What Every Neuropathologist Needs to Know: The Muscle Biopsy
Abstract Competence in muscle biopsy evaluation is a core component of neuropathology practice. The practicing neuropathologist should be able to prepare frozen sections of muscle biopsies with minimal artifacts and identify key histopathologic features of neuromuscular disease in hematoxylin and eo...
Saved in:
| Published in | Journal of neuropathology and experimental neurology Vol. 79; no. 7; pp. 719 - 733 |
|---|---|
| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
England
Oxford University Press
01.07.2020
by American Association of Neuropathologists, Inc |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Abstract
Competence in muscle biopsy evaluation is a core component of neuropathology practice. The practicing neuropathologist should be able to prepare frozen sections of muscle biopsies with minimal artifacts and identify key histopathologic features of neuromuscular disease in hematoxylin and eosin-stained sections as well as implement and interpret a basic panel of additional histochemical, enzyme histochemical, and immunohistochemical stains. Important to everyday practice is a working knowledge of normal muscle histology at different ages, muscle motor units, pitfalls of myotendinous junctions, nonpathologic variations encountered at traditional and nontraditional muscle sites, the pathophysiology of myonecrosis and regeneration, and approaches to distinguish muscular dystrophies from inflammatory myopathies and other necrotizing myopathies. Here, we provide a brief overview of what every neuropathologist needs to know concerning the muscle biopsy. |
|---|---|
| AbstractList | Competence in muscle biopsy evaluation is a core component of neuropathology practice. The practicing neuropathologist should be able to prepare frozen sections of muscle biopsies with minimal artifacts and identify key histopathologic features of neuromuscular disease in hematoxylin and eosin-stained sections as well as implement and interpret a basic panel of additional histochemical, enzyme histochemical, and immunohistochemical stains. Important to everyday practice is a working knowledge of normal muscle histology at different ages, muscle motor units, pitfalls of myotendinous junctions, nonpathologic variations encountered at traditional and nontraditional muscle sites, the pathophysiology of myonecrosis and regeneration, and approaches to distinguish muscular dystrophies from inflammatory myopathies and other necrotizing myopathies. Here, we provide a brief overview of what every neuropathologist needs to know concerning the muscle biopsy. Abstract Competence in muscle biopsy evaluation is a core component of neuropathology practice. The practicing neuropathologist should be able to prepare frozen sections of muscle biopsies with minimal artifacts and identify key histopathologic features of neuromuscular disease in hematoxylin and eosin-stained sections as well as implement and interpret a basic panel of additional histochemical, enzyme histochemical, and immunohistochemical stains. Important to everyday practice is a working knowledge of normal muscle histology at different ages, muscle motor units, pitfalls of myotendinous junctions, nonpathologic variations encountered at traditional and nontraditional muscle sites, the pathophysiology of myonecrosis and regeneration, and approaches to distinguish muscular dystrophies from inflammatory myopathies and other necrotizing myopathies. Here, we provide a brief overview of what every neuropathologist needs to know concerning the muscle biopsy. Competence in muscle biopsy evaluation is a core component of neuropathology practice. The practicing neuropathologist should be able to prepare frozen sections of muscle biopsies with minimal artifacts and identify key histopathologic features of neuromuscular disease in hematoxylin and