Antagonistic effects of atipamezole and yohimbine on xylazine-induced diuresis in healthy dogs

• Published in: Journal of Veterinary Medical Science Vol. 71; no. 5; pp. 539 - 548
• Main Authors: Talukder, Md.h.(Tottori Univ. (Japan). Faculty of Agriculture), Hikasa, Y, Matsuu, A, Kawamura, H
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 01.05.2009; Japan Science and Technology Agency
• Subjects: Adrenergic alpha-Antagonists - pharmacology; Animals; ANTAGONISM; ANTAGONISME; ANTAGONISMO; arginine vasopressin; Arginine Vasopressin - blood; Arginine Vasopressin - urine; atipamezole; Atrial Natriuretic Factor - blood; Atrial Natriuretic Factor - urine; atrial natriuretic peptide; CHIEN; Chlorides - urine; Creatinine - urine; diuresis; Diuresis - drug effects; DOGS; Dogs - blood; Dogs - physiology; Dogs - urine; Drug Interactions; DRUGS; HORMONE RECEPTORS; Imidazoles - antagonists & inhibitors; Imidazoles - pharmacology; Male; MEDICAMENT; MEDICAMENTOS; MICTION; ORINACION; PERRO; Potassium - urine; Random Allocation; RECEPTEUR D'HORMONE; RECEPTORES DE HORMONAS; Sodium - urine; URINATION; VASOPRESINA; VASOPRESSIN; VASOPRESSINE; XILAZINA; XYLAZINE; Xylazine - pharmacology; Yohimbine - pharmacology; α2-adrenoceptor agonist and antagonists

The aim of this study was to investigate and compare the antagonistic effects of atipamezole and yohimbine on xylazine-induced diuresis in healthy dogs. Five healthy male beagles were assigned to each of the 8 treatment groups in a randomized design at 1-week intervals in the same dog. One group was...