start-page: 239 year: 1994 end-page: 265 ident: bib66 article-title: Is Schizophrenia due to excessive synaptic pruning in the prefrontal cortex? The Feinberg hypothesis revisited publication-title: Journal of Psychiatric Research – volume: 4 start-page: 133 year: 1983 end-page: 138 ident: bib12 article-title: The pituitary–adrenal response to novel stimulation and ether stress in young adult and aged rats publication-title: Neurobiology of Aging – volume: 580 start-page: 12 year: 1992 end-page: 17 ident: bib45 article-title: Chronic neonatal MK-801 treatment results in an impairment of spatial learning in the adult rat publication-title: Brain Research – volume: 6 start-page: 427 year: 1996 end-page: 446 ident: bib15 article-title: Programmed cell death in the developing nervous system publication-title: Brain Pathology – volume: 118 start-page: 284 year: 1992 end-page: 290 ident: bib74 article-title: Density and distribution of excitatory amino acid receptors in the developing human fetal brain: a quantitative autoradiographic study publication-title: Experimental Neurology – volume: 38 start-page: 92 year: 1995 end-page: 101 ident: bib99 article-title: Oligodendroglial development in human fetal cerebrum publication-title: Annals of Neurology – volume: 3 start-page: 79 year: 1979 end-page: 83 ident: bib26 article-title: Comparative aspects of the brain growth spurt publication-title: Early Human Development – volume: 2 start-page: 861 year: 1999 end-page: 863 ident: bib41 article-title: Brain development during childhood and adolescence: a longitudinal MRI study publication-title: Nature Neuroscience – volume: 480 start-page: 177 year: 2003 end-page: 184 ident: bib21 article-title: The genetics of schizophrenia: glutamate not dopamine? publication-title: European Journal of Pharmacology – volume: 16 start-page: 440 year: 2004 end-page: 453 ident: bib49 article-title: Mechanisms leading to disseminated apoptosis following NMDA receptor blockade in the developing rat brain publication-title: Neurobiology of Disease – volume: 108 start-page: 383 year: 2000 end-page: 388 ident: bib92 article-title: Environmental agents that have the potential to trigger massive apoptotic neurodegeneration in the developing brain publication-title: Environmental Health Perspectives – volume: 99 start-page: 126 year: 1997 end-page: 130 ident: bib128 article-title: Modulatory treatment of NMDA receptors in neonatal rats affects cognitive behavior in adult age publication-title: Developmental Brain Research – volume: 390 start-page: 691 year: 1997 end-page: 694 ident: bib93 article-title: Neuregulin-beta induces expression of an NMDA-receptor subunit publication-title: Nature – volume: 108 start-page: 352 year: 1992 end-page: 362 ident: bib10 article-title: MK-801 produces a reduction in anxiety-related antipredator defensiveness in male and female rats and a gender-dependent increase in locomotor behavior publication-title: Psychopharmacology – volume: 68 start-page: 818 year: 1961 end-page: 824 ident: bib68 article-title: Sex differences in adrenal cortical secretion in the rat publication-title: Endocrinology – volume: 54 start-page: 17 year: 2002 end-page: 23 ident: bib124 article-title: Pubertal neurodevelopment and the emergence of psychotic symptoms publication-title: Schizophrenia Research – volume: 37 start-page: 167 year: 2000 end-page: 169 ident: bib6 article-title: Dopamine receptor pruning in prefrontal cortex during the periadolescent period in rats publication-title: Synapse – year: 2007 ident: bib7 article-title: Neuroscience: Exploring the Brain – volume: 18 start-page: 5545 year: 1998 end-page: 5554 ident: bib1 article-title: Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine publication-title: Journal of Neuroscience – volume: 31 start-page: 251 year: 2000 end-page: 269 ident: bib8 article-title: Emerging principles of altered neural circuitry in schizophrenia publication-title: Brain Research Reviews – volume: 55 start-page: 43 year: 1994 end-page: 46 ident: bib88 article-title: Efficacy of clozapine compared with other antipsychotics in preventing NMDA-antagonist neurotoxicity publication-title: Journal of Clinical Psychiatry – volume: 54 start-page: 581 year: 1998 end-page: 618 ident: bib95 article-title: Glutamate receptors in the mammalian central nervous system publication-title: Progress in Neurobiology – volume: 26 start-page: 367 year: 2000 end-page: 378 ident: bib100 article-title: Childhood neuromotor dysfunction in schizophrenia patients and their unaffected siblings: a prospective cohort study publication-title: Schizophrenia Bulletin – volume: 161 start-page: 742 year: 2004 end-page: 744 ident: bib9 article-title: Pathology of layer V pyramidal neurons in the prefrontal cortex of patients with schizophrenia publication-title: American Journal of Psychiatry – volume: 27 start-page: 73 year: 2003 end-page: 82 ident: bib20 article-title: Early disruption of the mother-infant relationship: effects on brain plasticity and implications for psychopathology publication-title: Neuroscience and Biobehavioral Reviews – volume: 34 start-page: 119 year: 1993 end-page: 121 ident: bib31 article-title: Antipsychotic drugs block phencyclidine receptor-mediated neurotoxicity publication-title: Biological Psychiatry – volume: 159 start-page: 124 year: 1999 end-page: 130 ident: bib57 publication-title: Experimental Neurology – volume: 74 start-page: 943 year: 2003 end-page: 952 ident: bib110 article-title: Effects of postnatal PCP treatment on locomotor behavior and striatal D2 receptor publication-title: Pharmacology Biochemistry and Behavior – volume: 109 start-page: 211 year: 1998 end-page: 220 ident: bib134 article-title: Expression of NMDA receptor subunit mRNA after MK-801 treatment in neonatal rats publication-title: Developmental Brain Research – volume: 368 start-page: 335 year: 1994 end-page: 339 ident: bib35 article-title: NMDA-receptor channel diversity in the developing cerebellum publication-title: Nature – volume: 60 start-page: 343 year: 1994 end-page: 353 ident: bib30 article-title: Long-lasting effects of chronic neonatal blockade of publication-title: Neuroscience – volume: 57 start-page: 637 year: 2000 end-page: 648 ident: bib79 article-title: Schizophrenia as a disorder of developmentally reduced synaptic connectivity publication-title: Archives of General Psychiatry – volume: 8 start-page: 639 year: 2003 end-page: 640 ident: bib115 article-title: Neuregulin 1 in schizophrenia: out of Iceland publication-title: Molecular Psychiatry – volume: 74 start-page: 129 year: 1997 end-page: 140 ident: bib25 article-title: Schizophrenia as a chronic active brain process: a study of progressive brain structural change