eosin-stained sections as well as implement and interpret a basic panel of additional histochemical, enzyme histochemical, and immunohistochemical stains. Important to everyday practice is a working knowledge of normal muscle histology at different ages, muscle motor units, pitfalls of myotendinous junctions, nonpathologic variations encountered at traditional and nontraditional muscle sites, the pathophysiology of myonecrosis and regeneration, and approaches to distinguish muscular dystrophies from inflammatory myopathies and other necrotizing myopathies. Here, we provide a brief overview of what every neuropathologist needs to know concerning the muscle biopsy. Key Words: Inflammatory myopathy, Muscle biopsy, Muscular dystrophy, Myopathy, Neurogenic atrophy. |
| Audience | Academic |
| Author | Nix, James S Moore, Steven A |
| AuthorAffiliation | Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland Department of Pathology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa |
| AuthorAffiliation_xml | – name: Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland Department of Pathology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa – name: n2 Department of Pathology, Carver College of Medicine, The University of Iowa , Iowa City, Iowa – name: n1 Department of Pathology, Johns Hopkins University School of Medicine , Baltimore, Maryland |
| Author_xml | – sequence: 1 givenname: James S surname: Nix fullname: Nix, James S organization: Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland – sequence: 2 givenname: Steven A orcidid: 0000-0002-6353-7900 surname: Moore fullname: Moore, Steven A email: steven-moore@uiowa.edu organization: Department of Pathology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32529201$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kk1v1DAQhi1URLeFG2cUiQMcSDtxnA9XCKlU5UMUuKzE0XLsySaL1w520tX-exztUihCyAfL42femfHrE3JknUVCnmZwlgHPz9cW7bk1UgIrH5BFVhQsLYuqPiILAErTHEp-TE5CWAMAB84ekeOcFpRTyBbk9bdOjsn1Lfpd8gUn7wY5ds64VR_GGEAdktEln6zbXiTLDpPPU1AGk7e9G8LuMXnYShPwyWE_Jct318urD-nN1_cfry5vUlUUJU15WdQVIq0a3cTOWp61FVe0Aa65bvNa5wgtbbUqFUgGrFGNrijTHDBHneen5M1edpiaDWqFdvTSiMH3G-l3wsle3L-xfSdW7lZUOTBel1Hg5UHAux8ThlFs-qDQGGnRTUFQllHOswzmWs__Qtdu8jZOFylaFgWHvPxNraRB0dvWxbpqFhWXJWOU1jWdtc7-QcWlcdOr6GLbx_i9hFf7BOVdCB7buxkzELPZYjZbHMyO-LM_3-UO_uVuBNge2Dozog_fzbRFLzqUZuxE_A5QQEVTChSgiqd0DtGY9mKf5qbh_x38BIgTw7E |
| CitedBy_id | crossref_primary_10_1007_s00418_021_02027_3 crossref_primary_10_3390_ijms25094930 crossref_primary_10_1016_j_mpdhp_2023_09_001 crossref_primary_10_1016_j_ncl_2021_08_010 crossref_primary_10_1186_s40478_022_01360_5 crossref_primary_10_36290_neu_2021_050 crossref_primary_10_54097_hset_v14i_1591 crossref_primary_10_1016_j_berh_2022_101764 crossref_primary_10_3390_ijms24032415 crossref_primary_10_1186_s40478_022_01320_z crossref_primary_10_1111_nan_12888 crossref_primary_10_7554_eLife_92674 crossref_primary_10_1007_s00424_021_02623_1 crossref_primary_10_3892_etm_2024_12385 crossref_primary_10_7554_eLife_92674_3 crossref_primary_10_1186_s42047_020_00085_w crossref_primary_10_3233_JND_210641 crossref_primary_10_3390_proteomes12010004 crossref_primary_10_5851_fl_2022_e3 |
| Cites_doi | 10.1002/cphy.c140048 10.1007/s11910-010-0154-y 10.1007/s11926-018-0732-6 10.1177/088307389100600407 10.1016/j.jaut.2013.11.005 10.1016/j.ncl.2014.04.010 10.1002/mus.24497 10.1016/j.spen.2011.10.006 10.1038/s41584-019-0186-x 10.1097/WCO.0b013e32830dd5a6 10.1001/archneurol.2011.74 10.1007/s00415-011-6193-8 10.1016/0049-0172(87)90008-4 10.1111/nan.12587 10.1055/s-0032-1329197 10.1093/jnen/nlv020 10.1002/humu.20976 10.1128/CMR.00026-08 10.1016/j.autrev.2014.12.004 10.1186/1750-1172-7-54 10.1016/S0140-6736(03)14368-1 10.1136/jnnp.60.6.655 10.1136/jmedgenet-2015-103387 10.1016/j.ncl.2014.05.002 10.1186/1750-1172-2-25 10.1212/WNL.58.12.1773 10.3109/07853890.2011.605389 10.1016/j.ajhg.2018.03.011 10.1097/01.jnen.0000200151.60142.25 10.1073/pnas.1001517107 10.1186/2051-5960-2-2 10.1097/BOR.0b013e32834bab42 10.1001/archneur.1969.00480150025002 10.1016/S0960-8966(02)00135-9 10.1111/nan.12380 10.1002/cphy.c140068 10.1002/mus.26083 10.1016/j.pmr.2012.06.006 10.1016/S1474-4422(03)00585-4 |
