Proteomic Study and Marker Protein Identification of Caenorhabditis elegans Lipid Droplets

• Published in: Molecular & cellular proteomics Vol. 11; no. 8; pp. 317 - 328
• Main Authors: Zhang, Peng, Na, Huimin, Liu, Zhenglong, Zhang, Shuyan, Xue, Peng, Chen, Yong, Pu, Jing, Peng, Gong, Huang, Xun, Yang, Fuquan, Xie, Zhensheng, Xu, Tao, Xu, Pingyong, Ou, Guangshuo, Zhang, Shaobing O., Liu, Pingsheng
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2012; The American Society for Biochemistry and Molecular Biology
• Subjects: Animals; Biomarkers - analysis; Blotting, Western; Butyryl-CoA Dehydrogenase - analysis; Caenorhabditis elegans - metabolism; Caenorhabditis elegans Proteins - analysis; Cytoplasmic Vesicles - metabolism; Cytoplasmic Vesicles - ultrastructure; Lipid Metabolism; Lipids - chemistry; Mass Spectrometry; Microscopy, Confocal; Microscopy, Electron, Transmission; Proteome - analysis; Proteomics - methods

Lipid droplets (LDs) are a neutral lipid storage organelle that is conserved across almost all species. Many metabolic syndromes are directly linked to the over-storage of neutral lipids in LDs. The study of LDs in Caenorhabditis elegans (C. elegans) has been difficult because of the lack of specifi...