Real-time maps of fluid flow fields in porous biomaterials

• Published in: Biomaterials Vol. 34; no. 8; pp. 1980 - 1986
• Main Authors: Mack, Julia J, Youssef, Khalid, Noel, Onika D.V, Lake, Michael P, Wu, Ashley, Iruela-Arispe, M. Luisa, Bouchard, Louis-S
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.03.2013
• Subjects: 3D scaffold; Advanced Basic Science; Biocompatible Materials - chemistry; Biomaterials; Biomedical materials; Biopolymers - chemistry; Computer Systems; Dentistry; Extracellular Fluid - physiology; Flow; Fluid dynamics; Fluid flow; Fluid permeability; Fluids; Hydrodynamics; Hydrogel; Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry; Magnetic Resonance Spectroscopy; NMR; Polyesters - chemistry; Porosity; Rheology; Shear; Surgical implants; Three dimensional; Tissue Scaffolds - chemistry; NMR; Hydrogel; 3D scaffold; Fluid permeability; Flow

Abstract Mechanical forces such as fluid shear have been shown to enhance cell growth and differentiation, but knowledge of their mechanistic effect on cells is limited because the local flow patterns and associated metrics are not precisely known. Here we present real-time, non-invasive measures of...