| ContentType | Journal Article |
| Copyright | 2020 American Association of Neuropathologists, Inc. 2020 2020 by American Association of Neuropathologists, Inc. 2020 American Association of Neuropathologists, Inc. COPYRIGHT 2020 Oxford University Press |
| Copyright_xml | – notice: 2020 American Association of Neuropathologists, Inc. 2020 – notice: 2020 by American Association of Neuropathologists, Inc. – notice: 2020 American Association of Neuropathologists, Inc. – notice: COPYRIGHT 2020 Oxford University Press |
| DBID | TOX CGR CUY CVF ECM EIF NPM AAYXX CITATION 3V. 7X7 7XB 88E 88G 88I 8AF 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH GNUQQ HCIFZ K9. M0S M1P M2P PQEST PQQKQ PQUKI PRINS Q9U S0X 7X8 5PM |
| DOI | 10.1093/jnen/nlaa046 |
| DatabaseName | Oxford Academic Journals (Open Access) Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef ProQuest Central (Corporate) Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Psychology Database (Alumni) Science Database (Alumni Edition) STEM Database Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central ProQuest Central Essentials ProQuest Central ProQuest One Community College ProQuest Central Korea Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) Health & Medical Collection (Alumni Edition) Medical Database Science Database ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic SIRS Editorial MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef ProQuest Central Student ProQuest Central Essentials SIRS Editorial ProQuest Health & Medical Complete (Alumni) ProQuest AP Science ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest Central China ProQuest Central Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea ProQuest Medical Library (Alumni) ProQuest Science Journals (Alumni Edition) ProQuest Central Basic ProQuest Science Journals ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Psychology Journals (Alumni) ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest One Academic ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | CrossRef MEDLINE ProQuest Central Student |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: TOX name: Oxford Academic Journals (Open Access) url: https://academic.oup.com/journals/ sourceTypes: Publisher – sequence: 4 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1554-6578 |
| EndPage | 733 |
| ExternalDocumentID | A644228823 10_1093_jnen_nlaa046 32529201 00005072-202007000-00002 10.1093/jnen/nlaa046 |
| Genre | Review Research Support, Non-U.S. Gov't Journal Article Research Support, N.I.H., Extramural |
| GeographicLocations | United States |
| GeographicLocations_xml | – name: United States |
| GrantInformation_xml | – fundername: NINDS NIH HHS grantid: U54 NS053672 – fundername: ; – fundername: ; grantid: U54, NS053672 |
| GroupedDBID | --- .Z2 01R 0R~ 29L 48X 5GY 5RE 5WD 71W 77Y 7X7 88E 88I 8AF 8FI 8FJ 8R4 8R5 AABZA AACZT AAIMJ AAMDB AAMVS AAPQZ AAPXW AARHZ AASNB AASOK AAUAY AAUQX AAVAP ABBUW ABEUO ABIVO ABIXL ABJNI ABLJU ABMNT ABNHQ ABPTD ABQNK ABUWG ABWST ABXVV ACDDN ACGFO ACGFS ACGOD ACUFI ACUTJ ACWDW ACWRI ADBBV ADGZP ADHKW ADIPN ADQBN ADRTK ADVEK AELWJ AEMDU AENEX AENZO AEPUE AETBJ AEWNT AFFZL AFGWE AFIYH AFKRA AFOFC AFXEN AGINI AGINJ AGQXC AGSYK AGUTN AHMBA AHVBC AJEEA ALIPV ALMA_UNASSIGNED_HOLDINGS ALUQC APIBT ARIXL ATGXG AVWKF AYOIW AZQEC BAYMD BCRHZ BENPR BHONS BOYCO BPHCQ BQDIO BSWAC BTRTY BVRKM BVXVI C45 CCPQU CDBKE CS3 DAKXR DILTD DU5 DWQXO E.X EBS EJD ENERS EX3 F2K F2L F2M F2N F5P FECEO FHSFR FL- FLUFQ FOEOM FOTVD FQBLK FYUFA GAUVT GJXCC GNUQQ H0~ H13 HCIFZ HMCUK HZ~ IAO IHR INH IN~ J21 K8S KBUDW KD2 KMI KOP KQ8 KSI KSN L7B M1P M2M M2P M2Q MHKGH N9A NLBLG NOMLY NOYVH N~7 N~B OAUYM OAWHX OBOKY OCZFY ODMLO OJQWA OJZSN OK1 OLH OLV OLZ OPAEJ OVD OWPYF P2P PAFKI PEELM PQQKQ PROAC PSQYO Q2X ROX ROZ RUSNO RWL S0X S4S TAE TEORI TLC TOX UKHRP V2I W3M WH7 WOQ WOW YAYTL YKOAZ YXANX - 1AW 40H 7O 7O~ AABJS AABMN ABFLS ABZAD ACIMA ADEIU ADJQC ADORX ADQLU ADRIX AELNO AGVJH AIKOY AIMBJ ASMCH AWKKM AZQFJ BGYMP DPPUQ H0 HZ IN JK3 RIG RLZ S4R X3V X3W Z2 ZA5 5VS CGR CUY CVF ECM EIF ITC NPM AAYXX CITATION AAESY ABSAR ABXZS ALXQX BYORX CASEJ 3V. 7XB 8FK K9. PQEST PQUKI PRINS Q9U 7X8 5PM |
