Ghrelin ameliorates A549 cell apoptosis caused by paraquat via p38-MAPK regulated mitochondrial apoptotic pathway - Cui, Shuqing; Nian, Qing; Chen, Gang; Wang, Xingyong; Zhang, Jinying; Qiu, Jianqing; Zhang, Zhiqiang (Toxicology (Amsterdam), 2019)
Keywords: A549 Cells; acetylcysteine; Acute lung injury; antioxidants; Apoptosis; Apoptosis - drug effects; Caspase 3 - biosynthesis; Caspase 3 - drug effects; caspase-3; Cell Survival - drug effects; cell viability; Emergency; epithelial cells; Ghrelin; Ghrelin - pharmacology; Herbicides - toxicity; Humans; lipid peroxidation; lungs; MAP Kinase Signaling System - drug effects; membrane potential; Membrane Potential, Mitochondrial - drug effects; mitochondria; Mitochondria - drug effects; mitochondrial membrane; mitogen-activated protein kinase; mortality; oxidative stress; Oxidative Stress - drug effects; p38 Mitogen-Activated Protein Kinases - drug effects; p38 Mitogen-Activated Protein Kinases - metabolism; p38-MAPK; Paraquat; Paraquat - antagonists & inhibitors; Paraquat - toxicity; phosphorylation; Reactive Oxygen Species - metabolism; small interfering RNA; Acute lung injury; Paraquat; p38-MAPK; Ghrelin; Apoptosis