Hemodynamic effects of fluoxetine in pulmonary arterial hypertension: an open label pilot study
In order to evaluate the therapeutic potential of fluoxetine in pulmonary arterial hypertension, 13 patients with pulmonary arterial hypertension underwent catheterization before and after 12 (N = 5) or 24 (N = 8) weeks fluoxetine therapy. No change was seen in the primary endpoint of pulmonary vasc...
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| Published in | Pulmonary circulation Vol. 10; no. 4; pp. 1 - 4 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
London, England
SAGE Publications
01.10.2020
John Wiley & Sons, Inc Wiley |
| Subjects | |
| Online Access | Get full text |
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| Abstract | In order to evaluate the therapeutic potential of fluoxetine in pulmonary arterial hypertension, 13 patients with pulmonary arterial hypertension underwent catheterization before and after 12 (N = 5) or 24 (N = 8) weeks fluoxetine therapy. No change was seen in the primary endpoint of pulmonary vascular resistance, other hemodynamic values, or any secondary endpoints. |
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| AbstractList | In order to evaluate the therapeutic potential of fluoxetine in pulmonary arterial hypertension, 13 patients with pulmonary arterial hypertension underwent catheterization before and after 12 (N = 5) or 24 (N = 8) weeks fluoxetine therapy. No change was seen in the primary endpoint of pulmonary vascular resistance, other hemodynamic values, or any secondary endpoints. In order to evaluate the therapeutic potential of fluoxetine in pulmonary arterial hypertension, 13 patients with pulmonary arterial hypertension underwent catheterization before and after 12 (N = 5) or 24 (N = 8) weeks fluoxetine therapy. No change was seen in the primary endpoint of pulmonary vascular resistance, other hemodynamic values, or any secondary endpoints.In order to evaluate the therapeutic potential of fluoxetine in pulmonary arterial hypertension, 13 patients with pulmonary arterial hypertension underwent catheterization before and after 12 (N = 5) or 24 (N = 8) weeks fluoxetine therapy. No change was seen in the primary endpoint of pulmonary vascular resistance, other hemodynamic values, or any secondary endpoints. In order to evaluate the therapeutic potential of fluoxetine in pulmonary arterial hypertension, 13 patients with pulmonary arterial hypertension underwent catheterization before and after 12 (N = 5) or 24 (N = 8) weeks fluoxetine therapy. No change was seen in the primary endpoint of pulmonary vascular resistance, other hemodynamic values, or any secondary endpoints. |
| Author | Igenoza, Oluwatosin P. Sodimu, Adetoun Bartolome, Sonja Chin, Kelly M. |
| Author_xml | – sequence: 1 givenname: Adetoun surname: Sodimu fullname: Sodimu, Adetoun organization: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA – sequence: 2 givenname: Sonja surname: Bartolome fullname: Bartolome, Sonja organization: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA – sequence: 3 givenname: Oluwatosin P. surname: Igenoza fullname: Igenoza, Oluwatosin P. organization: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA – sequence: 4 givenname: Kelly M. orcidid: 0000-0002-1214-6723 surname: Chin fullname: Chin, Kelly M. email: Kelly.chin@utsouthwestern.edu organization: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA |
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| CitedBy_id | crossref_primary_10_1016_S2213_2600_24_00226_1 crossref_primary_10_1016_j_jbspin_2021_105309 crossref_primary_10_1080_17460441_2023_2192919 crossref_primary_10_1152_ajplung_00159_2021 crossref_primary_10_1016_S1877_1203_23_00079_4 crossref_primary_10_1002_pul2_12088 crossref_primary_10_1016_j_ijpharm_2022_121792 crossref_primary_10_3389_fddsv_2022_1022971 |
| Cites_doi | 10.1378/chest.08-2823 10.1161/01.RES.0000126847.27660.69 10.1172/JCI8678 10.1378/chest.11-0426 10.1161/CIRCULATIONAHA.104.524926 10.1161/01.RES.0000222546.45372.a0 10.1161/CIRCULATIONAHA.108.767558 10.1097/01.psy.0000145593.37594.39 10.1183/13993003.01032-2015 10.1177/2045894018759125 10.1016/0167-5273(87)90200-2 10.1016/j.pupt.2006.01.001 10.1378/chest.12-2081 10.1164/rccm.200210-1212OC 10.1136/bmj.f6932 10.1001/jama.2015.5605 10.1056/NEJM199902113400614 |
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| Keywords | right heart catheterization treatment pulmonary hypertension |