| ID | FETCH-LOGICAL-c5562-96587ee27bdb657f91f79c2b09d9df38d3e0f2fdc6c0a404bcbd724d90e3ed33 |
| IEDL.DBID | 7X7 |
| ISSN | 0022-3069 |
| IngestDate | Tue Sep 17 21:13:05 EDT 2024 Fri Oct 25 03:01:00 EDT 2024 Thu Oct 10 20:26:15 EDT 2024 Thu Feb 22 23:28:59 EST 2024 Wed Jan 10 04:01:08 EST 2024 Thu Sep 26 15:42:44 EDT 2024 Wed Oct 16 00:43:06 EDT 2024 Thu Aug 13 19:51:10 EDT 2020 Wed Sep 11 04:48:25 EDT 2024 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 7 |
| Keywords | Neurogenic atrophy Muscle biopsy Inflammatory myopathy Muscular dystrophy Myopathy |
| Language | English |
| License | This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com 2020 American Association of Neuropathologists, Inc. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c5562-96587ee27bdb657f91f79c2b09d9df38d3e0f2fdc6c0a404bcbd724d90e3ed33 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
| ORCID | 0000-0002-6353-7900 |
| OpenAccessLink | https://dx.doi.org/10.1093/jnen/nlaa046 |
| PMID | 32529201 |
| PQID | 2426559036 |
| PQPubID | 40718 |
| PageCount | 15 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_7304986 proquest_miscellaneous_2412991103 proquest_journals_2426559036 gale_infotracmisc_A644228823 gale_infotracacademiconefile_A644228823 crossref_primary_10_1093_jnen_nlaa046 pubmed_primary_32529201 wolterskluwer_health_00005072-202007000-00002 oup_primary_10_1093_jnen_nlaa046 |
| ProviderPackageCode | C45 .Z2 7O~ N~7 OLH AWKKM 40H ABZAD ABBUW JK3 N~B H0~ OLV X3V OLZ X3W F2K ACDDN ACWRI BOYCO F2M F2L F2N FL- KMI K8S V2I E.X S4R 01R S4S IN~ KD2 77Y ACWDW OVD 71W |
| PublicationCentury | 2000 |
| PublicationDate | 2020-July-01 |
| PublicationDateYYYYMMDD | 2020-07-01 |
| PublicationDate_xml | – month: 07 year: 2020 text: 2020-July-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England – name: Cary |
| PublicationTitle | Journal of neuropathology and experimental neurology |
| PublicationTitleAlternate | J Neuropathol Exp Neurol |
| PublicationYear | 2020 |
| Publisher | Oxford University Press by American Association of Neuropathologists, Inc |
| Publisher_xml | – name: Oxford University Press – name: by American Association of Neuropathologists, Inc |
| References | 33011796 - J Neuropathol Exp Neurol. 2021 Mar 22;80(4):387 Pfeffer (2024032523331738800_nlaa046-B22) 2013; 45 Pinal-Fernandez (2024032523331738800_nlaa046-B41) 2018; 20 Cenacchi (2024032523331738800_nlaa046-B18) 2020; 46 Pestronk (2024032523331738800_nlaa046-B39) 2011; 23 Allenbach (2024032523331738800_nlaa046-B10) 2017; 43 Zalneraitis (2024032523331738800_nlaa046-B4) 1991; 6 Iaccarino (2024032523331738800_nlaa046-B8) 2014; 48–49 Jungbluth (2024032523331738800_nlaa046-B16) 2007; 2 Romero (2024032523331738800_nlaa046-B15) 2011; 18 Meng (2024032523331738800_nlaa046-B3) 2014 Bruno (2024032523331738800_nlaa046-B24) 2008; 21 Dalakas (2024032523331738800_nlaa046-B9) 2003; 362 Sewry (2024032523331738800_nlaa046-B17) 2002; 12 Kolb (2024032523331738800_nlaa046-B6) 2011; 68 Wolfe (2024032523331738800_nlaa046-B13) 1987; 16 Silverstein (2024032523331738800_nlaa046-B14) 1969; 21 Flanigan (2024032523331738800_nlaa046-B35) 2014; 32 Dimachkie (2024032523331738800_nlaa046-B12) 2012; 32 Tuffery-Giraud (2024032523331738800_nlaa046-B36) 2009; 30 Gottstein (2024032523331738800_nlaa046-B29) 2009; 22 Meola (2024032523331738800_nlaa046-B1) 2012; 259 Henderson (2024032523331738800_nlaa046-B38) 2010; 107 Aartsma-Rus (2024032523331738800_nlaa046-B33) 2016; 53 Burns (2024032523331738800_nlaa046-B7) 2018; 102 Dasouki (2024032523331738800_nlaa046-B20) 2014; 32 Arnold (2024032523331738800_nlaa046-B5) 2015; 51 Gertz (2024032523331738800_nlaa046-B28) 1996; 60 Dumont (2024032523331738800_nlaa046-B30) 2015; 5 Sugie (2024032523331738800_nlaa046-B19) 2002; 58 Liang (2024032523331738800_nlaa046-B23) 2011; 11 Desport (2024032523331738800_nlaa046-B27) 2012; 7 Feeney (2024032523331738800_nlaa046-B21) 2014; 2 Tanboon (2024032523331738800_nlaa046-B40) 2019; 32 Vital (2024032523331738800_nlaa046-B26) 2006; 65 Lawlor (2024032523331738800_nlaa046-B37) 2016; 75 Joyce (2024032523331738800_nlaa046-B2) 2012; 23 Greenberg (2024032523331738800_nlaa046-B11) 2019; 15 Gao (2024032523331738800_nlaa046-B31) 2015; 5 Greco (2024032523331738800_nlaa046-B25) 2015; 14 Muntoni (2024032523331738800_nlaa046-B32) 2003; 2 Carlson (2024032523331738800_nlaa046-B34) 2018; 58 |
| References_xml | – volume: 5 start-page: 1223 year: 2015 ident: 2024032523331738800_nlaa046-B31 article-title: The dystrophin complex: Structure, function, and implications for therapy publication-title: Compr Physiol doi: 10.1002/cphy.c140048 contributor: fullname: Gao – volume: 11 start-page: 97 year: 2011 ident: 2024032523331738800_nlaa046-B23 article-title: Lipid storage myopathy publication-title: Curr Neurol Neurosci Rep doi: 10.1007/s11910-010-0154-y contributor: fullname: Liang – volume: 20 start-page: 21 year: 2018 ident: 2024032523331738800_nlaa046-B41 article-title: Immune-mediated necrotizing myopathy publication-title: Curr Rheumatol Rep doi: 10.1007/s11926-018-0732-6 contributor: fullname: Pinal-Fernandez – volume: 6 start-page: 324 year: 1991 ident: 2024032523331738800_nlaa046-B4 article-title: Muscle biopsy and the clinical course of infantile spinal muscular atrophy publication-title: J Child Neurol doi: 10.1177/088307389100600407 contributor: fullname: Zalneraitis – volume: 48–49 start-page: 122 year: 2014 ident: 2024032523331738800_nlaa046-B8 article-title: The clinical features, diagnosis and classification of dermatomyositis publication-title: J Autoimmun doi: 10.1016/j.jaut.2013.11.005 contributor: fullname: Iaccarino – volume: 32 start-page: 751 year: 2014 ident: 2024032523331738800_nlaa046-B20 article-title: Pompe disease: Literature review and case series publication-title: Neurol Clin doi: 10.1016/j.ncl.2014.04.010 contributor: fullname: Dasouki – volume: 51 start-page: 157 year: 2015 ident: 2024032523331738800_nlaa046-B5 article-title: Spinal muscular atrophy: Diagnosis and management in a new therapeutic era publication-title: Muscle Nerve doi: 10.1002/mus.24497 contributor: fullname: Arnold – volume: 18 start-page: 250 year: 2011 ident: 2024032523331738800_nlaa046-B15 article-title: Centronuclear myopathies publication-title: Semin Pediatr Neurol doi: 10.1016/j.spen.2011.10.006 contributor: fullname: Romero – volume: 15 start-page: 257 year: 2019 ident: 2024032523331738800_nlaa046-B11 article-title: Inclusion body myositis: Clinical features and pathogenesis publication-title: Nat Rev Rheumatol doi: 10.1038/s41584-019-0186-x contributor: fullname: Greenberg – volume: 21 start-page: 601 year: 2008 ident: 2024032523331738800_nlaa046-B24 article-title: Lipid storage myopathies publication-title: Curr Opin Neurol doi: 10.1097/WCO.0b013e32830dd5a6 contributor: fullname: Bruno – volume: 32 start-page: 704 year: 2019 ident: 2024032523331738800_nlaa046-B40 article-title: Classification of idiopathic inflammatory myopathies: Pathology perspectives publication-title: Curr Opin Rheumatol contributor: fullname: Tanboon – volume: 68 start-page: 979 year: 2011 ident: 2024032523331738800_nlaa046-B6 article-title: Spinal muscular atrophy: A timely review publication-title: Arch Neurol doi: 10.1001/archneurol.2011.74 contributor: fullname: Kolb – volume: 259 start-page: 