Combinatorial approaches to evaluate nanodiamond uptake and induced cellular fate

• Published in: Nanotechnology Vol. 27; no. 8; p. 085107
• Main Authors: Eldawud, Reem, Reitzig, Manuela, Opitz, Jörg, Rojansakul, Yon, Jiang, Wenjuan, Nangia, Shikha, Dinu, Cerasela Zoica
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 26.02.2016
• Subjects: Biocompatibility; Biological Transport; Bronchi - cytology; Bronchi - drug effects; Carbon - chemistry; Carbon - pharmacology; Cell Cycle - drug effects; Cell Line, Transformed; Cell Proliferation - drug effects; Cell Survival - drug effects; cell-based sensing; Cellular; Combinatorial analysis; course grained simulation; Electric Impedance; Epithelial Cells - cytology; Epithelial Cells - drug effects; Explosive Agents - chemistry; Flow Cytometry; Humans; Kinetics; Membrane Fluidity; Membranes; Models, Biological; nanodiamonds; Nanodiamonds - chemistry; Nanostructure; Neodymium; Particle Size; Phosphatidylcholines - chemistry; Real time; Thermodynamics; Uptakes

Nanodiamonds (NDs) are an emerging class of engineered nanomaterials that hold great promise for the next generation of bionanotechnological products to be used for drug and gene delivery, or for bio-imaging and biosensing. Previous studies have shown that upon their cellular uptake, NDs exhibit hig...