Brain-Derived Neurotrophic Factor: A Key Molecule for Memory in the Healthy and the Pathological Brain

• Published in: Frontiers in cellular neuroscience Vol. 13; p. 363
• Main Authors: Miranda, Magdalena, Morici, Juan Facundo, Zanoni, María Belén, Bekinschtein, Pedro
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 07.08.2019; Frontiers Media S.A
• Subjects: Aging; Alzheimer disease; Animal cognition; BDNF; Brain-derived neurotrophic factor; depression; Epigenetics; Gene expression; hippocampus; Kinases; Memory; Mental disorders; Neuroscience; Neurosciences; Parahippocampal gyrus; perirhinal cortex; Plasticity; Proteins; Schizophrenia; stress; memory; hippocampus; Alzheimer disease; BDNF; depression; perirhinal cortex

Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes related to learning and memory. The expression of BDNF is highly regulated, and can lead to great variability in BDNF levels in healthy subjects. Changes in BDNF expression are associated with both normal and path...