601 year: 2012 ident: 2024032523331738800_nlaa046-B1 article-title: Muscle biopsy publication-title: J Neurol doi: 10.1007/s00415-011-6193-8 contributor: fullname: Meola – volume: 16 start-page: 300 year: 1987 ident: 2024032523331738800_nlaa046-B13 article-title: Myopathy in sarcoidosis: Clinical and pathologic study of four cases and review of the literature publication-title: Semin Arthritis Rheum doi: 10.1016/0049-0172(87)90008-4 contributor: fullname: Wolfe – volume: 46 start-page: 303 year: 2020 ident: 2024032523331738800_nlaa046-B18 article-title: Review: Danon disease: Review of natural history and recent advances publication-title: Neuropathol Appl Neurobiol doi: 10.1111/nan.12587 contributor: fullname: Cenacchi – volume: 32 start-page: 237 year: 2012 ident: 2024032523331738800_nlaa046-B12 article-title: Inclusion body myositis publication-title: Semin Neurol doi: 10.1055/s-0032-1329197 contributor: fullname: Dimachkie – volume: 75 start-page: 102 year: 2016 ident: 2024032523331738800_nlaa046-B37 article-title: Skeletal muscle pathology in X-linked myotubular myopathy: Review with cross-species comparisons publication-title: J Neuropathol Exp Neurol doi: 10.1093/jnen/nlv020 contributor: fullname: Lawlor – volume: 30 start-page: 934 year: 2009 ident: 2024032523331738800_nlaa046-B36 article-title: Genotype-phenotype analysis in 2,405 patients with a dystrophinopathy using the UMD-DMD database: A model of nationwide knowledgebase publication-title: Hum Mutat doi: 10.1002/humu.20976 contributor: fullname: Tuffery-Giraud – volume: 22 start-page: 127 year: 2009 ident: 2024032523331738800_nlaa046-B29 article-title: Epidemiology, diagnosis, treatment, and control of trichinellosis publication-title: CMR doi: 10.1128/CMR.00026-08 contributor: fullname: Gottstein – volume: 14 start-page: 341 year: 2015 ident: 2024032523331738800_nlaa046-B25 article-title: Churg-Strauss syndrome publication-title: Autoimmun Rev doi: 10.1016/j.autrev.2014.12.004 contributor: fullname: Greco – volume: 7 start-page: 54 year: 2012 ident: 2024032523331738800_nlaa046-B27 article-title: AL amyloidosis publication-title: Orphanet J Rare Dis doi: 10.1186/1750-1172-7-54 contributor: fullname: Desport – volume: 362 start-page: 971 year: 2003 ident: 2024032523331738800_nlaa046-B9 article-title: Polymyositis and dermatomyositis publication-title: Lancet doi: 10.1016/S0140-6736(03)14368-1 contributor: fullname: Dalakas – volume: 60 start-page: 655 year: 1996 ident: 2024032523331738800_nlaa046-B28 article-title: Myopathy in primary systemic amyloidosis publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp.60.6.655 contributor: fullname: Gertz – volume: 53 start-page: 145 year: 2016 ident: 2024032523331738800_nlaa046-B33 article-title: The importance of genetic diagnosis for Duchenne muscular dystrophy publication-title: J Med Genet doi: 10.1136/jmedgenet-2015-103387 contributor: fullname: Aartsma-Rus – volume: 32 start-page: 671 year: 2014 ident: 2024032523331738800_nlaa046-B35 article-title: Duchenne and Becker muscular dystrophies publication-title: Neurol Clin doi: 10.1016/j.ncl.2014.05.002 contributor: fullname: Flanigan – volume: 2 start-page: 25 year: 2007 ident: 2024032523331738800_nlaa046-B16 article-title: Central core disease publication-title: Orphanet J Rare Dis doi: 10.1186/1750-1172-2-25 contributor: fullname: Jungbluth – volume: 58 start-page: 1773 year: 2002 ident: 2024032523331738800_nlaa046-B19 article-title: Clinicopathological features of genetically confirmed Danon disease publication-title: Neurology doi: 10.1212/WNL.58.12.1773 contributor: fullname: Sugie – volume: 45 start-page: 4 year: 2013 ident: 2024032523331738800_nlaa046-B22 article-title: Diagnosis and treatment of mitochondrial myopathies publication-title: Ann Med doi: 10.3109/07853890.2011.605389 contributor: fullname: Pfeffer – volume: 102 start-page: 858 year: 2018 ident: 