subsequent to the onset of schizophrenia publication-title: Psychiatry Research – volume: 153 start-page: 35 year: 1998 end-page: 48 ident: bib78 article-title: Evidence for synaptic apoptosis publication-title: Experimental Neurology – volume: 18 start-page: 1706 year: 2003 end-page: 1710 ident: bib50 article-title: Long-term behavioural, molecular and morphological effects of neonatal NMDA receptor antagonism publication-title: European Journal of Neuroscience – volume: 361 start-page: 417 year: 2003 end-page: 419 ident: bib52 article-title: Genes for schizophrenia? Recent findings and their pathophysiological implications publication-title: Lancet – volume: 27 start-page: 867 year: 2003 end-page: 873 ident: bib132 article-title: Pharmacological challenge reveals long-term effects of perinatal phencyclidine on delayed spatial alternation in rats publication-title: Progress in Neuro-Psychopharmacology and Biological Psychiatry – volume: 27 start-page: 355 year: 1995 end-page: 366 ident: bib120 article-title: Treatment with NMDA receptor antagonists does not affect developmental changes in NMDA receptor properties in vivo publication-title: Neurochemistry International – volume: 20 start-page: 154 year: 1998 ident: bib22 article-title: Postnatal development of glutamate receptor-mediated responses in the neostriatum publication-title: Developmental Neuroscience – volume: 14 start-page: 1358 year: 1994 end-page: 1365 ident: bib42 article-title: NMDA receptor antagonists decrease GABA outflow from the septum and increase acetylcholine outflow from the hippocampus: a microdialysis study publication-title: Journal of Neuroscience – volume: 33 start-page: 523 year: 1999 end-page: 533 ident: bib91 article-title: NMDA receptor hypofunction model of schizophrenia publication-title: Journal of Psychiatric Research – volume: 125 start-page: 473 year: 2004 end-page: 483 ident: bib127 article-title: Blockade of publication-title: Neuroscience – volume: 25 start-page: 1362 year: 1994 end-page: 1372 ident: bib77 article-title: Activity-dependent and hormonal regulation of neurotrophin mRNA levels in the brain—Implications for neuronal plasticity publication-title: Journal of Neurobiology – volume: 122 start-page: 593 year: 1999 end-page: 624 ident: bib51 article-title: The neuropathology of schizophrenia. A critical review of the data and their interpretation publication-title: Brain – volume: 254 start-page: 1515 year: 1991 end-page: 1518 ident: bib90 article-title: NMDA antagonist neurotoxicity: mechanism and prevention publication-title: Science – volume: 40 start-page: 214 year: 1996 end-page: 220 ident: bib111 article-title: Postnatal phencyclidine treatment differentially regulates publication-title: Molecular Brain Research – volume: 9 start-page: 1693 year: 1989 end-page: 1700 ident: bib58 article-title: Hypobaric–ischemic conditions produce glutamate-like cytopathology in infant rat brain publication-title: Journal of Neuroscience – volume: 258 start-page: 1 year: 1998 end-page: 4 ident: bib122 article-title: Neuronal nitric oxide synthase is permanently decreased in the cerebellum of rats subjected to chronic neonatal blockade of publication-title: Neuroscience Letters – volume: 23 start-page: 876 year: 2003 end-page: 882 ident: bib64 article-title: Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits publication-title: Journal of Neuroscience – volume: 56 start-page: 649 year: 1999 end-page: 654 ident: bib97 article-title: Progressive cortical change during adolescence in childhood-onset schizophrenia. A longitudinal magnetic resonance imaging study publication-title: Archives of General Psychiatry – volume: 8 start-page: 1495 year: 1997 end-page: 1498 ident: bib5 article-title: Sex differences in dopamine receptor overproduction and elimination publication-title: NeuroReport – volume: 27 start-page: 787 year: 2003 end-page: 794 ident: bib72 article-title: Chronic neonatal publication-title: Progress in Neuro-Psychopharmacology and Biological Psychiatry – volume: 21 start-page: 33 year: 1996 end-page: 37 ident: bib34 article-title: Olanzapine and fluperlapine mimic clozapine in preventing MK-801 neurotoxicity publication-title: Schizophrenia Research – volume: 369 start-page: 145 year: 1999 end-page: 157 ident: bib38 article-title: Locomotion elicited by MK801 in developing and adult rats: temporal, environmental, and gender effects publication-title: European Journal of Pharmacology – volume: 95 start-page: 256 year: 1996 end-page: 262 ident: bib117 article-title: Long-term effects of excitatory amino acid antagonists NBQX and MK-801 on the developing brain publication-title: Developmental Brain Research – volume: 48 start-page: 515 year: 2006 end-page: 522 ident: bib14 article-title: Neonatal administration of publication-title: Neurochemistry International – volume: 15 start-page: 1995 year: 2006 end-page: 2002 ident: bib75 article-title: Meta-analysis shows strong positive association of the neuregulin 1 (NRG1) gene with schizophrenia publication-title: Human Molecular Genetics – volume: 75 start-page: 389 year: 2005 end-page: 397 ident: bib2 article-title: Differential patterns of premorbid academic and social deterioration in patients with schizophrenia publication-title: Schizophrenia Research – volume: 39 start-page: 359 year: 1996 end-page: 366 ident: bib106 article-title: Effects of sigma ligands on the ability of rimcazole to inhibit PCP hsp70 induction publication-title: Brain Research Bulletin – volume: 59 start-page: 612 year: 2000 end-page: 623 ident: bib94 article-title: Roles of neuregulin in synaptogenesis between mossy fibers and cerebellar granule cells publication-title: Journal of Neuroscience Research – volume: 620 start-page: 167 year: 1993 end-page: 170 ident: bib55 article-title: Sex differences in NMDA receptor mediated responses in rats publication-title: Brain Research – volume: 55 start-page: 1 year: 2002 end-page: 10 ident: bib137 article-title: A selective decrease in the relative density of parvalbumin-immunoreactive neurons in the hippocampus in schizophrenia publication-title: Schizophrenia Research – volume: 283 start-page: 70 year: 1999 end-page: 74 ident: bib59 article-title: Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain publication-title: Science – volume: 54 start-page: 679 year: 1998 end-page: 720 ident: bib135 article-title: The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants publication-title: Progress in Neurobiology – volume: 71 start-page: 877 year: 2002 end-page: 892 ident: bib113 article-title: Neuregulin 1 and susceptibility to schizophrenia publication-title: American Journal of Human Genetics – volume: 23 start-page: 659 year: 2002 end-page: 668 ident: bib87 