Ethnicity, sex, FADS genetic variation, and hormonal contraceptive use influence delta-5- and delta-6-desaturase indices and plasma docosahexaenoic acid concentration in young Canadian adults: a cross-sectional study

• Published in: Nutrition & metabolism Vol. 12; no. 1; p. 14
• Main Authors: Abdelmagid, Salma A, Clarke, Shannon E, Roke, Kaitlin, Nielsen, Daiva E, Badawi, Alaa, El-Sohemy, Ahmed, Mutch, David M, Ma, David WL
• Format: Journal Article
• Language: English
• Published: England Springer-Verlag 21.04.2015; BioMed Central Ltd; BioMed Central
• Subjects: adults; alpha-linolenic acid; Analysis; arachidonic acid; contraceptives; cross-sectional studies; docosahexaenoic acid; eicosapentaenoic acid; Essential fatty acids; fasting; fatty acid composition; females; gas chromatography; Genetic aspects; Genetic polymorphisms; genetic variation; linoleic acid; males; nutrigenomics; Oral contraceptives; Physiological aspects; single nucleotide polymorphism; Unsaturated fatty acids; Whites; Ontario

BACKGROUND: There is great interest in the relationship between polyunsaturated fatty acids and health. Yet, the combinatory effect of factors such as sex, ethnicity, genetic polymorphisms and hormonal contraceptives (HC) on the concentrations of these fatty acids is unknown. Therefore, we sought to...