Atypical Neural Processing of Ironic and Sincere Remarks in Children and Adolescents with Autism Spectrum Disorders

• Published in: Metaphor and symbol Vol. 27; no. 1; pp. 70 - 92
• Main Authors: Colich, Natalie L., Wang, Audrey-Ting, Rudie, Jeffrey D., Hernandez, Leanna M., Bookheimer, Susan Y., Dapretto, Mirella
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis Group 01.01.2012; Taylor & Francis Ltd
• Subjects: Adolescence; Autism; Behavior; Brain; Children; Children & youth; Cognition; Cortex (prefrontal); Functional magnetic resonance imaging; Hemispheric laterality; Information processing; Language; Nodes; Social interaction; Social interactions

Individuals with ASD show consistent impairment in processing pragmatic language when attention to multiple social cues (e.g., facial expression, tone of voice) is often needed to navigate social interactions. Building upon prior fMRI work examining how facial affect and prosodic cues are used to in...