article-title: New insights and new issues in developmental neurotoxicology publication-title: NeuroToxicology – volume: 62 start-page: 401 year: 2001 end-page: 405 ident: bib60 article-title: Neurotransmitters and apoptosis in the developing brain publication-title: Biochemical Pharmacology – volume: 137 start-page: 97 year: 1992 end-page: 100 ident: bib46 article-title: Chronic neonatal NMDA receptor blockade with MK-801 alters monoamine metabolism in the adult rat publication-title: Neuroscience Letters – volume: 223 start-page: 143 year: 1987 end-page: 147 ident: bib96 article-title: Glutamate acting on NMDA receptors stimulates neurite outgrowth from cerebellar granule cells publication-title: FEBS Letters – volume: 5 start-page: 2688 year: 1994 end-page: 2692 ident: bib28 article-title: Competitive and non-competitive NMDA antagonists induce similar limbic degeneration publication-title: NeuroReport – volume: 97 start-page: 217 year: 1984 end-page: 227 ident: bib85 article-title: Sex-dependent differences in the pharmacological actions and pharmacokinetics of phencyclidine in rats publication-title: European Journal of Pharmacology – volume: 32 start-page: 476 year: 2000 end-page: 509 ident: bib23 article-title: Roles of NMDA receptor activity and nitric oxide production in brain development publication-title: Brain Research Reviews – volume: 57 start-page: 433 year: 2005 end-page: 436 ident: bib112 article-title: Transient publication-title: Biological Psychiatry – volume: 166 start-page: 386 year: 1969 end-page: 388 ident: bib89 article-title: Brain lesions in an infant rhesus monkey treated with nonsodium glutamate publication-title: Science – volume: 88 start-page: 10218 year: 1991 end-page: 10221 ident: bib76 article-title: Synchronized overproduction of neurotransmitter receptors in diverse regions of the primate cerebral cortex publication-title: Proceedings of the National Academy of Sciences of the United States of America – volume: 12 start-page: 824 year: 2006 end-page: 828 ident: bib18 article-title: Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia publication-title: Nature Medicine – volume: 69 start-page: 339 year: 1995 end-page: 343 ident: bib27 article-title: Decreased synaptophysin in the medial temporal lobe in schizophrenia demonstrated using immunoautoradiography publication-title: Neuroscience – volume: 102 start-page: 414 year: 2000 end-page: 422 ident: bib3 article-title: Premorbid performance IQ deficit in schizophrenia publication-title: Acta Psychiatrica Scandinavica – volume: 29 start-page: 846 year: 2005 end-page: 858 ident: bib62 article-title: Apoptotic mechanisms in the pathophysiology of schizophrenia publication-title: Progress in Neuro-Psychopharmacology and Biological Psychiatry – volume: 57 start-page: 65 year: 2000 ident: 10.1016/j.brainresrev.2006.09.001_bib43 article-title: Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia publication-title: Archives of General Psychiatry doi: 10.1001/archpsyc.57.1.65 – volume: 55 start-page: 1 year: 2002 ident: 10.1016/j.brainresrev.2006.09.001_bib137 article-title: A selective decrease in the relative density of parvalbumin-immunoreactive neurons in the hippocampus in schizophrenia publication-title: Schizophrenia Research doi: 10.1016/S0920-9964(01)00188-8 – volume: 21 start-page: 33 year: 1996 ident: 10.1016/j.brainresrev.2006.09.001_bib34 article-title: Olanzapine and fluperlapine mimic clozapine in preventing MK-801 neurotoxicity publication-title: Schizophrenia Research doi: 10.1016/0920-9964(96)00024-2 – volume: 12 start-page: 824 year: 2006 ident: 10.1016/j.brainresrev.2006.09.001_bib18 article-title: Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia publication-title: Nature Medicine doi: 10.1038/nm1418 – volume: 54 start-page: 581 year: 1998 ident: 10.1016/j.brainresrev.2006.09.001_bib95 article-title: Glutamate receptors in the mammalian central nervous system publication-title: Progress in Neurobiology doi: 10.1016/S0301-0082(97)00085-3 – volume: 107 start-page: 535 year: 2001 ident: 10.1016/j.brainresrev.2006.09.001_bib125 article-title: Long-term behavioral and neurodegenerative effects of perinatal phencyclidine administration: implications for schizophrenia publication-title: Neuroscience doi: 10.1016/S0306-4522(01)00384-0 – volume: 54 start-page: 679 year: 1998 ident: 10.1016/j.brainresrev.2006.09.001_bib135 article-title: The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants publication-title: Progress in Neurobiology doi: 10.1016/S0301-0082(97)00090-7 – volume: 108 start-page: 352 year: 1992 ident: 10.1016/j.brainresrev.2006.09.001_bib10 article-title: MK-801 produces a reduction in anxiety-related antipredator defensiveness in male and female rats and a gender-dependent increase in locomotor behavior publication-title: Psychopharmacology doi: 10.1007/BF02245123 – volume: 283 start-page: 70 year: 1999 ident: 10.1016/j.brainresrev.2006.09.001_bib59 article-title: Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain publication-title: Science doi: 10.1126/science.283.5398.70 – volume: 32 start-page: 476 year: 2000 ident: 10.1016/j.brainresrev.2006.09.001_bib23 article-title: Roles of NMDA receptor activity and nitric oxide production in brain development publication-title: Brain Research Reviews doi: 10.1016/S0165-0173(00)00018-7 – volume: 62 start-page: 401 year: 2001 ident: 10.1016/j.brainresrev.2006.09.001_bib60 article-title: Neurotransmitters and apoptosis in the developing brain publication-title: Biochemical Pharmacology doi: 10.1016/S0006-2952(01)00696-7 – volume: 43 start-page: 239 year: 1998 ident: 10.1016/j.brainresrev.2006.09.001_bib119 article-title: Altered levels of the synaptosomal associated protein SNAP-25 in schizophrenia publication-title: Biological Psychiatry doi: 10.1016/S0006-3223(97)00204-7 – volume: 18 start-page: 121 year: 2000 ident: 10.1016/j.brainresrev.2006.09.001_bib108 article-title: Developmental maturation of the N-methyl-aspartic acid receptor channel complex in postnatal rat brain publication-title: International Journal of Developmental Neuroscience doi: 10.1016/S0736-5748(99)00069-6 – volume: 17 start-page: 319 year: 1982 ident: 10.1016/j.brainresrev.2006.09.001_bib36 article-title: Schizophrenia: caused by a fault in programmed synaptic elimination during adolescence? publication-title: Journal of Psychiatric Research doi: 10.1016/0022-3956(82)90038-3 – volume: 38 start-page: 92 year: 1995 ident: 10.1016/j.brainresrev.2006.09.001_bib99 article-title: Oligodendroglial development in human fetal cerebrum publication-title: Annals of Neurology doi: 10.1002/ana.410380116 – volume: 9 start-page: 11 year: 2004 ident: 10.1016/j.brainresrev.2006.09.001_bib118 article-title: Polymorphisms