Correlation between clinical indicators of lead poisoning and oxidative stress parameters in controls and lead-exposed workers

• Published in: Toxicology (Amsterdam) Vol. 195; no. 2; pp. 147 - 154
• Main Authors: Gurer-Orhan, Hande, Sabir, Handan U, Ozgunes, Hilal
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 15.02.2004; Amsterdam Elsevier Science
• Subjects: Adult; Biological and medical sciences; Catalase - blood; Chemical and industrial products toxicology. Toxic occupational diseases; Erythrocytes - drug effects; Erythrocytes - metabolism; Glucosephosphate Dehydrogenase - blood; Glutathione - blood; Humans; Lead - blood; Lead poisoning; Lead Poisoning - metabolism; Male; Malondialdehyde - blood; Medical sciences; Metals and various inorganic compounds; Occupational Diseases; Occupational Exposure; Oxidative Stress; Porphobilinogen Synthase - blood; Protoporphyrins - blood; Toxicology; Workers; δ-Aminolevulinic acid dehydratase; δ-Aminolevulinic acid dehydratase; Oxidative stress; Workers; Lead poisoning; Human; Porphobilinogen synthase; Enzyme; Biological marker; Lyases; Occupational exposure; Saturnism; Heavy metal; Lead; Worker; Carbon-oxygen lyases; Occupational medicine; Hydro-lyases

The present study was undertaken to investigate the involvement of oxidative damage in lead-induced toxicity in humans and to enlighten whether oxidative stress indicators are correlated with the known indices of lead toxicity. For these purposes, selected oxidative stress parameters along with some...