2024032523331738800_nlaa046-B7 article-title: Variants in EXOSC9 disrupt the RNA exosome and result in cerebellar atrophy with spinal motor neuronopathy publication-title: Am J Hum Genet doi: 10.1016/j.ajhg.2018.03.011 contributor: fullname: Burns – volume: 65 start-page: 187 year: 2006 ident: 2024032523331738800_nlaa046-B26 article-title: Neuro-muscular biopsy in Churg-Strauss syndrome: 24 cases publication-title: J Neuropathol Exp Neurol doi: 10.1097/01.jnen.0000200151.60142.25 contributor: fullname: Vital – volume: 107 start-page: 9632 year: 2010 ident: 2024032523331738800_nlaa046-B38 article-title: Disease-causing missense mutations in actin binding domain 1 of dystrophin induce thermodynamic instability and protein aggregation publication-title: Proc Natl Acad Sci doi: 10.1073/pnas.1001517107 contributor: fullname: Henderson – volume: 2 start-page: 2 year: 2014 ident: 2024032523331738800_nlaa046-B21 article-title: The value of muscle biopsies in Pompe disease: Identifying lipofuscin inclusions in juvenile- and adult-onset patients publication-title: Acta Neuropathol Commun doi: 10.1186/2051-5960-2-2 contributor: fullname: Feeney – volume: 23 start-page: 595 year: 2011 ident: 2024032523331738800_nlaa046-B39 article-title: Acquired immune and inflammatory myopathies: Pathologic classification publication-title: Curr Opin Rheumatol doi: 10.1097/BOR.0b013e32834bab42 contributor: fullname: Pestronk – volume: 21 start-page: 235 year: 1969 ident: 2024032523331738800_nlaa046-B14 article-title: Muscle involvement in sarcoidosis: Asymptomatic, myositis, and myopathy publication-title: Arch Neurol doi: 10.1001/archneur.1969.00480150025002 contributor: fullname: Silverstein – start-page: e51586 year: 2014 ident: 2024032523331738800_nlaa046-B3 article-title: Tissue triage and freezing for models of skeletal muscle disease publication-title: J Vis Exp contributor: fullname: Meng – volume: 12 start-page: 930 year: 2002 ident: 2024032523331738800_nlaa046-B17 article-title: The spectrum of pathology in central core disease publication-title: Neuromuscul Disord doi: 10.1016/S0960-8966(02)00135-9 contributor: fullname: Sewry – volume: 43 start-page: 62 year: 2017 ident: 2024032523331738800_nlaa046-B10 article-title: Integrated classification of inflammatory myopathies publication-title: Neuropathol Appl Neurobiol doi: 10.1111/nan.12380 contributor: fullname: Allenbach – volume: 5 start-page: 1027 year: 2015 ident: 2024032523331738800_nlaa046-B30 article-title: Satellite cells and skeletal muscle regeneration publication-title: Compr Physiol doi: 10.1002/cphy.c140068 contributor: fullname: Dumont – volume: 58 start-page: 149 year: 2018 ident: 2024032523331738800_nlaa046-B34 article-title: Dystrophinopathy muscle biopsies in the genetic testing ERA: One center’s data publication-title: Muscle Nerve doi: 10.1002/mus.26083 contributor: fullname: Carlson – volume: 23 start-page: 609 year: 2012 ident: 2024032523331738800_nlaa046-B2 article-title: Muscle biopsy evaluation in neuromuscular disorders publication-title: Phys Med Rehabil Clin N Am doi: 10.1016/j.pmr.2012.06.006 contributor: fullname: Joyce – volume: 2 start-page: 731 year: 2003 ident: 2024032523331738800_nlaa046-B32 article-title: Dystrophin and mutations: One gene, several proteins, multiple phenotypes publication-title: Lancet Neurol doi: 10.1016/S1474-4422(03)00585-4 contributor: fullname: Muntoni |
| SSID | ssj0009094 |
| Score | 2.467395 |
| SecondaryResourceType | review_article |
| Snippet | Abstract
Competence in muscle biopsy evaluation is a core component of neuropathology practice. The practicing neuropathologist should be able to prepare... Competence in muscle biopsy evaluation is a core component of neuropathology practice. The practicing neuropathologist should be able to prepare frozen... |
| SourceID | pubmedcentral proquest gale crossref pubmed wolterskluwer oup |