within 5′ end of the Neuregulin 1 gene are genetically associated with schizophrenia in the Chinese population publication-title: Molecular Psychiatry doi: 10.1038/sj.mp.4001436 – volume: 369 start-page: 145 year: 1999 ident: 10.1016/j.brainresrev.2006.09.001_bib38 article-title: Locomotion elicited by MK801 in developing and adult rats: temporal, environmental, and gender effects publication-title: European Journal of Pharmacology doi: 10.1016/S0014-2999(99)00070-9 – volume: 71 start-page: 877 year: 2002 ident: 10.1016/j.brainresrev.2006.09.001_bib113 article-title: Neuregulin 1 and susceptibility to schizophrenia publication-title: American Journal of Human Genetics doi: 10.1086/342734 – volume: 258 start-page: 1 year: 1998 ident: 10.1016/j.brainresrev.2006.09.001_bib122 article-title: Neuronal nitric oxide synthase is permanently decreased in the cerebellum of rats subjected to chronic neonatal blockade of N-methyl-d-aspartate receptors publication-title: Neuroscience Letters doi: 10.1016/S0304-3940(98)00742-3 – volume: 68 start-page: 818 year: 1961 ident: 10.1016/j.brainresrev.2006.09.001_bib68 article-title: Sex differences in adrenal cortical secretion in the rat publication-title: Endocrinology doi: 10.1210/endo-68-5-818 – volume: 40 start-page: 11 year: 2001 ident: 10.1016/j.brainresrev.2006.09.001_bib105 article-title: Neonatal phencyclidine treatment selectively attenuates mesolimbic dopamine function in adult rats as revealed by methamphetamine-induced behavior and c-fos mRNA expression in the brain publication-title: Synapse doi: 10.1002/1098-2396(200104)40:1<11::AID-SYN1021>3.0.CO;2-I – volume: 102 start-page: 414 year: 2000 ident: 10.1016/j.brainresrev.2006.09.001_bib3 article-title: Premorbid performance IQ deficit in schizophrenia publication-title: Acta Psychiatrica Scandinavica doi: 10.1034/j.1600-0447.2000.102006414.x – volume: 4 start-page: 133 year: 1983 ident: 10.1016/j.brainresrev.2006.09.001_bib12 article-title: The pituitary–adrenal response to novel stimulation and ether stress in young adult and aged rats publication-title: Neurobiology of Aging doi: 10.1016/0197-4580(83)90037-4 – volume: 620 start-page: 167 year: 1993 ident: 10.1016/j.brainresrev.2006.09.001_bib55 article-title: Sex differences in NMDA receptor mediated responses in rats publication-title: Brain Research doi: 10.1016/0006-8993(93)90287-W – volume: 9 start-page: 1693 year: 1989 ident: 10.1016/j.brainresrev.2006.09.001_bib58 article-title: Hypobaric–ischemic conditions produce glutamate-like cytopathology in infant rat brain publication-title: Journal of Neuroscience doi: 10.1523/JNEUROSCI.09-05-01693.1989 – volume: 368 start-page: 335 year: 1994 ident: 10.1016/j.brainresrev.2006.09.001_bib35 article-title: NMDA-receptor channel diversity in the developing cerebellum publication-title: Nature doi: 10.1038/368335a0 – volume: 27 start-page: 867 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib132 article-title: Pharmacological challenge reveals long-term effects of perinatal phencyclidine on delayed spatial alternation in rats publication-title: Progress in Neuro-Psychopharmacology and Biological Psychiatry doi: 10.1016/S0278-5846(03)00146-5 – volume: 153 start-page: 35 year: 1998 ident: 10.1016/j.brainresrev.2006.09.001_bib78 article-title: Evidence for synaptic apoptosis publication-title: Experimental Neurology doi: 10.1006/exnr.1998.6863 – volume: 254 start-page: 1515 year: 1991 ident: 10.1016/j.brainresrev.2006.09.001_bib90 article-title: NMDA antagonist neurotoxicity: mechanism and prevention publication-title: Science doi: 10.1126/science.1835799 – volume: 122 start-page: 593 year: 1999 ident: 10.1016/j.brainresrev.2006.09.001_bib51 article-title: The neuropathology of schizophrenia. A critical review of the data and their interpretation publication-title: Brain doi: 10.1093/brain/122.4.593 – volume: 87 start-page: 431 year: 1991 ident: 10.1016/j.brainresrev.2006.09.001_bib65 article-title: Prospective observations of 100 high-risk neonates by high-field (1.5 Telsa) magnetic resonance imaging of the central nervous system: II. Lesions associated with hypoxic-Ischemic encephalopathy publication-title: Pediatrics doi: 10.1542/peds.87.4.431 – volume: 98 start-page: 427 year: 1999 ident: 10.1016/j.brainresrev.2006.09.001_bib82 article-title: Mice with reduced NMDA receptor expression display behaviors related to schizophrenia publication-title: Cell doi: 10.1016/S0092-8674(00)81972-8 – volume: 8 start-page: 639 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib115 article-title: Neuregulin 1 in schizophrenia: out of Iceland publication-title: Molecular Psychiatry doi: 10.1038/sj.mp.4001384 – volume: 11 start-page: 613 year: 2006 ident: 10.1016/j.brainresrev.2006.09.001_bib84 article-title: Association of the NRG1 gene and schizophrenia: a meta-analysis publication-title: Molecular Psychiatry doi: 10.1038/sj.mp.4001840 – volume: 127 start-page: 123 year: 2001 ident: 10.1016/j.brainresrev.2006.09.001_bib98 article-title: Ontogeny of ionotropic glutamate receptor expression in human fetal brain publication-title: Developmental Brain Research doi: 10.1016/S0165-3806(01)00126-2 – volume: 26 start-page: 367 year: 2000 ident: 10.1016/j.brainresrev.2006.09.001_bib100 article-title: Childhood neuromotor dysfunction in schizophrenia patients and their unaffected siblings: a prospective cohort study publication-title: Schizophrenia Bulletin doi: 10.1093/oxfordjournals.schbul.a033459 – volume: 18 start-page: 1706 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib50 article-title: Long-term behavioural, molecular and morphological effects of neonatal NMDA receptor antagonism publication-title: European Journal of Neuroscience doi: 10.1046/j.1460-9568.2003.02902.x – volume: 62 start-page: 955 year: 1997 ident: 10.1016/j.brainresrev.2006.09.001_bib13 article-title: Altered NMDA sensitivity and learning following chronic developmental NMDA antagonism publication-title: Physiology and Behavior doi: 10.1016/S0031-9384(97)00169-8 – volume: 25 start-page: 4974 year: 2005 ident: 10.1016/j.brainresrev.2006.09.001_bib48 article-title: Regulation of NMDA receptors by neuregulin signaling in prefrontal cortex publication-title: Journal of Neuroscience doi: 10.1523/JNEUROSCI.1086-05.2005 – volume: 361 start-page: 417 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib52 article-title: Genes for schizophrenia? Recent findings and their pathophysiological implications publication-title: Lancet doi: 10.1016/S0140-6736(03)12379-3 – volume: 18 start-page: 5545 year: 1998 ident: 10.1016/j.brainresrev.2006.09.001_bib1 article-title: Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine publication-title: Journal of Neuroscience doi: 