Post-stroke deficit prediction from lesion and indirect structural and functional disconnection

• Published in: Brain (London, England : 1878) Vol. 143; no. 7; pp. 2173 - 2188
• Main Authors: Salvalaggio, Alessandro, De Filippo De Grazia, Michele, Zorzi, Marco, Thiebaut de Schotten, Michel, Corbetta, Maurizio
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.07.2020
• Subjects: Adult; Aged; Brain - diagnostic imaging; Brain - physiopathology; Cognitive science; Connectome - methods; Female; Humans; Male; Middle Aged; Multimodal Imaging - methods; Nerve Net - diagnostic imaging; Nerve Net - physiopathology; Neuroimaging - methods; Original; Recovery of Function - physiology; Stroke - diagnostic imaging; Stroke - physiopathology; Young Adult; structural disconnection; connectivity; stroke; lesion; functional disconnection

Behavioural deficits in stroke reflect both structural damage at the site of injury, and widespread network dysfunction caused by structural, functional, and metabolic disconnection. Two recent methods allow for the estimation of structural and functional disconnection from clinical structural imagi...