Breathomics to diagnose systemic sclerosis using thermal desorption and comprehensive two-dimensional gas chromatography high-resolution time-of-flight mass spectrometry - Zanella, Delphine; Guiot, Julien; Stefanuto, Pierre-Hugues; Giltay, Laurie; Henket, Monique; Guissard, Françoise; André, Béatrice; Malaise, Michel; Potjewijd, Judith; Schleich, Florence; Louis, Renaud; Focant, Jean-François (Analytical and bioanalytical chemistry, 2021)
Keywords: air; Air monitoring; Analytical Chemistry; Autoimmune diseases; Biochemistry; Biomarkers; Characterization and Evaluation of Materials; Chemical composition; Chemical compounds; Chemistry; Chemistry and Materials Science; Chimie; Chromatography; comprehensive two-dimensional gas chromatography; desorption; Diagnosis; Discriminant analysis; disease progression; disease severity; early diagnosis; Food Science; Gas chromatography; High resolution; Laboratory Medicine; Lung diseases; Mass spectrometry; Mass spectroscopy; Methods; Monitoring/Environmental Analysis; mortality; Organic compounds; Physical, chemical, mathematical & earth Sciences; Physique, chimie, mathématiques & sciences de la terre; prognosis; Research Paper; Resolution; respiratory tract diseases; Scientific imaging; Scleroderma; Scleroderma (Disease); sclerosis; Spectroscopy; Systemic scleroderma; Systemic sclerosis; t-test; Terpenes; terpenoids; Time-of-flight mass spectrometry; Two dimensional bodies; variance; VOCs; Volatile organic compounds; Belgium; Volatile organic compounds; Biomarkers; High-resolution mass spectrometry; Comprehensive two-dimensional gas chromatography; Systemic sclerosis; Exhaled breath