10.1523/JNEUROSCI.18-14-05545.1998 – volume: 33 start-page: 179 year: 1998 ident: 10.1016/j.brainresrev.2006.09.001_bib17 article-title: Differences in distribution of ages of onset in males and females with schizophrenia publication-title: Schizophrenia Research doi: 10.1016/S0920-9964(98)00070-X – volume: 304 start-page: 266 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib126 article-title: Blockade of phencyclidine-induced cortical apoptosis and deficits in prepulse inhibition by M40403, a superoxide dismutase mimetic publication-title: The Journal of Pharmacology and Experimental Therapeutics doi: 10.1124/jpet.102.041798 – volume: 52 start-page: 805 year: 1995 ident: 10.1016/j.brainresrev.2006.09.001_bib104 article-title: Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17 publication-title: Archives of General Psychiatry doi: 10.1001/archpsyc.1995.03950220015005 – volume: 111 start-page: 49 year: 1997 ident: 10.1016/j.brainresrev.2006.09.001_bib47 article-title: Early NMDA receptor blockade impairs defensive behavior and increases cell proliferation in the dentate gyrus of developing rats publication-title: Behavioral Neuroscience doi: 10.1037/0735-7044.111.1.49 – volume: 23 start-page: 876 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib64 article-title: Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits publication-title: Journal of Neuroscience doi: 10.1523/JNEUROSCI.23-03-00876.2003 – volume: 18 start-page: 1197 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib73 article-title: Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation publication-title: European Journal of Neuroscience doi: 10.1046/j.1460-9568.2003.02850.x – volume: 157 start-page: 1141 year: 2000 ident: 10.1016/j.brainresrev.2006.09.001_bib40 article-title: Ionotropic glutamate receptors and expression of N-methyl-d-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia publication-title: American Journal of Psychiatry doi: 10.1176/appi.ajp.157.7.1141 – volume: 48 start-page: 515 year: 2006 ident: 10.1016/j.brainresrev.2006.09.001_bib14 article-title: Neonatal administration of N-acetyl-l-aspartyl-l-glutamate induces early neurodegeneration in hippocampus and alters behaviour in young adult rats publication-title: Neurochemistry International doi: 10.1016/j.neuint.2006.01.019 – volume: 264 start-page: 705 year: 1976 ident: 10.1016/j.brainresrev.2006.09.001_bib19 article-title: Selective stabilisation of developing synapses as a mechanism for the specification of neuronal networks publication-title: Nature doi: 10.1038/264705a0 – volume: 25 start-page: 9378 year: 2005 ident: 10.1016/j.brainresrev.2006.09.001_bib70 article-title: Neuregulin-1 reverses long-term potentiation at CA1 hippocampal synapses publication-title: Journal of Neuroscience doi: 10.1523/JNEUROSCI.2100-05.2005 – volume: 110 start-page: 309 year: 2002 ident: 10.1016/j.brainresrev.2006.09.001_bib16 article-title: Interaction between neuropeptide FF and opioids in the ventral tegmental area in the behavioral response to novelty publication-title: Neuroscience doi: 10.1016/S0306-4522(01)00587-5 – volume: 153 start-page: 367 year: 2004 ident: 10.1016/j.brainresrev.2006.09.001_bib39 article-title: Neurofunctional deficits and potentiated apoptosis by neonatal NMDA antagonist administration publication-title: Behavioural Brain Research doi: 10.1016/j.bbr.2003.12.026 – volume: 69 start-page: 339 year: 1995 ident: 10.1016/j.brainresrev.2006.09.001_bib27 article-title: Decreased synaptophysin in the medial temporal lobe in schizophrenia demonstrated using immunoautoradiography publication-title: Neuroscience doi: 10.1016/0306-4522(95)00324-C – volume: 99 start-page: 126 year: 1997 ident: 10.1016/j.brainresrev.2006.09.001_bib128 article-title: Modulatory treatment of NMDA receptors in neonatal rats affects cognitive behavior in adult age publication-title: Developmental Brain Research doi: 10.1016/S0165-3806(96)00204-0 – volume: 20 start-page: 154 year: 1998 ident: 10.1016/j.brainresrev.2006.09.001_bib22 article-title: Postnatal development of glutamate receptor-mediated responses in the neostriatum publication-title: Developmental Neuroscience doi: 10.1159/000017310 – volume: 166 start-page: 386 year: 1969 ident: 10.1016/j.brainresrev.2006.09.001_bib89 article-title: Brain lesions in an infant rhesus monkey treated with nonsodium glutamate publication-title: Science doi: 10.1126/science.166.3903.386 – volume: 37 start-page: 167 year: 2000 ident: 10.1016/j.brainresrev.2006.09.001_bib6 article-title: Dopamine receptor pruning in prefrontal cortex during the periadolescent period in rats publication-title: Synapse doi: 10.1002/1098-2396(200008)37:2<167::AID-SYN11>3.0.CO;2-B – volume: 161 start-page: 742 year: 2004 ident: 10.1016/j.brainresrev.2006.09.001_bib9 article-title: Pathology of layer V pyramidal neurons in the prefrontal cortex of patients with schizophrenia publication-title: American Journal of Psychiatry doi: 10.1176/appi.ajp.161.4.742 – volume: 19 start-page: 519 year: 1997 ident: 10.1016/j.brainresrev.2006.09.001_bib123 article-title: Brain injury in the premature infant—From pathogenesis to prevention publication-title: Brain Development doi: 10.1016/S0387-7604(97)00078-8 – volume: 75 start-page: 389 year: 2005 ident: 10.1016/j.brainresrev.2006.09.001_bib2 article-title: Differential patterns of premorbid academic and social deterioration in patients with schizophrenia publication-title: Schizophrenia Research doi: 10.1016/j.schres.2004.11.011 – volume: 27 start-page: 73 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib20 article-title: Early disruption of the mother-infant relationship: effects on brain plasticity and implications for psychopathology publication-title: Neuroscience and Biobehavioral Reviews doi: 10.1016/S0149-7634(03)00010-1 – volume: 159 start-page: 244 year: 2002 ident: 10.1016/j.brainresrev.2006.09.001_bib56 article-title: Volume changes in gray matter in patients with schizophrenia publication-title: American Journal of Psychiatry doi: 10.1176/appi.ajp.159.2.244 – volume: 29 start-page: 846 year: 2005 ident: 10.1016/j.brainresrev.2006.09.001_bib62 article-title: Apoptotic mechanisms in the pathophysiology of schizophrenia publication-title: Progress in Neuro-Psychopharmacology and Biological Psychiatry doi: 10.1016/j.pnpbp.2005.03.010 – volume: 12 start-page: 347 year: 1995 ident: 10.1016/j.brainresrev.2006.09.001_bib32 article-title: alpha 2 adrenergic agonists prevent MK-801 neurotoxicity publication-title: Neuropsychopharmacology doi: 10.1016/0893-133X(95)00048-I – volume: 72 start-page: 83 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib114 article-title: Association of neuregulin 1 with schizophrenia confirmed in a Scottish