Additive Role of a Potentially Reversible Cognitive Frailty Model and Inflammatory State on the Risk of Disability: The Italian Longitudinal Study on Aging

• Published in: The American journal of geriatric psychiatry Vol. 25; no. 11; p. 1236
• Main Authors: Solfrizzi, Vincenzo, Scafato, Emanuele, Lozupone, Madia, Seripa, Davide, Giannini, Michele, Sardone, Rodolfo, Bonfiglio, Caterina, Abbrescia, Daniela I, Galluzzo, Lucia, Gandin, Claudia, Baldereschi, Marzia, Di Carlo, Antonio, Inzitari, Domenico, Daniele, Antonio, Sabbà, Carlo, Logroscino, Giancarlo, Panza, Francesco
• Format: Journal Article
• Language: English
• Published: England 01.11.2017
• Subjects: Aged; Aged, 80 and over; Aging - physiology; Cognitive Dysfunction - epidemiology; Comorbidity; Disabled Persons - statistics & numerical data; Female; Follow-Up Studies; Frail Elderly - statistics & numerical data; Frailty - classification; Frailty - epidemiology; Humans; Inflammation - epidemiology; Italy - epidemiology; Longitudinal Studies; Male; Prevalence; Risk; Frailty; Alzheimer disease; inflammation; cognitive aging; disablement process; lifestyle

Cognitive frailty is a condition recently defined by operationalized criteria describing the simultaneous presence of physical frailty and mild cognitive impairment (MCI). Two subtypes for this clinical construct have been proposed: "potentially reversible" cognitive frailty (physical frai...