| SourceType | Open Access Repository Aggregation Database Index Database Publisher |
| StartPage | 719 |
| SubjectTerms | Biopsy Biopsy - methods Biopsy - standards Brain research Care and treatment Diagnosis Humans Invited Review Methods Muscle, Skeletal - pathology Muscle, Smooth - pathology Nervous system diseases Neuromuscular Diseases - pathology Neuropathology - education Neuropathology - methods Neuropathology - standards |
| Title | What Every Neuropathologist Needs to Know: The Muscle Biopsy |
| URI | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&NEWS=n&CSC=Y&PAGE=fulltext&D=ovft&AN=00005072-202007000-00002 https://www.ncbi.nlm.nih.gov/pubmed/32529201 https://www.proquest.com/docview/2426559036 https://search.proquest.com/docview/2412991103 https://pubmed.ncbi.nlm.nih.gov/PMC7304986 |
| Volume | 79 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwhV1ta9swEBZbC2Mwyt7nNSsabOyTiSLJllUGox0pZZBujAzyTdh6od2Gnc0Jo_--d7aSxgy2j4kUHzmdTo91d88R8sYqHpiFjQRQoEylzHRauWBTWRbMuUyq0mKh8OwiP_8mPy2yRbxwa2Na5cYndo7aNRbvyMd4lAD6BYf7Yfkrxa5RGF2NLTTukv0JZzmmdKmFuiXdZVpu2cJZrmPiO7zEj7_Xvh7XP8uSIfTdOZKiYx5Uu-2Azr9zJx_8aTCu3f7o0tp3Dqezh-Qgokp60pvBI3LH14_JvVmMmz8h75Ghm07BbK9pR8eBjYibvvoHvvCupauGYgvsYwqGQ2frFp5DT6-aZXv9lMzPpvOP52nsm5DaDOBMinwuynuuKlflmQp6EpS2vGLaaRdE4YRngQdnc8tKyWRlK6e4dJp54Z0Qz8he3dT-BaHMw4SMhYJXQYbKIRt-WWZWZgUTupAJebvRnFn27Bimj2oLgxo2UcMJeYdqNbhpQGu2jLn_IAXpp8wJoDLOAeyLhIwGM8HY7WCYwsL8R9Zos2om7sfW3FpPQl5vh_HhmGNW-2aNcwD7gO9nIOV5v8hbQYJn2NZrkhA1WP7tBGTpHo7UV5cdW7fCQGYBctOBoZi-zhWD_wwwOQd3hdfGsdCf8Zf__huH5D7-oE8cHpG91e-1fwXwaFUddXvgiOyfTi--fIVP88-LG4_ED9M |
| link.rule.ids | 230,315,783,787,888,1607,12068,21400,27936,27937,31731,31732,33756,33757,43322,43817,74073,74630 |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwhV1tixMxEA56ByqI-Ha6WjWC4qeluWy22Yggd9Kj6rWIVLhvIa94KrvVbZH79850014XQb822R06mUyezcw8Q8gLJ3lkDjYSQAGTC1Gq3ProcmEq5n0ppHFYKDydjSZfxIez8ixduLUprXLjE9eO2jcO78iHeJQA-gWH-3bxM8euURhdTS00rpJ9pKqCj6_94_Hs0-dL2l2mxJYvnI1USn2Hz_jhtzrUw_qHMQzB786hlFxzr95tB3b-nT1583eDke32-zqxfed4OrlNbiVcSY86Q7hDroT6Lrk2TZHze-QNcnTTMRjuBV0TcmAr4qar_4Efgm_psqHYBPs1BdOh01UL76HH582ivbhP5ifj-btJnjon5K4EQJMjo4sMgUvr7aiUUR1GqRy3THnlY1H5IrDIo3cjx4xgwjrrJRdesVAEXxQHZK9u6vCQUBZgQslixW0U0XrkwzemdKKsWKEqkZGXG83pRcePobu4dqFRwzppOCOvUK0atw1ozZmU_Q9SkIBKHwEu4xzgfpGRQW8mmLvrDVNYmP_IGmxWTacd2epL-8nI8-0wvhyzzOrQrHAOoB_w_gykPOgWeSuo4CU29jrMiOwt_3YC8nT3R-rzr2u-bomhzArk5j1D0V2lK4b_GaByDg4LL45TqT_jj_79N56R65P59FSfvp99fExu4MNdGvGA7C1_rcITAEtL-zTtiD8rMxFz |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwhV1ti9NAEB60B4cg4rvRqisofgrd2910ExHkTlvOl5ZDTrhvS7IveCpJNS1y_96ZZttrEPRrd5uhszOzTzMzzwA8t1oEbtGREAqUqVJZkVYu2FSVOXcuU7q01Cg8m4-Pv6gPZ9lZrH9qY1nlJiauA7VrLL0jH9FVgugXA-4oxLKIk3fTN4ufKU2QokxrHKdxFfa0Gks-gL2jyfzk8yUFLy_Uljucj4tYBo9_6Uffal-P6h9lyQkI71xQMUz3et92IOjflZTXfzeU5W6_r4vcd66q6U24ETEmO-yM4hZc8fVt2J_FLPodeE183WyCRnzB1uQcNJa46XqB8APvWrZsGA3EfsXQjNhs1eJz2NF5s2gv7sLpdHL69jiNUxRSmyG4SYndRXsvdOWqcaZDcRB0YUXFC1e4IHMnPQ8iODu2vFRcVbZyWihXcC-9k_IeDOqm9g-AcY8bMh5yUQUVKkfc-GWZWZXlXBa5SuDFRnNm0XFlmC7HLQ1p2EQNJ_CS1GrIhVBrtoydACiFyKjMIWI0IRD6ywSGvZ1o-ra3zPBg_iNruDk1E72zNZe2lMCz7TI9nCrOat-saA8iIbwJOEq53x3yVpAUGQ35OkhA945_u4E4u_sr9fnXNXe3prRmjnLTnqGYruuVSgE4InSBwYteIse2fy4e_vtnPIV9dAbz6f384yO4Rt_tKoqHMFj-WvnHiJuW1ZPoEH8ADOkVoQ |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=What+Every+Neuropathologist+Needs+to+Know%3A+The+Muscle+Biopsy&rft.jtitle=Journal+of+neuropathology+and+experimental+neurology&rft.au=Nix%2C+James+S&rft.au=Moore%2C+Steven+A&rft.date=2020-07-01&rft.pub=by+American+Association+of+Neuropathologists%2C+Inc&rft.issn=0022-3069&rft.eissn=1554-6578&rft.volume=79&rft.issue=7&rft.spage=719&rft.epage=733&rft_id=info:doi/10.1093%2Fjnen%2Fnlaa046&rft.externalDocID=00005072-202007000-00002 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0022-3069&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0022-3069&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0022-3069&client=summon |