population publication-title: American Journal of Human Genetics doi: 10.1086/345442 – volume: 8 start-page: 485 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib133 article-title: Support for genetic variation in neuregulin 1 and susceptibility to schizophrenia publication-title: Molecular Psychiatry doi: 10.1038/sj.mp.4001348 – volume: 122 start-page: 91 year: 2000 ident: 10.1016/j.brainresrev.2006.09.001_bib61 article-title: Maturation of locomotor and Fos responses to the NMDA antagonists, PCP and MK-801 publication-title: Developmental Brain Research doi: 10.1016/S0165-3806(00)00059-6 – volume: 260 start-page: 95 year: 1993 ident: 10.1016/j.brainresrev.2006.09.001_bib69 article-title: Modulation of neuronal migration by NMDA receptors publication-title: Science doi: 10.1126/science.8096653 – volume: 54 start-page: 17 year: 2002 ident: 10.1016/j.brainresrev.2006.09.001_bib124 article-title: Pubertal neurodevelopment and the emergence of psychotic symptoms publication-title: Schizophrenia Research doi: 10.1016/S0920-9964(01)00347-4 – volume: 665 start-page: 63 year: 1994 ident: 10.1016/j.brainresrev.2006.09.001_bib44 article-title: NMDA receptor responses in adult hippocampal CA1 region after neonatal treatment with MK-801: comparison with NMDA receptor responses in the immature rat publication-title: Brain Research doi: 10.1016/0006-8993(94)91152-5 – volume: 3 start-page: 79 year: 1979 ident: 10.1016/j.brainresrev.2006.09.001_bib26 article-title: Comparative aspects of the brain growth spurt publication-title: Early Human Development doi: 10.1016/0378-3782(79)90022-7 – volume: 39 start-page: 359 year: 1996 ident: 10.1016/j.brainresrev.2006.09.001_bib106 article-title: Effects of sigma ligands on the ability of rimcazole to inhibit PCP hsp70 induction publication-title: Brain Research Bulletin doi: 10.1016/0361-9230(96)00003-2 – volume: 696 start-page: 194 year: 1995 ident: 10.1016/j.brainresrev.2006.09.001_bib37 article-title: Quantitative analysis of factors influencing neuronal necrosis induced by MK-801 in the rat posterior cingulate/retrosplenial cortex publication-title: Brain Research doi: 10.1016/0006-8993(95)00842-E – volume: 27 start-page: 355 year: 1995 ident: 10.1016/j.brainresrev.2006.09.001_bib120 article-title: Treatment with NMDA receptor antagonists does not affect developmental changes in NMDA receptor properties in vivo publication-title: Neurochemistry International doi: 10.1016/0197-0186(95)00017-3 – volume: 66 start-page: 1240 year: 1996 ident: 10.1016/j.brainresrev.2006.09.001_bib130 article-title: Developmental and regional expression of NMDA receptor subtypes containing the NR2D subunit in rat brain publication-title: Journal of Neurochemistry doi: 10.1046/j.1471-4159.1996.66031240.x – volume: 480 start-page: 177 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib21 article-title: The genetics of schizophrenia: glutamate not dopamine? publication-title: European Journal of Pharmacology doi: 10.1016/j.ejphar.2003.08.105 – volume: 148 start-page: 1301 year: 1991 ident: 10.1016/j.brainresrev.2006.09.001_bib63 article-title: Recent advances in the phencyclidine model of schizophrenia publication-title: American Journal of Psychiatry doi: 10.1176/ajp.148.10.1301 – volume: 390 start-page: 691 year: 1997 ident: 10.1016/j.brainresrev.2006.09.001_bib93 article-title: Neuregulin-beta induces expression of an NMDA-receptor subunit publication-title: Nature doi: 10.1038/37795 – volume: 97 start-page: 217 year: 1984 ident: 10.1016/j.brainresrev.2006.09.001_bib85 article-title: Sex-dependent differences in the pharmacological actions and pharmacokinetics of phencyclidine in rats publication-title: European Journal of Pharmacology doi: 10.1016/0014-2999(84)90453-9 – volume: 15 start-page: 339 year: 1978 ident: 10.1016/j.brainresrev.2006.09.001_bib11 article-title: Prestimulus effects on human startle reflex in normals and schizophrenics publication-title: Psychophysiology doi: 10.1111/j.1469-8986.1978.tb01390.x – volume: 580 start-page: 12 year: 1992 ident: 10.1016/j.brainresrev.2006.09.001_bib45 article-title: Chronic neonatal MK-801 treatment results in an impairment of spatial learning in the adult rat publication-title: Brain Research doi: 10.1016/0006-8993(92)90921-U – volume: 3 start-page: 279 year: 1980 ident: 10.1016/j.brainresrev.2006.09.001_bib71 article-title: The Generation of Neuromuscular Specificity publication-title: Annual Review of Neuroscience doi: 10.1146/annurev.ne.03.030180.001431 – volume: 45 start-page: 17 year: 1999 ident: 10.1016/j.brainresrev.2006.09.001_bib103 article-title: The reduced neuropil hypothesis: a circuit based model of schizophrenia publication-title: Biological Psychiatry doi: 10.1016/S0006-3223(98)00281-9 – volume: 27 start-page: 787 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib72 article-title: Chronic neonatal N-methyl-aspartate receptor blockade induces learning deficits and transient hypoactivity in young rats publication-title: Progress in Neuro-Psychopharmacology and Biological Psychiatry doi: 10.1016/S0278-5846(03)00110-6 – volume: 74 start-page: 979 year: 2000 ident: 10.1016/j.brainresrev.2006.09.001_bib121 article-title: ErbB-4 activation promotes neurite outgrowth in PC12 cells publication-title: Journal of Neurochemistry doi: 10.1046/j.1471-4159.2000.0740979.x – volume: 63 start-page: 451 year: 1994 ident: 10.1016/j.brainresrev.2006.09.001_bib24 article-title: Chronic neonatal blockade of N-methyl-d-aspartate receptor by CGP 39551 increases dopaminergic function in adult rat publication-title: Neuroscience doi: 10.1016/0306-4522(94)90542-8 – volume: 16 start-page: 440 year: 2004 ident: 10.1016/j.brainresrev.2006.09.001_bib49 article-title: Mechanisms leading to disseminated apoptosis following NMDA receptor blockade in the developing rat brain publication-title: Neurobiology of Disease doi: 10.1016/j.nbd.2004.03.013 – volume: 36 start-page: 62 year: 2004 ident: 10.1016/j.brainresrev.2006.09.001_bib116 article-title: Neuregulin 1 and schizophrenia publication-title: Annals of Medicine doi: 10.1080/07853890310017585 – volume: 34 start-page: 119 year: 1993 ident: 10.1016/j.brainresrev.2006.09.001_bib31 article-title: Antipsychotic drugs block phencyclidine receptor-mediated neurotoxicity publication-title: Biological Psychiatry doi: 10.1016/0006-3223(93)90265-F – volume: 74 start-page: 219 year: 1993 ident: 10.1016/j.brainresrev.2006.09.001_bib29 article-title: Structural, neurochemical and behavioural consequences of neonatal blockade of NMDA receptor through chronic treatment with CGP 39551 or MK-801 publication-title: Developmental Brain Research doi: 10.1016/0165-3806(93)90007-W – volume: 55 start-page: 43 issue: Suppl B year: 1994 ident: 