Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody - Kwon, Young D.; Chuang, Gwo-Yu; Zhang, Baoshan; Bailer, Robert T.; Doria-Rose, Nicole A.; Gindin, Tatyana S.; Lin, Bob; Louder, Mark K.; McKee, Krisha; O’Dell, Sijy; Pegu, Amarendra; Schmidt, Stephen D.; et al. (Cell reports (Cambridge), 2018)
Keywords: 10E8; Antibodies, Neutralizing - immunology; antibody improvement; BASIC BIOLOGICAL SCIENCES; broadly neutralizing antibody; Cell Membrane - metabolism; Half-Life; HIV Antibodies - immunology; HIV Envelope Protein gp41 - metabolism; HIV-1; HIV-1 - immunology; Humans; membrane-proximal external region; MPER; Neutralization Tests; Polysaccharides - metabolism; Protein Binding; surface-matrix screening; HIV-1; broadly neutralizing antibody; membrane-proximal external region; antibody improvement; MPER; 10E8; surface-matrix screening