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| References | Huybrechts, Bateman, Palmsten 2015; 313 Eddahibi, Hanoun, Lanfumey 2000; 105 Ghofrani, Vonk-Noordegraaf, Behr 2012; 185 Marcos, Adnot, Pham 2003; 168 Sadoughi, Roberts, Preston 2013; 144 Marcos, Fadel, Sanchez 2004; 94 Grigoriadis, Vonderporten, Mamisashvili 2014; 348 Kawut, Horn, Berekashvili 2006; 19 Guignabert, Izikki, Tu 2006; 98 McGoon, Vlietstra 1987; 14 Galie, Humbert, Vachiery 2015; 46 Dempsie, Morecroft, Welsh 2008; 117 Guignabert, Raffestin, Benferhat 2005; 111 Louis 1999; 340 Dhalla, Juurlink, Gomes 2012; 141 Shah, Gomberg-Maitland, Thenappan 2009; 136 MacLean 2018; 8 Lowe, Grafe, Ufer 2004; 66 2015; 46 1987; 14 2004; 66 2012; 185 2012; 141 2018; 8 2014; 348 2004; 94 2005; 111 2015; 313 2006; 98 2000; 105 1999; 340 2013; 144 2008; 117 2006; 19 2003; 168 2009; 136 e_1_2_2_4_1 e_1_2_2_14_1 e_1_2_2_5_1 e_1_2_2_13_1 e_1_2_2_6_1 e_1_2_2_12_1 e_1_2_2_7_1 e_1_2_2_11_1 e_1_2_2_20_1 e_1_2_2_2_1 e_1_2_2_3_1 e_1_2_2_19_1 e_1_2_2_9_1 e_1_2_2_18_1 e_1_2_2_8_1 e_1_2_2_17_1 e_1_2_2_16_1 e_1_2_2_15_1 Ghofrani HAA‐HH (e_1_2_2_10_1) 2012; 185 |
| References_xml | – volume: 105 start-page: 1555 year: 2000 end-page: 1562 article-title: Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene publication-title: J Clin Invest – volume: 185 start-page: A2496 year: 2012 article-title: Proof of concept study to investigate the efficacy, hemodynamics and tolerability of terguride vs. placebo in subjects with pulmonary arterial hypertension: results of a double-blind, randomized, prospective phase IIa study publication-title: Am J Respir Crit Care Med – volume: 117 start-page: 2928 year: 2008 end-page: 2937 article-title: Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice publication-title: Circulation – volume: 141 start-page: 348 year: 2012 end-page: 353 article-title: Selective serotonin reuptake inhibitors and pulmonary arterial hypertension: a case-control study publication-title: Chest – volume: 14 start-page: 303 year: 1987 end-page: 309 article-title: Acute hemodynamic response to the S2-serotonergic receptor antagonist, ketanserin, in patients with primary pulmonary hypertension publication-title: Int J Cardiol – volume: 348 start-page: f6932 year: 2014 end-page: 01 article-title: Prenatal exposure to antidepressants and persistent pulmonary hypertension of the newborn: systematic review and meta-analysis publication-title: BMJ – volume: 98 start-page: 1323 year: 2006 end-page: 1330 article-title: Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension publication-title: Circ Res – volume: 313 start-page: 2142 year: 2015 end-page: 2151 article-title: Antidepressant use late in pregnancy and risk of persistent pulmonary hypertension of the newborn publication-title: JAMA – volume: 8 start-page: 2045894018759125 year: 2018 article-title: The serotonin hypothesis in pulmonary hypertension revisited: targets for novel therapies (2017 Grover Conference Series) publication-title: Pulm Circ – volume: 66 start-page: 831 year: 2004 end-page: 836 article-title: Anxiety and depression in patients with pulmonary hypertension publication-title: Psychosom Med – volume: 19 start-page: 370 year: 2006 end-page: 374 article-title: Selective serotonin reuptake inhibitor use and outcomes in pulmonary arterial hypertension publication-title: Pulm Pharmacol Ther – volume: 136 start-page: 694 year: 2009 end-page: 700 article-title: Selective serotonin reuptake inhibitors and the incidence and outcome of pulmonary hypertension publication-title: Chest – volume: 168 start-page: 487 year: 2003 end-page: 493 article-title: Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension publication-title: Am J Respir Crit Care Med – volume: 340 start-page: 480 year: 1999 end-page: 482 article-title: Primary pulmonary hypertension and anorectic drugs publication-title: N Engl J Med – volume: 144 start-page: 531 year: 2013 end-page: 541 article-title: Use of selective serotonin reuptake inhibitors and outcomes in pulmonary arterial hypertension publication-title: Chest – volume: 111 start-page: 2812 year: 2005 end-page: 2819 article-title: Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats publication-title: Circulation – volume: 46 start-page: 903 year: 2015 end-page: 975 article-title: 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: the Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT) publication-title: Eur Respir J – volume: 94 start-page: 1263 year: 2004 end-page: 1270 article-title: Serotonin-induced smooth muscle hyperplasia in various forms of human pulmonary hypertension publication-title: Circ Res – volume: 8 start-page: 2045894018759125 year: 2018 article-title: The serotonin hypothesis in pulmonary hypertension revisited: targets for novel therapies (2017 Grover Conference Series) publication-title: Pulm Circ – volume: 168 start-page: 487 year: 2003 end-page: 493 article-title: Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension publication-title: Am J Respir Crit Care Med – volume: 185 year: 2012 article-title: Proof of concept study to investigate the efficacy, hemodynamics and tolerability