10.1016/j.brainresrev.2006.09.001_bib88 article-title: Efficacy of clozapine compared with other antipsychotics in preventing NMDA-antagonist neurotoxicity publication-title: Journal of Clinical Psychiatry – volume: 74 start-page: 129 year: 1997 ident: 10.1016/j.brainresrev.2006.09.001_bib25 article-title: Schizophrenia as a chronic active brain process: a study of progressive brain structural change subsequent to the onset of schizophrenia publication-title: Psychiatry Research doi: 10.1016/S0925-4927(97)00012-7 – volume: 8 start-page: 1495 year: 1997 ident: 10.1016/j.brainresrev.2006.09.001_bib5 article-title: Sex differences in dopamine receptor overproduction and elimination publication-title: NeuroReport doi: 10.1097/00001756-199704140-00034 – volume: 109 start-page: 211 year: 1998 ident: 10.1016/j.brainresrev.2006.09.001_bib134 article-title: Expression of NMDA receptor subunit mRNA after MK-801 treatment in neonatal rats publication-title: Developmental Brain Research doi: 10.1016/S0165-3806(98)00084-4 – volume: 159 start-page: 124 year: 1999 ident: 10.1016/j.brainresrev.2006.09.001_bib57 article-title: N-methyl-aspartate receptor blockade induces neuronal apoptosis in cortical culture publication-title: Experimental Neurology doi: 10.1006/exnr.1999.7126 – volume: 27 start-page: 3 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib4 article-title: Trajectories of brain development: point of vulnerability or window of opportunity? publication-title: Neuroscience and Biobehavioral Reviews doi: 10.1016/S0149-7634(03)00005-8 – volume: 12 start-page: 3117 year: 2000 ident: 10.1016/j.brainresrev.2006.09.001_bib83 article-title: Blockade of the NMDA receptor increases developmental apoptotic elimination of granule neurons and activates caspases in the rat cerebellum publication-title: European Journal of Neuroscience doi: 10.1046/j.1460-9568.2000.00189.x – volume: 40 start-page: 881 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib81 article-title: Bringing order to the glutamate chaos in schizophrenia publication-title: Neuron doi: 10.1016/S0896-6273(03)00757-8 – volume: 44 start-page: 660 year: 1987 ident: 10.1016/j.brainresrev.2006.09.001_bib129 article-title: Implications of normal brain development for the pathogenesis of schizophrenia publication-title: Archives of General Psychiatry doi: 10.1001/archpsyc.1987.01800190080012 – volume: 2 start-page: 861 year: 1999 ident: 10.1016/j.brainresrev.2006.09.001_bib41 article-title: Brain development during childhood and adolescence: a longitudinal MRI study publication-title: Nature Neuroscience doi: 10.1038/13158 – volume: 5 start-page: 2688 year: 1994 ident: 10.1016/j.brainresrev.2006.09.001_bib28 article-title: Competitive and non-competitive NMDA antagonists induce similar limbic degeneration publication-title: NeuroReport doi: 10.1097/00001756-199412000-00070 – volume: 14 start-page: 1358 year: 1994 ident: 10.1016/j.brainresrev.2006.09.001_bib42 article-title: NMDA receptor antagonists decrease GABA outflow from the septum and increase acetylcholine outflow from the hippocampus: a microdialysis study publication-title: Journal of Neuroscience doi: 10.1523/JNEUROSCI.14-03-01358.1994 – volume: 57 start-page: 433 year: 2005 ident: 10.1016/j.brainresrev.2006.09.001_bib112 article-title: Transient N-methyl-d-aspartate receptor blockade in early development causes lasting cognitive deficits relevant to schizophrenia publication-title: Biological Psychiatry doi: 10.1016/j.biopsych.2004.11.031 – volume: 25 start-page: 1362 year: 1994 ident: 10.1016/j.brainresrev.2006.09.001_bib77 article-title: Activity-dependent and hormonal regulation of neurotrophin mRNA levels in the brain—Implications for neuronal plasticity publication-title: Journal of Neurobiology doi: 10.1002/neu.480251105 – volume: 108 start-page: 383 issue: Suppl. 3 year: 2000 ident: 10.1016/j.brainresrev.2006.09.001_bib92 article-title: Environmental agents that have the potential to trigger massive apoptotic neurodegeneration in the developing brain publication-title: Environmental Health Perspectives doi: 10.2307/3454524 – volume: 59 start-page: 612 year: 2000 ident: 10.1016/j.brainresrev.2006.09.001_bib94 article-title: Roles of neuregulin in synaptogenesis between mossy fibers and cerebellar granule cells publication-title: Journal of Neuroscience Research doi: 10.1002/(SICI)1097-4547(20000301)59:5<612::AID-JNR4>3.0.CO;2-V – volume: 164 start-page: 719 year: 1969 ident: 10.1016/j.brainresrev.2006.09.001_bib86 article-title: Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate publication-title: Science doi: 10.1126/science.164.3880.719 – volume: 95 start-page: 256 year: 1996 ident: 10.1016/j.brainresrev.2006.09.001_bib117 article-title: Long-term effects of excitatory amino acid antagonists NBQX and MK-801 on the developing brain publication-title: Developmental Brain Research doi: 10.1016/0165-3806(96)00094-6 – volume: 40 start-page: 214 year: 1996 ident: 10.1016/j.brainresrev.2006.09.001_bib111 article-title: Postnatal phencyclidine treatment differentially regulates N-methyl-aspartate receptor subunit mRNA expression in developing rat cerebral cortex publication-title: Molecular Brain Research doi: 10.1016/0169-328X(96)00051-4 – volume: 26 start-page: 183 year: 1995 ident: 10.1016/j.brainresrev.2006.09.001_bib101 article-title: Hypoxic ischaemic encephalopathy: early magnetc resonance imaging findings and their evolution publication-title: Neuropediatrics doi: 10.1055/s-2007-979751 – volume: 15 start-page: 1995 year: 2006 ident: 10.1016/j.brainresrev.2006.09.001_bib75 article-title: Meta-analysis shows strong positive association of the neuregulin 1 (NRG1) gene with schizophrenia publication-title: Human Molecular Genetics doi: 10.1093/hmg/ddl122 – year: 2007 ident: 10.1016/j.brainresrev.2006.09.001_bib7 – volume: 33 start-page: 523 year: 1999 ident: 10.1016/j.brainresrev.2006.09.001_bib91 article-title: NMDA receptor hypofunction model of schizophrenia publication-title: Journal of Psychiatric Research doi: 10.1016/S0022-3956(99)00029-1 – volume: 137 start-page: 97 year: 1992 ident: 10.1016/j.brainresrev.2006.09.001_bib46 article-title: Chronic neonatal NMDA receptor blockade with MK-801 alters monoamine metabolism in the adult rat publication-title: Neuroscience Letters doi: 10.1016/0304-3940(92)90307-S – volume: 223 start-page: 143 year: 1987 ident: 10.1016/j.brainresrev.2006.09.001_bib96 article-title: Glutamate acting on NMDA receptors stimulates neurite outgrowth from cerebellar granule cells publication-title: FEBS Letters doi: 10.1016/0014-5793(87)80525-2 – volume: 100 start-page: 4251 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib102 article-title: Neuregulin 1-erbB2 signaling is