Patients with both CYP2C19 loss-of-function allele and peripheral endothelial dysfunction are significantly correlated with adverse cardiovascular events following coronary stent implantation - Tabata, Noriaki; Hokimoto, Seiji; Akasaka, Tomonori; Arima, Yuichiro; Sakamoto, Kenji; Yamamoto, Eiichiro; Tsujita, Kenichi; Izumiya, Yasuhiro; Yamamuro, Megumi; Kojima, Sunao; Kaikita, Koichi; Kumagae, Naoki; et al. (Journal of cardiology, 2016)
Keywords: Aged; Angina, Unstable - epidemiology; Cardiovascular; Clopidogrel; CYP2C19; Cytochrome P-450 CYP2C19 - genetics; Endothelial dysfunction; Endothelium, Vascular - physiopathology; Female; Follow-Up Studies; Genotype; Heart Failure - epidemiology; Heterozygote; Humans; Japan - epidemiology; Male; Middle Aged; Myocardial Infarction - epidemiology; Myocardial Revascularization - statistics & numerical data; Percutaneous Coronary Intervention - adverse effects; Polymorphism, Genetic; Proportional Hazards Models; Prospective Studies; Stent; Stents; Stroke - epidemiology; Endothelial dysfunction; Clopidogrel; CYP2C19; Stent