of terguride vs. placebo in subjects with pulmonary arterial hypertension: results of a double‐blind, randomized, prospective phase IIa study publication-title: Am J Respir Crit Care Med – volume: 313 start-page: 2142 year: 2015 end-page: 2151 article-title: Antidepressant use late in pregnancy and risk of persistent pulmonary hypertension of the newborn publication-title: JAMA – volume: 141 start-page: 348 year: 2012 end-page: 353 article-title: Selective serotonin reuptake inhibitors and pulmonary arterial hypertension: a case‐control study publication-title: Chest – volume: 111 start-page: 2812 year: 2005 end-page: 2819 article-title: Serotonin transporter inhibition prevents and reverses monocrotaline‐induced pulmonary hypertension in rats publication-title: Circulation – volume: 94 start-page: 1263 year: 2004 end-page: 1270 article-title: Serotonin‐induced smooth muscle hyperplasia in various forms of human pulmonary hypertension publication-title: Circ Res – volume: 98 start-page: 1323 year: 2006 end-page: 1330 article-title: Transgenic mice overexpressing the 5‐hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension publication-title: Circ Res – volume: 136 start-page: 694 year: 2009 end-page: 700 article-title: Selective serotonin reuptake inhibitors and the incidence and outcome of pulmonary hypertension publication-title: Chest – volume: 340 start-page: 480 year: 1999 end-page: 482 article-title: Primary pulmonary hypertension and anorectic drugs publication-title: N Engl J Med – volume: 117 start-page: 2928 year: 2008 end-page: 2937 article-title: Converging evidence in support of the serotonin hypothesis of dexfenfluramine‐induced pulmonary hypertension with novel transgenic mice publication-title: Circulation – volume: 46 start-page: 903 year: 2015 end-page: 975 article-title: 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: the Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT) publication-title: Eur Respir J – volume: 105 start-page: 1555 year: 2000 end-page: 1562 article-title: Attenuated hypoxic pulmonary hypertension in mice lacking the 5‐hydroxytryptamine transporter gene publication-title: J Clin Invest – volume: 66 start-page: 831 year: 2004 end-page: 836 article-title: Anxiety and depression in patients with pulmonary hypertension publication-title: Psychosom Med – volume: 19 start-page: 370 year: 2006 end-page: 374 article-title: Selective serotonin reuptake inhibitor use and outcomes in pulmonary arterial hypertension publication-title: Pulm Pharmacol Ther – volume: 144 start-page: 531 year: 2013 end-page: 541 article-title: Use of selective serotonin reuptake inhibitors and outcomes in pulmonary arterial hypertension publication-title: Chest – volume: 14 start-page: 303 year: 1987 end-page: 309 article-title: Acute hemodynamic response to the S2‐serotonergic receptor antagonist, ketanserin, in patients with primary pulmonary hypertension publication-title: Int J Cardiol – volume: 348 start-page: f6932 year: 2014 end-page: 01 article-title: Prenatal exposure to antidepressants and persistent pulmonary hypertension of the newborn: systematic review and meta‐analysis publication-title: BMJ – ident: e_1_2_2_12_1 doi: 10.1378/chest.08-2823 – ident: e_1_2_2_5_1 doi: 10.1161/01.RES.0000126847.27660.69 – ident: e_1_2_2_4_1 doi: 10.1172/JCI8678 – ident: e_1_2_2_16_1 doi: 10.1378/chest.11-0426 – ident: e_1_2_2_7_1 doi: 10.1161/CIRCULATIONAHA.104.524926 – ident: e_1_2_2_3_1 doi: 10.1161/01.RES.0000222546.45372.a0 – ident: e_1_2_2_6_1 doi: 10.1161/CIRCULATIONAHA.108.767558 – ident: e_1_2_2_11_1 doi: 10.1097/01.psy.0000145593.37594.39 – ident: e_1_2_2_18_1 doi: 10.1183/13993003.01032-2015 – ident: e_1_2_2_2_1 doi: 10.1177/2045894018759125 – ident: e_1_2_2_9_1 doi: 10.1016/0167-5273(87)90200-2 – volume: 185 year: 2012 ident: e_1_2_2_10_1 article-title: Proof of concept study to investigate the efficacy, hemodynamics and tolerability of terguride vs. placebo in subjects with pulmonary arterial hypertension: results of a double‐blind, randomized, prospective phase IIa study publication-title: Am J Respir Crit Care Med – ident: e_1_2_2_14_1 doi: 10.1016/j.pupt.2006.01.001 – ident: e_1_2_2_20_1 – ident: e_1_2_2_15_1 doi: 10.1378/chest.12-2081 – ident: e_1_2_2_8_1 doi: 10.1164/rccm.200210-1212OC – ident: e_1_2_2_17_1 doi: 10.1136/bmj.f6932 – ident: e_1_2_2_19_1 doi: 10.1001/jama.2015.5605 – ident: e_1_2_2_13_1 doi: 10.1056/NEJM199902113400614 |
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| SubjectTerms | Pulmonary hypertension Research Letter right heart catheterization treatment |
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| Title | Hemodynamic effects of fluoxetine in pulmonary arterial hypertension: an open label pilot study |
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