B-chronic lymphocytic leukemia cells and other B cells can produce granzyme B and gain cytotoxic potential after interleukin-21-based activation
B cells currently are not viewed as being capable of producing granzyme B or being cytotoxic. We found that B-chronic lymphocytic leukemia (B-CLL) cells treated with interleukin-21 (IL-21) produce low levels of granzyme B. The addition of either CpG oligodeoxynucleotide (ODN) or anti-B-cell-receptor...
Saved in:
Published in | Blood Vol. 108; no. 8; pp. 2712 - 2719 |
---|---|
Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Washington, DC
Elsevier Inc
15.10.2006
The Americain Society of Hematology 2006 by The American Society of Hematology |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Be the first to leave a comment!