Successful Conversion From Parenteral Paricalcitol to Pulse Oral Calcitriol for the Management of Secondary Hyperparathyroidism in Hemodialysis Patients

• Published in: Journal of renal nutrition Vol. 26; no. 4; p. 265
• Main Authors: Kumar, Jennifer, Tran, Ngoc-Tram Gia, Schomberg, John, Streja, Elani, Kalantar-Zadeh, Kamyar, Pahl, Madeleine
• Format: Journal Article
• Language: English
• Published: United States 01.07.2016
• Subjects: Administration, Intravenous; Administration, Oral; Adult; Aged; Alkaline Phosphatase - blood; Calcitriol - administration & dosage; Calcitriol - therapeutic use; Calcium - blood; Disease Management; Ergocalciferols - administration & dosage; Ergocalciferols - therapeutic use; Female; Humans; Hyperparathyroidism, Secondary - drug therapy; Male; Middle Aged; Parathyroid Hormone - blood; Parenteral Nutrition; Phosphorus - blood; Receptors, Calcitriol - agonists; Receptors, Calcitriol - blood; Renal Dialysis; Retrospective Studies; Treatment Outcome

The management of hyperparathyroidism in hemodialysis patients involves the administration of phosphate binders, vitamin D receptor activators, and calcimimetics. Intravenous paricalcitol has been preferred over oral calcitriol as it may cause less hypercalcemia and hyperphosphatemia. However, there...