Plasma Metabolomics Profiling in Maintenance Hemodialysis Patients Based on Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry

• Published in: Kidney diseases Vol. 6; no. 2; pp. 125 - 134
• Main Authors: Chen, Yu, Wen, Ping, Yang, Junwei, Niu, Jianying
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 01.03.2020
• Subjects: Analysis; Chronic kidney failure; Development and progression; Ethylenediaminetetraacetic acid; Hemodialysis; Liquid chromatography; Metabolites; Organic acids; Research Article; Spectrum analysis; Type 2 diabetes; China; Metabolic profiling; Liquid chromatography quadrupole time-of-flight mass spectrometry; End-stage renal disease

Background: Key pathogenetic mechanisms underlying renal disease progression are unaffected by current treatment. Metabolite profiling has significantly contributed to a deeper understanding of the biochemical metabolic networks and pathways in disease, but the biochemical details in maintenance hem...