Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species - Wang, Ruoke; Zhang, Qi; Ge, Jiwan; Ren, Wenlin; Zhang, Rui; Lan, Jun; Ju, Bin; Su, Bin; Yu, Fengting; Chen, Peng; Liao, Huiyu; Feng, Yingmei; et al. (Immunity (Cambridge, Mass.), 2021)
Keywords: ACE2; Angiotensin-converting enzyme 2; Angiotensin-Converting Enzyme 2 - metabolism; Animals; Antibodies; Antibodies, Monoclonal - chemistry; Antibodies, Monoclonal - immunology; Antibodies, Neutralizing - chemistry; Antibodies, Neutralizing - immunology; antibody; Antigenic Variation - genetics; Antigens; Coronaviruses; COVID-19; COVID-19 - immunology; COVID-19 - virology; COVID-19 vaccines; Crystal structure; Disease transmission; Domains; Host range; Host Specificity; Humans; immune escape; Immune Evasion - genetics; Immunotherapy; Infections; Mice; Mink; Monoclonal antibodies; Mutation; Neutralization; Pandemics; Protein Binding; Proteins; Receptors; RNA polymerase; SARS-CoV-2; SARS-CoV-2 - genetics; SARS-CoV-2 - immunology; SARS-CoV-2 - physiology; Severe acute respiratory syndrome; Severe acute respiratory syndrome coronavirus 2; Spike Glycoprotein, Coronavirus - chemistry; Spike Glycoprotein, Coronavirus - genetics; Spike Glycoprotein, Coronavirus - immunology; Spike Glycoprotein, Coronavirus - metabolism; Structural analysis; Vaccines; variant of concern; Viral diseases; Virus Internalization; United Kingdom--UK; England; variant of concern; SARS-CoV-2; immune escape; antibody; neutralization