required for the establishment of radial glia and their transformation into astrocytes in cerebral cortex publication-title: PNAS doi: 10.1073/pnas.0630496100 – volume: 12 start-page: 15 year: 1990 ident: 10.1016/j.brainresrev.2006.09.001_bib80 article-title: Neonatal ethanol exposure: functional alterations associated with cerebellar growth retardation publication-title: Neurotoxicology and Teratology doi: 10.1016/0892-0362(90)90107-N – volume: 68 start-page: 469 year: 1997 ident: 10.1016/j.brainresrev.2006.09.001_bib131 article-title: NMDA receptor heterogeneity during postnatal development of the rat brain: differential expression of the NR2A, NR2B, and NR2C subunit proteins publication-title: Journal of Neurochemistry doi: 10.1046/j.1471-4159.1997.68020469.x – volume: 357 start-page: 686 year: 1992 ident: 10.1016/j.brainresrev.2006.09.001_bib53 article-title: Developmental regulation of NMDA receptor-mediated synaptic currents at a central synapse publication-title: Nature doi: 10.1038/357686a0 – volume: 23 start-page: 659 year: 2002 ident: 10.1016/j.brainresrev.2006.09.001_bib87 article-title: New insights and new issues in developmental neurotoxicology publication-title: NeuroToxicology doi: 10.1016/S0161-813X(01)00092-4 – volume: 21 start-page: 159 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib109 article-title: Postnatal phencyclidine-induced deficit in adult water maze performance is associated with N-methyl-aspartate receptor upregulation publication-title: International Journal of Developmental Neuroscience doi: 10.1016/S0736-5748(03)00026-1 – volume: 118 start-page: 284 year: 1992 ident: 10.1016/j.brainresrev.2006.09.001_bib74 article-title: Density and distribution of excitatory amino acid receptors in the developing human fetal brain: a quantitative autoradiographic study publication-title: Experimental Neurology doi: 10.1016/0014-4886(92)90185-S – volume: 6 start-page: 427 year: 1996 ident: 10.1016/j.brainresrev.2006.09.001_bib15 article-title: Programmed cell death in the developing nervous system publication-title: Brain Pathology doi: 10.1111/j.1750-3639.1996.tb00874.x – volume: 88 start-page: 10218 year: 1991 ident: 10.1016/j.brainresrev.2006.09.001_bib76 article-title: Synchronized overproduction of neurotransmitter receptors in diverse regions of the primate cerebral cortex publication-title: Proceedings of the National Academy of Sciences of the United States of America doi: 10.1073/pnas.88.22.10218 – volume: 125 start-page: 473 year: 2004 ident: 10.1016/j.brainresrev.2006.09.001_bib127 article-title: Blockade of N-methyl-aspartate receptors by phencyclidine causes the loss of corticostriatal neurons publication-title: Neuroscience doi: 10.1016/j.neuroscience.2004.02.003 – volume: 20 start-page: 379 year: 1980 ident: 10.1016/j.brainresrev.2006.09.001_bib67 article-title: Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia publication-title: Neuroscience Letters doi: 10.1016/0304-3940(80)90178-0 – volume: 31 start-page: 251 year: 2000 ident: 10.1016/j.brainresrev.2006.09.001_bib8 article-title: Emerging principles of altered neural circuitry in schizophrenia publication-title: Brain Research Reviews doi: 10.1016/S0165-0173(99)00041-7 – volume: 60 start-page: 343 year: 1994 ident: 10.1016/j.brainresrev.2006.09.001_bib30 article-title: Long-lasting effects of chronic neonatal blockade of N-methyl-d-aspartate receptor through the competitive antagonist CGP 39551 in rats publication-title: Neuroscience doi: 10.1016/0306-4522(94)90248-8 – volume: 56 start-page: 649 year: 1999 ident: 10.1016/j.brainresrev.2006.09.001_bib97 article-title: Progressive cortical change during adolescence in childhood-onset schizophrenia. A longitudinal magnetic resonance imaging study publication-title: Archives of General Psychiatry doi: 10.1001/archpsyc.56.7.649 – volume: 15 start-page: 477 year: 1989 ident: 10.1016/j.brainresrev.2006.09.001_bib54 article-title: Cortical pruning and the development of schizophrenia: a computer model publication-title: Schizophrenia Bulletin doi: 10.1093/schbul/15.3.477 – volume: 74 start-page: 943 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib110 article-title: Effects of postnatal PCP treatment on locomotor behavior and striatal D2 receptor publication-title: Pharmacology Biochemistry and Behavior doi: 10.1016/S0091-3057(03)00025-X – volume: 8 start-page: 706 year: 2003 ident: 10.1016/j.brainresrev.2006.09.001_bib136 article-title: Association study of neuregulin 1 gene with schizophrenia publication-title: Molecular Psychiatry doi: 10.1038/sj.mp.4001377 – volume: 28 start-page: 239 year: 1994 ident: 10.1016/j.brainresrev.2006.09.001_bib66 article-title: Is Schizophrenia due to excessive synaptic pruning in the prefrontal cortex? The Feinberg hypothesis revisited publication-title: Journal of Psychiatric Research doi: 10.1016/0022-3956(94)90009-4 – volume: 57 start-page: 637 year: 2000 ident: 10.1016/j.brainresrev.2006.09.001_bib79 article-title: Schizophrenia as a disorder of developmentally reduced synaptic connectivity publication-title: Archives of General Psychiatry doi: 10.1001/archpsyc.57.7.637 – volume: 33 start-page: 605 year: 1992 ident: 10.1016/j.brainresrev.2006.09.001_bib107 article-title: Haloperidol prevents induction of the hsp70 heat shock gene in neurons injured by phencyclidine (PCP), MK801, and ketamine publication-title: Journal of Neuroscience Research doi: 10.1002/jnr.490330413 – volume: 38 start-page: 788 year: 1995 ident: 10.1016/j.brainresrev.2006.09.001_bib33 article-title: Age-specific neurotoxicity in the rat associated with NMDA receptor blockade: potential relevance to schizophrenia? publication-title: Biological Psychiatry doi: 10.1016/0006-3223(95)00046-1 |
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| Snippet | Abstract Disruption to brain development at an early stage can potentially alter chemically coded neural networks and can affect behavior in later life. During... Disruption to brain development at an early stage can potentially alter chemically coded neural networks and can affect behavior in later life. During early... |
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| SubjectTerms | Adult and adolescent clinical studies Animals Biological and medical sciences Brain - embryology Brain - growth & development Brain - metabolism Brain development Humans Medical sciences Neurology NMDA receptor hypofunction Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Receptors, N-Methyl-D-Aspartate - physiology Schizophrenia Schizophrenia - metabolism Schizophrenia - pathology |
| Title | Early brain development disruption from NMDA receptor hypofunction: Relevance to schizophrenia |
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