Development of a colloidal gold-immunochromatography assay to detect immunoglobulin G antibodies to Treponema pallidum with TPN17 and TPN47

• Published in: Diagnostic microbiology and infectious disease Vol. 68; no. 3; pp. 193 - 200
• Main Authors: Lin, Li-Rong, Fu, Zuo-Gen, Dan, Bing, Jing, Guang-Jun, Tong, Man-li, Chen, De-Teng, Yu, Yang, Zhang, Chang-Gong, Yang, Tian-Ci, Zhang, Zhong-Ying
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.11.2010; Elsevier
• Subjects: Antibodies, Bacterial - blood; Antigens, Bacterial; Bacteriology; Biological and medical sciences; China; Chromatography - methods; Colloidal gold-immunochromatography assay; FTA-Abs; Fundamental and applied biological sciences. Psychology; Gold Colloid; Immunoassay - methods; Immunoglobulin G - blood; Infectious Disease; Infectious diseases; Internal Medicine; Medical sciences; Microbiology; Miscellaneous; Predictive Value of Tests; Recombinant Proteins; Sensitivity and Specificity; Syphilis - diagnosis; TP-IgG; TPN17; TPN47; Treponema pallidum; Treponema pallidum - immunology; China; TPN47; Colloidal gold-immunochromatography assay; TP-IgG; FTA-Abs; TPN17; Treponema pallidum; Spirochaetales; Antibody; IgG; Infection; Bacteria; Treponemataceae; Detection

Syphilis remains a worldwide public health problem; it is necessary to develop a new diagnostic approach that is easier and faster than conventional tests. Here, we report a new testing method named colloidal gold-immunochromatography assay (GICA) to detect syphilis instead of fluorescent treponemal...